Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Saila Holopainen"'
Autor:
Sirkku Kouki, Sanna J. Viitanen, Ninna Koho, Henna P. Laurila, Liisa Lilja‐Maula, Saila Holopainen, Mikko Neuvonen, Mikko Niemi, Aline Fastrès, Cécile Clercx, Minna M. Rajamäki
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 37, Iss 1, Pp 268-276 (2023)
Abstract Background Salivary bile acids are used to diagnose extraesophageal reflux (EER) and to evaluate the risk of reflux aspiration that is associated with respiratory diseases in dogs. Objectives To study total bile acid (TBA) concentrations in
Externí odkaz:
https://doaj.org/article/7e536a3c944f4d889f1c7b0269d8196b
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 36, Iss 4, Pp 1202-1210 (2022)
Abstract Background Prolonged tissue hypoxia caused by chronic pulmonary disease is commonly regarded as an important mechanism in the development of secondary polycythemia, but little clinical data are available to support this hypothesis. Objective
Externí odkaz:
https://doaj.org/article/79bfcffc70db4444a9a1a49fbd2a9c1b
Autor:
Merita Määttä, Henna P. Laurila, Saila Holopainen, Kaisa Aaltonen, Liisa Lilja‐Maula, Sanna Viitanen, Minna M. Rajamäki
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 35, Iss 1, Pp 462-471 (2021)
Abstract Background Canine idiopathic pulmonary fibrosis (CIPF) is a chronic, interstitial lung disease that mainly affects West Highland white terriers (WHWTs) and is characterized by excessive deposition of extracellular matrix (ECM) in the lung. M
Externí odkaz:
https://doaj.org/article/6034fe34483a42888f9098dd28c3c34a
Autor:
Lea Mikkola, Saila Holopainen, Tiina Pessa-Morikawa, Anu K. Lappalainen, Marjo K. Hytönen, Hannes Lohi, Antti Iivanainen
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-13 (2019)
Abstract Background Hip dysplasia and osteoarthritis continue to be prevalent problems in veterinary and human medicine. Canine hip dysplasia is particularly problematic as it massively affects several large-sized breeds and can cause a severe impair
Externí odkaz:
https://doaj.org/article/6e84ed6cd5a24890ad3bf33d766d7782
Autor:
Maria Kaukonen, Ileana B Quintero, Abdul Kadir Mukarram, Marjo K Hytönen, Saila Holopainen, Kaisa Wickström, Kaisa Kyöstilä, Meharji Arumilli, Sari Jalomäki, Carsten O Daub, Juha Kere, Hannes Lohi, DoGA Consortium
Publikováno v:
PLoS Genetics, Vol 16, Iss 3, p e1008659 (2020)
Retinitis pigmentosa (RP) is the leading cause of blindness with nearly two million people affected worldwide. Many genes have been implicated in RP, yet in 30-80% of the RP patients the genetic cause remains unknown. A similar phenotype, progressive
Externí odkaz:
https://doaj.org/article/39d51ff8395f4e6585da637aea5f289e
Autor:
Lea I Mikkola, Saila Holopainen, Anu K Lappalainen, Tiina Pessa-Morikawa, Thomas J P Augustine, Meharji Arumilli, Marjo K Hytönen, Osmo Hakosalo, Hannes Lohi, Antti Iivanainen
Publikováno v:
PLoS Genetics, Vol 15, Iss 7, p e1008197 (2019)
Canine hip dysplasia is a common, non-congenital, complex and hereditary disorder. It can inflict severe pain via secondary osteoarthritis and lead to euthanasia. An analogous disorder exists in humans. The genetic background of hip dysplasia in both
Externí odkaz:
https://doaj.org/article/3bbb4250dd4f494289b52428242f31ab
Autor:
Saila Holopainen, Marjo K Hytönen, Pernilla Syrjä, Meharji Arumilli, Anna-Kaisa Järvinen, Minna Rajamäki, Hannes Lohi
Publikováno v:
PLoS Genetics, Vol 13, Iss 2, p e1006625 (2017)
Acute respiratory distress syndrome (ARDS) is the leading cause of death in critical care medicine. The syndrome is typified by an exaggerated inflammatory response within the lungs. ARDS has been reported in many species, including dogs. We have pre
Externí odkaz:
https://doaj.org/article/d87faa9db1c94a0fab15fc2d5d12b233
Autor:
O. L. Merita Määttä, HP Laurila, Saila Holopainen, Minna M. Rajamäki, Liisa Lilja-Maula, Sanna Johanna Viitanen, Kaisa Aaltonen
Publikováno v:
Journal of Veterinary Internal Medicine
Background Canine idiopathic pulmonary fibrosis (CIPF) is a chronic, interstitial lung disease that mainly affects West Highland white terriers (WHWTs) and is characterized by excessive deposition of extracellular matrix (ECM) in the lung. Matrix met
Autor:
Saila Holopainen, Tiina Pessa-Morikawa, Lea Mikkola, Hannes Lohi, Marjo K. Hytönen, Antti Iivanainen, Anu K. Lappalainen
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-13 (2019)
BMC Genomics
BMC Genomics
Background Hip dysplasia and osteoarthritis continue to be prevalent problems in veterinary and human medicine. Canine hip dysplasia is particularly problematic as it massively affects several large-sized breeds and can cause a severe impairment of t
Publikováno v:
Journal of veterinary internal medicine. 36(4)
Prolonged tissue hypoxia caused by chronic pulmonary disease is commonly regarded as an important mechanism in the development of secondary polycythemia, but little clinical data are available to support this hypothesis.To study the prevalence and se