Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Saima Ajaz"'
Autor:
Saima Ajaz, Mark Chamley, James Lok, Riham Soliman, Reece Khan, Karan Ahir, Monique Curtis, María Fernanda Guerra-Veloz, Kosh Agarwal
Publikováno v:
Therapeutic Advances in Chronic Disease, Vol 15 (2024)
Background: Metabolic associated fatty liver disease (MAFLD) stands as the leading cause of chronic liver disease globally. Notably, individuals with metabolic risk factors, such as diabetes and obesity, exhibit a staggering prevalence of MAFLD, with
Externí odkaz:
https://doaj.org/article/d6c2f9248dfc42f487abcf929983a9b6
Autor:
Anna Czajka, Saima Ajaz, Luigi Gnudi, Chandani Kiran Parsade, Peter Jones, Fiona Reid, Afshan N. Malik
Publikováno v:
EBioMedicine, Vol 2, Iss 6, Pp 499-512 (2015)
The purpose of this study was to determine if mitochondrial dysfunction plays a role in diabetic nephropathy (DN), a kidney disease which affects >100 million people worldwide and is a leading cause of renal failure despite therapy. A cross-sectional
Externí odkaz:
https://doaj.org/article/514890d9859e4b8cbf72f2b92f8f9a22
Autor:
Khin Han, Ngozi Adibe, Saima Ajaz, Almuthana Mohamed, Maria Guerra-Veloz, James Lok, Ivana Carey, Kosh Agarwal
Publikováno v:
Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49a6b4870bf26971de4d113516532565
https://doi.org/10.1136/gutjnl-2022-basl.105
https://doi.org/10.1136/gutjnl-2022-basl.105
Autor:
Mark J. W. McPhail, Kosh Agarwal, Saima Ajaz, Salma F Mujib, Keshav K. Singh, Salvatore Napoli, Francesca M. Trovato
Publikováno v:
American Journal of Physiology-Cell Physiology
The COVID-19 pandemic has been the primary global health issue since its outbreak in December 2019. Patients with metabolic syndrome suffer from severe complications and a higher mortality rate due to severe acute respiratory syndrome coronavirus 2 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf847c064b321e3b77d27c50aa9660ed
https://doi.org/10.1152/ajpcell.00426.2020
https://doi.org/10.1152/ajpcell.00426.2020
Publikováno v:
Journal of Hepatology. 77:S171
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::509b0729d6ade811fcf7a23a900c004f
https://doi.org/10.1016/s0168-8278(22)00721-8
https://doi.org/10.1016/s0168-8278(22)00721-8
Autor:
Salma F Mujib, Luigi Gnudi, Kosh Agarwal, Mark J. W. McPhail, Salvatore Napoli, Francesca M. Trovato, Saima Ajaz, Ivana Carey
Publikováno v:
Mitochondrion. 57
Dysfunctional metabolism lies at the centre of the pathogenesis for Non-Alcoholic Fatty Liver Disease (NAFLD) and involves mitochondrial dysfunction, lipid dysmetabolism and oxidative stress. This study, for the first time, explores real-time energy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e5b83a2af9a8e5fa1593a5d73c9ba1
https://pubmed.ncbi.nlm.nih.gov/33387664
https://pubmed.ncbi.nlm.nih.gov/33387664
Autor:
Sobha Sivaprasad, Saima Ajaz, Anna Czajka, Afshan N. Malik, Chandani Kiran Parsade, Roxanne Crosby-Nwaobi, Luigi Gnudi
Publikováno v:
Diabetes Research and Clinical Practice. 110:257-265
Aims We previously showed that circulating mitochondrial DNA (MtDNA) levels are altered in diabetic nephropathy. The aim of the current study was to determine if circulating MtDNA levels are altered in patients with diabetic retinopathy. Methods Pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9386fc69c3329c9409e6d466dc9211a
https://doi.org/10.1016/j.diabres.2015.10.006
https://doi.org/10.1016/j.diabres.2015.10.006
Autor:
Luigi Gnudi, Saima Ajaz, Afshan N. Malik, Chandani Kiran Parsade, Peter M. Jones, Anna Czajka, Fiona Reid
Publikováno v:
EBioMedicine
Czajka, A, Ajaz, S, Gnudi, L, Parsade, C K, Jones, P, Reid, F & Malik, A N 2015, ' Altered Mitochondrial Function, Mitochondrial DNA and Reduced Metabolic Flexibility in Patients With Diabetic Nephropathy ', EBioMedicine, vol. 2, no. 6, pp. 499-512 . https://doi.org/10.1016/j.ebiom.2015.04.002
EBioMedicine, Vol 2, Iss 6, Pp 499-512 (2015)
Czajka, A, Ajaz, S, Gnudi, L, Parsade, C K, Jones, P, Reid, F & Malik, A N 2015, ' Altered Mitochondrial Function, Mitochondrial DNA and Reduced Metabolic Flexibility in Patients With Diabetic Nephropathy ', EBioMedicine, vol. 2, no. 6, pp. 499-512 . https://doi.org/10.1016/j.ebiom.2015.04.002
EBioMedicine, Vol 2, Iss 6, Pp 499-512 (2015)
The purpose of this study was to determine if mitochondrial dysfunction plays a role in diabetic nephropathy (DN), a kidney disease which affects > 100 million people worldwide and is a leading cause of renal failure despite therapy. A cross-sectiona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6216a4bd8e2db28fd2f8ff0913d7adb
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1264
We describe a protocol to accurately measure the amount of human mitochondrial DNA (MtDNA) in peripheral blood samples which can be modified to quantify MtDNA from other body fluids, human cells, and tissues. This protocol is based on the use of real
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c37aa6ba10abf546eeb2bcf64f5ea380
https://pubmed.ncbi.nlm.nih.gov/25631009
https://pubmed.ncbi.nlm.nih.gov/25631009
Publikováno v:
Methods in Molecular Biology ISBN: 9781493922567
We describe a protocol to accurately measure the amount of human mitochondrial DNA (MtDNA) in peripheral blood samples which can be modified to quantify MtDNA from other body fluids, human cells, and tissues. This protocol is based on the use of real
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5917fed7bd22cee622c22ed33682a502
https://doi.org/10.1007/978-1-4939-2257-4_12
https://doi.org/10.1007/978-1-4939-2257-4_12