Výsledky vyhledávání - "Saimon Moraes Silva"

The impact of electrical stimulation protocols on neuronal cell survival and proliferation using cell-laden GelMA/graphene oxide hydrogels

Autor: Alexandre Xavier Mendes, Adriana Teixeira do Nascimento, Serena Duchi, Anita F. Quigley, Lilith M. Caballero Aguilar, Chaitali Dekiwadia, Robert M. I. Kapsa, Saimon Moraes Silva, Simon E. Moulton

Publikováno v: Journal of Materials Chemistry B. 11:581-593

The development of electroactive cell-laden hydrogels (bioscaffolds) has gained interest in neural tissue engineering research due to their inherent electrical properties that can induce the regulation of cell behaviour. Hydrogels combined with elect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7a1f42b9b89ee97a1d3143b7a8c7ee9
https://doi.org/10.1039/d2tb02387c

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Potential Pulse-Facilitated Active Adsorption of Lubricin Polymer Brushes Can Both Accelerate Self-Assembly and Control Grafting Density

Autor: Anita F. Quigley, George W. Greene, Robert M. I. Kapsa, Pauline Emilienne Desroches, Saimon Moraes Silva, Simon E. Moulton, Duangruedee Khwannimit

Publikováno v: Langmuir. 37:11188-11193

Self-assembled lubricin (LUB) monolayers are an effective antiadhesive coating for biomedical applications. Long deposition times and limited control over the monolayer grafting density remain impediments to commercialization and applications in adva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22382027ca30ba3446ec2972b0184169
https://doi.org/10.1021/acs.langmuir.1c02263

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Enhanced Electroactivity, Mechanical Properties, and Printability through the Addition of Graphene Oxide to Photo-Cross-linkable Gelatin Methacryloyl Hydrogel

Autor: Simon E. Moulton, Anita F. Quigley, Serena Duchi, Saimon Moraes Silva, Cathal D O'Connell, Robert M. I. Kapsa, Alexandre Xavier Mendes

Publikováno v: ACS Biomaterials Science & Engineering. 7:2279-2295

The human tissues most sensitive to electrical activity such as neural and muscle tissues are relatively soft, and yet traditional conductive materials used to interface with them are typically stiffer by many orders of magnitude. Overcoming this mis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db3a423f4bd70afd6a2e3bb644334283
https://doi.org/10.1021/acsbiomaterials.0c01734

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Antifouling Strategies for Electrochemical Biosensing: Mechanisms and Performance toward Point of Care Based Diagnostic Applications

Autor: Saimon Moraes Silva, Mingyu Han, Pauline Emilienne Desroches, Clayton S Manasa, Matthew J. Russo, Jessair Dennaoui, Simon E. Moulton, George W. Greene, Rosanne M. Guijt, Anita F. Quigley, Robert M. I. Kapsa

Publikováno v: ACS Sensors. 6:1482-1507

Although there exist numerous established laboratory-based technologies for sample diagnostics and analyte detection, many medical and forensic science applications require point of care based platforms for rapid on-the-spot sample analysis. Electroc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce2ca39f5441a4394003c6ca109b012d
https://doi.org/10.1021/acssensors.1c00390

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Self-Assembly of Lubricin (PRG-4) Brushes on Graphene Oxide Affords Stable 2D-Nanosheets in Concentrated Electrolytes and Complex Fluids

Autor: Weiwei Lei, Simon E. Moulton, Robert M. I. Kapsa, Mingyu Han, Mark Louis P. Vidallon, Rico F. Tabor, Anita F. Quigley, Saimon Moraes Silva, George W. Greene, Joseph D. Berry

Publikováno v: ACS Applied Nano Materials. 3:11527-11542

Graphene oxide (GO) and other 2D-nanosheet materials exhibit a range of useful physical, chemical, electrical, and optical properties that may usher in the next generation of biomedical, bioimaging...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5ef88139718a7bfd613b825b1ac65326
https://doi.org/10.1021/acsanm.0c02621

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A Simple Electrochemical Swab Assay for the Rapid Quantification of Clonazepam in Unprocessed Saliva Enabled by Lubricin Antifouling Coatings

Autor: George W. Greene, Saimon Moraes Silva, Robert M. I. Kapsa, Rosanne M. Guijt, Anita F. Quigley, Matthew J. Russo, Simon E. Moulton

Publikováno v: ChemElectroChem. 7:2851-2858

The electrochemical sensing of clonazepam in samples of unprocessed saliva is reported, using commercially available reduced graphene oxide (rGO) screen printed electrodes (SPEs). The rGO electrodes were modified with self-assembled lubricin (LUB) an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::023951d5fa015c0af72bab6c2b09d61d
https://doi.org/10.1002/celc.202000393

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Lubricin (PRG4) Antiadhesive Coatings Mitigate Electrochemical Impedance Instabilities in Polypyrrole Bionic Electrodes Exposed to Fouling Fluids

Autor: Pauline Emilienne Desroches, Robert M. I. Kapsa, Anita F. Quigley, George W. Greene, Simon E. Moulton, Shaun W. Gietman, Saimon Moraes Silva

Publikováno v: ACS applied bio materials. 3(11)

Surface fouling is a major problem faced by bionic implants (e.g., cochlear implants, pacemakers), where the adsorption of unwanted biomolecules has a detrimental effect on interfacial charge transfer processes, which severely impairs their capacity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d30be573c4ec457433e0f32d69561b70
https://pubmed.ncbi.nlm.nih.gov/35019542

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Cellular Interactions with Lubricin and Hyaluronic Acid-Lubricin Composite Coatings on Gold Electrodes in Passive and Electrically Stimulated Environments

Autor: Natalie Szin, Anita F. Quigley, Simon E. Moulton, Saimon Moraes Silva, George W. Greene, Robert M. I. Kapsa

Publikováno v: ACS biomaterials scienceengineering. 7(8)

In the field of bionics, the long-term effectiveness of implantable bionic interfaces depends upon maintaining a "clean" and unfouled electrical interface with biological tissues. Lubricin (LUB) is an innately biocompatible glycoprotein with impressi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::411c83c066e8f37d39c088afb4fc0103
https://pubmed.ncbi.nlm.nih.gov/34283570

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Adhesion and Self-Assembly of Lubricin (PRG4) Brush Layers on Different Substrate Surfaces

Autor: Saimon Moraes Silva, Robert M. I. Kapsa, Simon E. Moulton, Weiwei Lei, George W. Greene, Anita F. Quigley, Mingyu Han

Publikováno v: Langmuir. 35:15834-15848

Lubricin (LUB, aka PRG4), a mucin-like glycoprotein, is best known for the significant role it plays in the boundary lubrication, wear protection, and adhesion control systems in human joints. However, LUB exhibits a number of diverse and useful prop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b94623e40c7e46d57a176fca9c79199
https://doi.org/10.1021/acs.langmuir.9b01809

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Growth factor delivery: Defining the next generation platforms for tissue engineering

Autor: Simon E. Moulton, Lilith M Caballero Aguilar, Saimon Moraes Silva

Publikováno v: Journal of Controlled Release. 306:40-58

Growth factors play a crucial role in tissue engineering by directing the fate of cells and allowing the formation of tissues. Understanding the key requirements for growth factor delivery can point the way towards novel tissue engineering platforms.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49d43fb93d38be05f335f1a6aa6c297f
https://doi.org/10.1016/j.jconrel.2019.05.028

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