Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Saime Tan"'
Publikováno v:
Neurotoxicity Research
Pesticide exposure during in utero and early postnatal development can cause a wide range of neurological defects. However, relatively few insecticides have been recognized as developmental neurotoxicants, so far. Recently, discovery of the insectici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e76a2a1401aa2211241ea3941d65714
https://doi.org/10.1007/s12640-021-00364-8
https://doi.org/10.1007/s12640-021-00364-8
Autor:
Michael Stern, Grzegorz Podrygajlo, Gerd Bicker, Saime Tan, Million Adane Tegenge, Andrea Gierse, François Paquet-Durand
Publikováno v:
Cell and Tissue Research. 336:439-452
The well-characterized human teratocarcinoma line Ntera2 (NT2) can be differentiated into mature neurons. We have significantly shortened the time-consuming process for generating postmitotic neurons to approximately 4 weeks by introducing a differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58b42cb6e0bbfd561d6a4971c72299c6
https://doi.org/10.1007/s00441-009-0783-0
https://doi.org/10.1007/s00441-009-0783-0
Publikováno v:
ALTEX. :16-21
Mouse models for colon cancer that harbor a germ line mutation in the tumor suppressor gene Adenomatous polyposis coli (Apc) exhibit a primary genetic defect that predisposes to a high incidence of adenomatous polyps in the small intestine rather tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79eca259c50b7c365d394f266e0ae0e2
https://doi.org/10.14573/altex.2007.1.16
https://doi.org/10.14573/altex.2007.1.16
Publikováno v:
Developmental Brain Research. 142:161-167
Cells from the human teratocarcinoma line NTera-2 can be induced to terminally differentiate into postmitotic neurons when treated with retinoic acid. However, this differentiation process is rather time consuming as it takes between 42 and 54 days.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4caa0a2517344b73953a7e13e20e5769
https://doi.org/10.1016/s0165-3806(03)00065-8
https://doi.org/10.1016/s0165-3806(03)00065-8
Publikováno v:
Archives of toxicology. 88(1)
Developmental neurotoxicity (DNT) of environmental chemicals is a serious threat to human health. Current DNT testing guidelines propose investigations in rodents, which require large numbers of animals. With regard to the "3Rs" (reduction, replaceme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea43cd43ea1a9e71cf2a678279345d4e
https://pubmed.ncbi.nlm.nih.gov/23917397
https://pubmed.ncbi.nlm.nih.gov/23917397
Publikováno v:
ALTEX.
We describe a novel cell culture protocol for the generation of neurons from a human teratocarcinoma cell line. These neurons were used to investigate hypoxic-ischaemic cell damage and for developing neuroprotective strategies. Cultures of human mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6e3d7be43c013096cc2567d3ef6c13c4
https://pubmed.ncbi.nlm.nih.gov/19835047
https://pubmed.ncbi.nlm.nih.gov/19835047