A Combinatorial Cell and Drug Delivery Strategy for Huntington’s Disease Using Pharmacologically Active Microcarriers and RNAi Neuronally-Committed Mesenchymal Stromal Cells

Autor: Emilie M. André, Gaëtan J. Delcroix, Saikrishna Kandalam, Laurence Sindji, Claudia N. Montero-Menei

Publikováno v: Pharmaceutics, Vol 11, Iss 10, p 526 (2019)

For Huntington’s disease (HD) cell-based therapy, the transplanted cells are required to be committed to a neuronal cell lineage, survive and maintain this phenotype to ensure their safe transplantation in the brain. We first investigated the role

Externí odkaz: https://doaj.org/article/5815a59a632f42b7ae39f2f48dd92675

Contributors

Autor: Muzaffar Abbas, Nasir Abbas, Alaa A.A. Aljabali, Walhan Alshaer, Nizar A. Al-Shar’i, Krishnan Anand, Roy Anitha, Alice Ao, Vimal Arora, Vijaya Anand Arumugam, Balamuralikrishnan Balasubramanian, Ratnali Bania, Seema Bansal, Anindita Behera, Helen Benson, Sanjay Kumar Bharti, Amit Bhatia, Shvetank Bhatt, Pobitra Borah, Victoria Garcia Cardenas, Natalia Neto Pereira Cerize, Yinghan Chan, Balakumar Chandrasekaran, Nitin Bharat Charbe, Shashank Chaturvedi, Pooja A. Chawla, Viney Chawla, Dinesh Kumar Chellappan, Kiran Kumar Chereddy, Shruti Chopra, Rachelle L. Cutler, Lina A. Dahabiyeh, Rajiv Dahiya, Sunita Dahiya, Joydeep Das, Terezinha de Jesus Andreoli Pinto, Pran Kishore Deb, Satyendra Deka, Anju Dhiman, Kamal Dua, Harish Dureja, Sreenivas Enaganti, Devaraj Ezhilarasan, Valker Araujo Feitosa, Ireen Femeela, Gasper Fernandes, Lakshmi Pallavi Ganipineni, Ashish Garg, Sweta Garg, Rupesh K. Gautam, Ritu Gilhotra, Charles Gnanaraj, Manoj Goyal, Monica Gulati, Gaurav Gupta, Mehra Hagi, Khalid Hussain, Salman Hussain, Nadeem Irfan Bukhari, Gaurav Kumar Jain, Rupa Joshi, Saikrishna Kandalam, Ummarah Kanwal, Deepak N. Kapoor, Ritu Karwasra, Harpinder Kaur, Sanjay Kulkarni, Deepak Kumar, Dileep Kumar, Nitesh Kumar, Subodh Kumar, Varun Kumar, H. Lalhlenmawia, Wing-Hin Lee, Ching-Yee Loo, Debarshi Kar Mahapatra, Saniya Mahendiratta, Deepti Malik, Subha Manoharan, Pawan Kumar Maurya, Priyanka Maurya, Bikash Medhi, Akansha Mehra, Meenu Mehta, Brahmeshwar Mishra, Neeraj Mishra, Nidhi Mishra, Dhrubojyoti Mukherjee, Srinivas Mutalik, Anroop B. Nair, Mukesh Nandave, Sin Wi Ng, Xin Yi Ng, Ajinkya NIkam (Nitin), null Nimisha, Raquibun Nisha, Mohammad A. Obeid, Santwana Padhi, Bharath Singh Padya, Ajay Kumar Pal, Abhijeet Pandey, Kalpana Pandey, Chandrakantsing V. Pardeshi, Kamla Pathak, Tania Patwal, Atmaram Pawar, Anil Philip, Lisa G. Pont, Ajay Prakash, Parteek Prasher, Gopal Kumar Rai, Alan Raj, Sushma Rawat, Abida Raza, Faizan Naeem Razali, Sangita Saini, Betty Annie Samuel, Shubhini A. Saraf, Mohammad Arshad Shaikh, C. Sarath Chandran, Phulen Sarma, Saurabh Satija, T.K. Shahin Muhammed, Mousmee Sharma, Nitin Sharma, Ganesh B. Shevalkar, Priya Shrivastava, Ajay Shukla, Apoorva Singh, Juhi Singh, Lubhan Singh, Neelu Singh, Priya Singh, Sachin Kumar Singh, Samipta Singh, Santosh Kumar Singh, Vinayak Singh, Yogendra Singh, Chloe C.H. Smit, Sanjay J. Surana, Murtaza M. Tambuwala, Rakesh Kumar Tekade, Lakshmi Thangavelu, Komal Thapa, Rajiv K. Tonk, Mansi Upadhyay, Katharigatta N. Venugopala, Dhriti Verma, Nitin Verma, Kylie A. Williams, Nisha R. Yadav, Rati Yadav, Farrukh Zeeshan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1c9cdda9df725619d69ddee3e131693f
https://doi.org/10.1016/b978-0-323-85503-7.09990-9

Pharmacologically active microcarriers delivering BDNF within a hydrogel: Novel strategy for human bone marrow-derived stem cells neural/neuronal differentiation guidance and therapeutic secretome enhancement

Autor: Paul C. Schiller, Marie Claire Venier-Julienne, Jérôme Guicheux, Xavier Garric, Claudia N. Montero-Menei, Anne des Rieux, Saikrishna Kandalam, Fabien Violet, Gaëtan J.-R. Delcroix, Emilie M. André, Laurence Sindji

Publikováno v: Acta Biomaterialia
Acta Biomaterialia, Elsevier, 2017, 49, pp.167-180. ⟨10.1016/j.actbio.2016.11.030⟩
Acta Biomaterialia, 2017, 49, pp.167-180. ⟨10.1016/j.actbio.2016.11.030⟩

Stem cells combined with biodegradable injectable scaffolds releasing growth factors hold great promises in regenerative medicine, particularly in the treatment of neurological disorders. We here integrated human marrow-isolated adult multilineage-in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f3a74d0729861afccea8eae22d94824
https://www.hal.inserm.fr/inserm-01845036

The growth factor multimodality on treating human dental mesenchymal stem cells: a systematic review.

Autor: He, Huiying, Yang, Yun-Hsuan, Yang, Xuesong, Huang, Yue

Publikováno v: BMC Oral Health; 3/1/2024, Vol. 24 Issue 1, p1-11, 11p

Advanced Drug Delivery Systems in the Management of Cancer

Autor: Kamal Dua, Meenu Mehta, Terezinha de Jesus Andreoli Pinto, Lisa G. Pont, Kylie A. Williams, Michael Rathbone

Advanced Drug Delivery Systems in the Management of Cancer discusses recent developments in nanomedicine and nano-based drug delivery systems used in the treatment of cancers affecting the blood, lungs, brain, and kidneys. The research presented in t