Nestin as a regulator of Cdk5 in differentiating myoblasts

Autor: Tao He, Saima E. Ferraris, John E. Eriksson, Hanna-Mari Pallari, Cecilia Sahlgren, Elin Torvaldson, Julia Lindqvist

Publikováno v: Molecular Biology of the Cell
Pallari, H-M, Lindqvist, J, Torvaldson, E, Ferraris, S E, He, T, Sahlgren, C & Eriksson, J E 2011, ' Nestin as a regulator of Cdk5 in differentiating myoblasts ', Molecular Biology of the Cell, vol. 22, no. 9, pp. 1539-1549 . https://doi.org/10.1091/mbc.E10-07-0568
Molecular Biology of the Cell, 22(9), 1539-1549. American Society for Cell Biology

Our results show that the intermediate filament protein nestin regulates the early stages of myogenesis by a bidirectional interrelationship between nestin and Cdk5. Cdk5 regulates the organization and stability of its own scaffold nestin, which in t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::832c2730a077b46c3ce3b46d9ba958bd
https://doi.org/10.1091/mbc.e10-07-0568

Protein kinase Czeta regulates Cdk5/p25 signaling during myogenesis

Autor: Cecilia Sahlgren, Vitaly Kochin, Aurélie de Thonel, Shin-ichi Hisanaga, Hanna-Mari Pallari, Susumu Y. Imanishi, Saima E. Ferraris, Tomohisa Hosokawa, John E. Eriksson

Publikováno v: Molecular Biology of the Cell
Molecular Biology of the Cell, American Society for Cell Biology, 2010, 21 (8), pp.1423-1434. ⟨10.1091/mbc.e09-10-0847⟩
Molecular Biology of the Cell, 21(8), 1423-1434. American Society for Cell Biology

Atypical protein kinase Cζ (PKCζ) is emerging as a mediator of differentiation. Here, we describe a critical role for PKCζ during myogenic differentiation. Our results identify PKCζ as a controller of myogenic differentiation by its regulation of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4e5d691c65d55f6eb34ddf2bad22805
https://pubmed.ncbi.nlm.nih.gov/20200223