Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Sailay Siddiqi"'
Autor:
Tim Somers, Neeltje A. E. Allard, Sailay Siddiqi, Margit C. M. Janssen, Maria T. E. Hopman, Wim J. Morshuis, Frans G. M. Russel, Silvie Timmers, Tom J. J. Schirris
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Drug-induced mitochondrial dysfunction is a common adverse effect, particularly in case of statins—the most prescribed drugs worldwide. These drugs have been shown to inhibit complex III (CIII) of the mitochondrial oxidative phosphorylatio
Externí odkaz:
https://doaj.org/article/07377571bfc6436db3445afffa3a5dad
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 10, Iss 10, p 417 (2023)
Statins inhibit HMG-CoA reductase, the rate-limiting enzyme in cholesterol synthesis, and are the cornerstone of lipid-lowering treatment. They significantly reduce cardiovascular morbidity and mortality. However, musculoskeletal symptoms are observe
Externí odkaz:
https://doaj.org/article/0369d11886e34b0fbea49a9a76ae6a9e
Autor:
Andrea Raso, Ellen Dirkx, Vasco Sampaio-Pinto, Hamid el Azzouzi, Ryan J. Cubero, Daniel W. Sorensen, Lara Ottaviani, Servé Olieslagers, Manon M. Huibers, Roel de Weger, Sailay Siddiqi, Silvia Moimas, Consuelo Torrini, Lorena Zentillin, Luca Braga, Diana S. Nascimento, Paula A. da Costa Martins, Jop H. van Berlo, Serena Zacchigna, Mauro Giacca, Leon J. De Windt
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Myocardial regeneration and proliferation of heart muscle cells is limited to a short period after birth early postnatal life, after which heart muscle cells can only grow in size and not in number. Here, the authors identified that the expression le
Externí odkaz:
https://doaj.org/article/940312e06d484466827c2f7aaaa0a4ae
Autor:
Andrea Raso, Ellen Dirkx, Vasco Sampaio-Pinto, Hamid el Azzouzi, Ryan J. Cubero, Daniel W. Sorensen, Lara Ottaviani, Servé Olieslagers, Manon M. Huibers, Roel de Weger, Sailay Siddiqi, Silvia Moimas, Consuelo Torrini, Lorena Zentillin, Luca Braga, Diana S. Nascimento, Paula A. da Costa Martins, Jop H. van Berlo, Serena Zacchigna, Mauro Giacca, Leon J. De Windt
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/82ddc211aa884ddea4f743c7628acbd6
Autor:
Manon Meerman, Tom C. L. Bracco Gartner, Jan Willem Buikema, Sean M. Wu, Sailay Siddiqi, Carlijn V. C. Bouten, K. Jane Grande-Allen, Willem J. L. Suyker, Jesper Hjortnaes
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Radiation-induced cardiovascular disease is a well-known complication of radiation exposure. Over the last few years, planning for deep space missions has increased interest in the effects of space radiation on the cardiovascular system, as an increa
Externí odkaz:
https://doaj.org/article/bd92e417992740e295942ac2d7d073f0
Autor:
Nan Liu, Bingyan J Wang, Kathleen M Broughton, Roberto Alvarez, Sailay Siddiqi, Rebeca Loaiza, Nicky Nguyen, Pearl Quijada, Natalie Gude, Mark A Sussman
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173963 (2017)
PIM1, a pro-survival gene encoding a serine/ threonine kinase, influences cell proliferation and survival. Modification of cardiac progenitor cells (CPCs) or cardiomyocytes with PIM1 using a lentivirus-based delivery method showed long-term improved
Externí odkaz:
https://doaj.org/article/375ca4ddb5724a1b88f7feee99257ba0
Autor:
Janine C Deddens, Dries A Feyen, Peter-Paul Zwetsloot, Maike A Brans, Sailay Siddiqi, Linda W van Laake, Pieter A Doevendans, Joost P Sluijter
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173657 (2017)
BACKGROUND:Translational failure for cardiovascular disease is a substantial problem involving both high research costs and an ongoing lack of novel treatment modalities. Despite the progress already made, cell therapy for chronic heart failure in th
Externí odkaz:
https://doaj.org/article/dee237f3901c4a51bb48a9f66a2cd7b4
Autor:
Vasco Sampaio-Pinto, Lara Ottaviani, Luca Braga, Roel A. de Weger, Leon J. De Windt, Lorena Zentillin, Daniel W. Sorensen, Jop H. van Berlo, Andrea Raso, Serena Zacchigna, Silvia Moimas, Paula A. da Costa Martins, Diana S. Nascimento, Manon M. H. Huibers, Hamid el Azzouzi, Ellen Dirkx, Sailay Siddiqi, Ryan John Cubero, Servé Olieslagers, Consuelo Torrini, Mauro Giacca
Publikováno v:
Nature Communications, 12(1):4808. Nature Publishing Group
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Myocardial regeneration is restricted to early postnatal life, when mammalian cardiomyocytes still retain the ability to proliferate. The molecular cues that induce cell cycle arrest of neonatal cardiomyocytes towards terminally differentiated adult
Autor:
Monica Chavarria, Roberto Alvarez, Pearl Quijada, Kathleen M. Broughton, Megan M. Monsanto, Thi Ho, Mark A. Sussman, Maya Shaitrit, David E. Ebeid, Natalie Navarrete, Bingyan J. Wang, Maryam Moshref, Daniele Avitabile, Barbara A. Bailey, Fareheh Firouzi, Natalie Gude, Sailay Siddiqi
Publikováno v:
Journal of Molecular and Cellular Cardiology. 127:154-164
Rationale Understanding and manipulating the cardiomyocyte cell cycle has been the focus of decades of research, however the ultimate goal of activating mitotic activity in adult mammalian cardiomyocytes remains elusive and controversial. The relentl
Autor:
Egbert Oosterwijk, Ad F.T.M. Verhagen, Rayna de Wit, Dorien M. Tiemessen, Sailay Siddiqi, Rebecca Snabel, Gert Jan C. Veenstra
Publikováno v:
Journal of Cellular and Molecular Medicine, 25, 10869-10878
Journal of Cellular and Molecular Medicine, 25, 23, pp. 10869-10878
Journal of Cellular and Molecular Medicine
Journal of Cellular and Molecular Medicine, 25, 23, pp. 10869-10878
Journal of Cellular and Molecular Medicine
Contains fulltext : 244255.pdf (Publisher’s version ) (Open Access) Tissue engineering (TE) of long tracheal segments is conceptually appealing for patients with inoperable tracheal pathology. In tracheal TE, stem cells isolated from bone marrow or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e06e9881a9b002e3cafd5ca3cc1a9e4
https://doi.org/10.1111/jcmm.16916
https://doi.org/10.1111/jcmm.16916