Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Saiid Bina"'
Publikováno v:
Critical Care Medicine. 43:584-593
Objective: Malignant hyperthermia is a pharmacogenetic disorder typically triggered by potent inhalation anesthetics and/or the depolarizing muscle relaxant succinylcholine in malignant hyperthermia–susceptible individuals. Since lymphocytes expres
Autor:
Nyamkhishig Sambuughin, Craig G. Carroll, Saiid Bina, Jason J. Longwell, Patricia A. Deuster, Patrick B. Cooper, Susan L. Hamilton, Francis G. O'Connor, Lauren E. Potts, Sheila M. Muldoon, Peter Bedocs, John F. Capacchione
Publikováno v:
A & A Case Reports. 3:23-26
A 30-year-old man developed unexplained rhabdomyolysis, persistently increased creatine kinase and severe debilitating muscle cramps. After a nondiagnostic neurologic evaluation, he was referred for a muscle biopsy, to include histology/histochemistr
Autor:
David A. Fish, Geselle M. McKnight, Kyung H. Kwon, Chester C. Buckenmaier, Saiid Bina, Cynthia Shields, Arthur R. Mielke, John F. Capacchione, Peter Bedocs
Publikováno v:
Anesthesia & Analgesia. 114:894-900
BACKGROUND: Lipid emulsion (20%) is advocated as a rescue drug for local anesthetic toxicity. No study has measured the impact of lipid emulsion therapy on postmortem local anesthetic serum levels. METHODS: We anesthetized Yorkshire swine (n = 11) an
Publikováno v:
Anesthesiology. 113:917-924
Background Malignant hyperthermia susceptibility (MHS) is diagnosed by an invasive in vitro caffeine-halothane contracture test (CHCT) carried out on biopsied skeletal muscle tissue. We are presenting a novel blood test approach for malignant hyperth
Publikováno v:
Anesthesiology. 104:90-100
Background Skeletal muscle fibers from malignant hyperthermia (MH)-susceptible humans and swine are markedly more sensitive to ryanodine receptor (RyR1) agonists than those from normal individuals. Reproducible shifts in the dose-response of skeletal
Publikováno v:
Journal of Laboratory and Clinical Medicine. 133:478-487
The current studies were undertaken to investigate the role of endothelin-1 (ET-1) and its receptors in contractions of isolated pulmonary vessels of the pig induced by diaspirin cross-linked hemoglobin (DCLHb). Second-order pulmonary arteries (PAs)
Autor:
Tarina Wallace, Saiid Bina, Sheila M. Muldoon, Georgirene D. Vladutiu, Cynthia A. Wong, Barbara W. Brandom, Nyamkhishig Sambuughin, Mihaela Visoiu, Paul J. Isackson
Mutations in the ryanodine receptor type 1 gene (RYR1) that encodes the skeletal muscle-specific intracellular calcium (Ca(2+)) release channel are a cause of malignant hyperthermia (MH). In this study, we examined RYR1 mutations in a large number of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40560f9507f7bc3d399783da28c66ccb
https://europepmc.org/articles/PMC3633164/
https://europepmc.org/articles/PMC3633164/
Publikováno v:
Anesthesiology. 85:347-354
Background Halothane and isoflurane previously were reported to attenuate endothelium-derived relaxing factor/nitric oxide-mediated vasodilation and cyclic guanosine monophosphate (cGMP) formation in isolated rat aortic rings. Carbon monoxide has man
Autor:
Edwin W. Lojeski, David L. Wesche, Sheila M. Muldoon, Ben H. Boedeker, Saiid Bina, Duncan H. Haynes, Steven M. Karan
Publikováno v:
Anesthesia & Analgesia. 82:796-802
Dantrolene effectively treats malignant hyperthermia (MH) but the current form, Dantrium®, must be dissolved to a 0.33 mg/mL, pH 9.5 solution. This study describes lecithin-coated microcrystal formulations of sodium dantrolene (MC-NaD) and neutral d
Autor:
Wendy A. Lavezzi, Sheila M. Muldoon, Deanna Steele, John F. Capacchione, Barbara W. Brandom, Nyamkhishig Sambuughin, Saiid Bina
Publikováno v:
Anesthesia and analgesia. 116(2)
A healthy 6-year-old boy developed lower extremity rigidity, trismus, and fever after playing in a splash pool. On arrival in the emergency department, he appeared to be seizing. An endotracheal tube was emergently placed using succinylcholine. Cardi