Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Saija Savolainen"'
Autor:
Tero Aittokallio, Matti Poutanen, Sari Mäkelä, Esa Alhoniemi, Mari I. Suominen, Saija Savolainen, Katja Mäkelä, Niina M. Saarinen, Jukka Corander, Teemu D. Laajala
PDF file, 933K, Full model formulation and details of its estimation, inference and validation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b35e2d9b6cf0ec65f684fc0ba7dafed3
https://doi.org/10.1158/1078-0432.22445606
https://doi.org/10.1158/1078-0432.22445606
Autor:
Tero Aittokallio, Matti Poutanen, Sari Mäkelä, Esa Alhoniemi, Mari I. Suominen, Saija Savolainen, Katja Mäkelä, Niina M. Saarinen, Jukka Corander, Teemu D. Laajala
PDF file, 1943K, Data on real and simulated tumor growth experiments and power and precision analyses.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cda36d29d37286f7212420656b394f8
https://doi.org/10.1158/1078-0432.22445609
https://doi.org/10.1158/1078-0432.22445609
Autor:
Tero Aittokallio, Matti Poutanen, Sari Mäkelä, Esa Alhoniemi, Mari I. Suominen, Saija Savolainen, Katja Mäkelä, Niina M. Saarinen, Jukka Corander, Teemu D. Laajala
Purpose: Preclinical tumor growth experiments often result in heterogeneous datasets that include growing, regressing, or stable growth profiles in the treatment and control groups. Such confounding intertumor variability may mask the true treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a8a5bd4ec2066f6300fef93b5b3301e
https://doi.org/10.1158/1078-0432.c.6520526.v1
https://doi.org/10.1158/1078-0432.c.6520526.v1
Autor:
Tero Aittokallio, Matti Poutanen, Sari Mäkelä, Esa Alhoniemi, Mari I. Suominen, Saija Savolainen, Katja Mäkelä, Niina M. Saarinen, Jukka Corander, Teemu D. Laajala
PDF file, 134K, Model covariates and results from simulation experiment and probabilistic categorization.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80fda85aa0411177592322ad6000f6ff
https://doi.org/10.1158/1078-0432.22445603
https://doi.org/10.1158/1078-0432.22445603
Autor:
Matias Knuuttila, Riikka Oksala, Teemu D. Laajala, Emrah Yatkin, Seppo Auriola, Saija Savolainen, Matti Poutanen, Sari Mäkelä, Pekka Keski-Rahkonen, Merja R. Häkkinen, Jenny Kallio, Tero Aittokallio
Publikováno v:
American Journal of Pathology. 184(8):2163-2173
Androgens are key factors involved in the development and progression of prostate cancer (PCa), and PCa growth can be suppressed by androgen deprivation therapy. In a considerable proportion of men receiving androgen deprivation therapy, however, PCa
Autor:
Mari I. Suominen, Sari Mäkelä, Matti Poutanen, Teemu D. Laajala, Saija Savolainen, Katja Mäkelä, Esa Alhoniemi, Jukka Corander, Tero Aittokallio, Niina Saarinen
Publikováno v:
Clinical Cancer Research
Purpose: Preclinical tumor growth experiments often result in heterogeneous datasets that include growing, regressing, or stable growth profiles in the treatment and control groups. Such confounding intertumor variability may mask the true treatment
Publikováno v:
The American Journal of Pathology. 171:1013-1022
The role of estrogens in the etiology of prostate cancer is controversial. To demonstrate the specific effects of estrogens and androgens on the development of the prostatic epithelial hyperplasia, we used luteinizing hormone receptor knockout mice (
Autor:
Pooja Talati, Heather L. Montie, Lei Gu, Shilpa Gupta, Elyse Ellsworth, Diane E. Merry, Tuomas Mirtti, Saija Savolainen, Mateusz Koptyra, Ayush Dagvadorj, Feng Shen, Shyh-Han Tan, David T. Hoang, Marja T. Nevalainen, Benjamin E. Leiby, Zhiyong Liao
Although poorly understood, androgen receptor (AR) signaling is sustained despite treatment of prostate cancer with antiandrogens and potentially underlies development of incurable castrate-resistant prostate cancer. However, therapies targeting the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f53da6532024712adfd71e31f9090c36
https://europepmc.org/articles/PMC4456253/
https://europepmc.org/articles/PMC4456253/
Autor:
Jorma J. Palvimo, Mikko Anttonen, JoAnne S. Richards, Olli A. Jänne, Markku Heikinheimo, Saija Savolainen, Venkataraman Sriraman, Sirpa J Hirvonen-Santti
Publikováno v:
Endocrinology. 145:2433-2444
Small nuclear RING finger protein (SNURF/RNF4) is a steroid receptor coregulator that is down-regulated in testicular germ cell cancer. In this work, we examined SNURF expression during murine fetal gonad development and postnatal ovarian folliculoge
Autor:
M. Laine, Saija Savolainen, Hannamari Välimaa, P. Silvoniemi, H. Kujari, Jan-Ake Gustafsson, T. Soukka, Sari Mäkelä
Publikováno v:
Journal of Endocrinology. 180:55-62
Many studies have shown that the oral mucosa and salivary glands are sensitive to estrogen action. However, the expression of estrogen receptors (ERs) within these tissues is an area of controversy. ERs exist as two subtypes (ERalpha and ERbeta), and