Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Saila Laakso"'
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2024)
ObjectiveChildren with inflammatory bowel disease (IBD) often suffer from poor bone growth and impaired bone health. Humanin is a cytoprotective factor expressed in bone and other tissues and we hypothesized that humanin levels are suppressed in cond
Externí odkaz:
https://doaj.org/article/3ff2b93082ee42e093977733db53d91f
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
ContextHypokalemia is a common finding in patients with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) but its exact cause often remains unknown.ObjectiveTo explore the prevalence and etiology of hypokalemia and the role of a
Externí odkaz:
https://doaj.org/article/b8dc7d9f6f9a42179ff91dc95e911626
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
ObjectiveIn autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) defects in the autoimmune regulator gene lead to impaired immunotolerance. We explored the effects of immunodeficiency and endocrinopathies on gynecologic health in p
Externí odkaz:
https://doaj.org/article/7bb83e91f9aa43cebd1abe83396eda42
Autor:
Iivo Hetemäki, Ching Jian, Saila Laakso, Outi Mäkitie, Anne-Maria Pajari, Willem M. de Vos, T. Petteri Arstila, Anne Salonen
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Backgrounds and AimsAPECED is a rare autoimmune disease caused by mutations in the Autoimmune Regulator gene. A significant proportion of patients also have gastrointestinal symptoms, including malabsorption, chronic diarrhea, and obstipation. The pa
Externí odkaz:
https://doaj.org/article/3597030e3b064c45858cefac12a689b6
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Objective: Immunological abnormalities, the resulting endocrinopathies and their treatments may impact bone health in patients with autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy (APECED, APS1). The aim of the present study was to
Externí odkaz:
https://doaj.org/article/55ea337c4821410cab547e40b76a2f0e
Autor:
Øyvind Bruserud, Daniela-Elena Costea, Saila Laakso, Ben-Zion Garty, Eirik Mathisen, Antti Mäkitie, Outi Mäkitie, Eystein S. Husebye
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) or Autoimmune polyendocrine syndrome type-1 (APS-1) (APECED, OMIM 240300) is a rare, childhood onset, monogenic disease caused by mutations in the Autoimmune Regulator (AIRE) gen
Externí odkaz:
https://doaj.org/article/e9d1c9da8a214594b4bd29db8ba9a22f
Autor:
Saila Laakso, Tong Xiaoyu, Stéphane Blouin, Petra Keplinger, Ville-Valtteri Välimäki, Heikki Kröger, Outi Mäkitie, Markus A. Hartmann
Publikováno v:
Calcified Tissue International. 112:675-682
Autoimmune polyendocrine syndrome type-1 (APS1) is characterized by autoimmune manifestations affecting different organs from early childhood on. Immunological abnormalities, the resulting endocrinopathies, and their treatments may compromise bone he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a79589c51879f1abb526df70227e638a
https://doi.org/10.1007/s00223-023-01077-0
https://doi.org/10.1007/s00223-023-01077-0
Autor:
Emilia Träskilä, Elina Holopainen, Mikko I Mäyränpää, Jorma Toppari, Outi Mäkitie, Saila Laakso
Publikováno v:
European Journal of Endocrinology. 188:K17-K23
The aim of this study was to describe the course of puberty and hypogonadism in males with autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy (APECED) in a Finnish APECED cohort followed up between 1970 and 2020. Anthropometry, testic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08f874b9a22e46b69dd10df971b2465e
https://doi.org/10.1093/ejendo/lvad034
https://doi.org/10.1093/ejendo/lvad034
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism.
Objective Incidence and causes of primary adrenal insufficiency (PAI) have not been comprehensively studied in children. Our objective was to describe the epidemiology and to assess causes of PAI in Finnish children. Design A population-based descrip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::867f07775b8133e93e94104c7acb371c
https://doi.org/10.1210/clinem/dgad283
https://doi.org/10.1210/clinem/dgad283
Autor:
Monica M. Schmitt, Michail S. Lionakis, Viivi Saari, Maria Kareva, Corrado Betterle, Chiara Sabbadin, Elinor Chelsom Vogt, Saila Laakso, Outi Mäkitie, Karen K. Winer, Eystein S. Husebye, Elizaveta Orlova, Elina Holopainen
Publikováno v:
Journal of Clinical Endocrinology and Metabolism (JCEM)
e528–e537
The Journal of Clinical Endocrinology and Metabolism
e528–e537
The Journal of Clinical Endocrinology and Metabolism
Context Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED; also known as autoimmune polyendocrine syndrome type 1) has a severe, unpredictable course. Autoimmunity and disease components may affect fertility and predispose to mat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddc2d09d80f1eda317cbbd5f740911f2
https://doi.org/10.1210/clinem/dgab705
https://doi.org/10.1210/clinem/dgab705