Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Sailendra Nath Sarma"'
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2687 (2019)
Background: The neurological effects of short-term dioxin exposure during the fetal period is an important health risk in humans. Here, we investigated the effects of dioxin on neural differentiation using human embryonic stem cells (hESCs) to evalua
Externí odkaz:
https://doaj.org/article/a1c6ad792c514a4592c69f6b912f9cf1
Autor:
Birgit M Braune, Mark L. Mallory, Bruce D. Pauli, Ryan P. Franckowiak, Guy Savard, Doug Crump, Sailendra Nath Sarma, Yasmeen Zahaby, Michel Gendron, Jason M. O'Brien, Philippe J. Thomas, Jennifer F. Provencher, Pu Xia
Publikováno v:
Environmental Science & Technology. 55:7521-7530
Increasing pollution in the Arctic poses challenges in terms of geographical and ecological monitoring. The Baffin Bay-Davis Strait (BBDS) region in the Canadian Arctic Archipelago is of particular concern due to the potential for increased shipping
Autor:
Charvi Syal, Jayasankar Kosaraju, Jacob Thomas, Matthew Seegobin, Ling He, F. Jeffrey Dilworth, Anne Aumont, Jing Wang, Laura K. Hamilton, Robert Zimmermann, Karl J.L. Fernandes, Sailendra Nath Sarma, Martin Parent, Fredric E. Wondisford, Alphonse Chu
Publikováno v:
Theranostics
Rationale: Monoacylglycerol lipase (Mgll), a hydrolase that breaks down the endocannabinoid 2-arachidonoyl glycerol (2-AG) to produce arachidonic acid (ARA), is a potential target for neurodegenerative diseases, such as Alzheimer's disease (AD). Incr
Autor:
Cynthia Cheney, Martin Pothier, Philippe J. Thomas, Sailendra Nath Sarma, Alexandre J. Poulain, Jules M. Blais
Publikováno v:
Aquatic Toxicology. 250:106248
The contamination of lakes by industrial emissions is an issue of international concern. Traditional paleolimnology examines sedimentary micro-fossils to infer the biological response to natural and anthropogenic stressors over time. Here, we calcula
Autor:
Michel Gendron, Ryan P. Franckowiak, Doug Crump, Jason M. O'Brien, Philippe J. Thomas, Bruce D. Pauli, Yasmeen Zahaby, Sailendra Nath Sarma, Jennifer F. Provencher, Shama Naz, Mark L. Mallory
Publikováno v:
Environmental research. 204
While exposure of birds to oil-related contaminants has been documented, the related adverse effects this exposure has on Arctic marine birds remain unexplored. Metabolomics can play an important role to explore biologically relevant metabolite bioma
Autor:
Fredric E. Wondisford, Matthew Seegobin, Jing Wang, Ling He, Charvi Syal, Ayden Gouveia, Julius Ilin, Jayasankar Kosaraju, Kevin Jiaqi Lu, Diane C. Lagace, Sailendra Nath Sarma, Rashmi Kothary, Yves De Repentigny
Publikováno v:
Experimental neurology. 334
Individuals with demyelinating diseases often experience difficulties during social interactions that are not well studied in preclinical models. Here, we describe a novel juvenile focal corpus callosum demyelination murine model exhibiting a social
Autor:
Ammar Saleem, Jin-Yong Lee, Masahiko Satoh, Hing Man Chan, Gi Wook Hwang, Sailendra Nath Sarma, Maki Tokumoto
Publikováno v:
The Journal of Toxicological Sciences. 43:89-100
Cadmium (Cd) is a common environmental pollutant with known toxic effects on the kidney. Urinary metabolomics is a promising approach to study mechanism by which Cd-induced nephrotoxicity. The aim of this study was to elucidate the mechanism of Cd to
Autor:
Jennifer F. Provencher, Mark L. Mallory, Yasmeen Zahaby, Sailendra Nath Sarma, Michel Gendron, Guy Savard, Doug Crump, Birgit M Braune, Bruce D. Pauli, Philippe J. Thomas, Ryan P. Franckowiak, Jason M. O'Brien
Publikováno v:
Science of The Total Environment. 764:144682
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2687 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 11
International Journal of Molecular Sciences
Volume 20
Issue 11
Background: The neurological effects of short-term dioxin exposure during the fetal period is an important health risk in humans. Here, we investigated the effects of dioxin on neural differentiation using human embryonic stem cells (hESCs) to evalua
Publikováno v:
Environmental research. 178
Polyaromatic compounds (PACs) are by-products of combustion and are the major pollutants from the oil and gas industry. However, the mechanism of PACs induced toxicity still remains elusive. The aim of this study was to elucidate the effects of a typ