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pro vyhledávání: '"Saigopal Somasundaram"'
Autor:
Saigopal Somasundaram, Megan E Forrest, Helen Moinova, Allison Cohen, Vinay Varadan, Thomas LaFramboise, Sanford Markowitz, Ahmad M Khalil
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-15 (2018)
Abstract Background DNA methylation is a key epigenetic mark in mammalian organisms that plays key roles in chromatin organization and gene expression. Although DNA methylation in gene promoters is generally associated with gene repression, recent st
Externí odkaz:
https://doaj.org/article/49138478a5ff4b6ea67a6108cb6f0434
Autor:
Anthony Scott, Xiujing Feng, Ahmad M. Khalil, Saigopal Somasundaram, Zhenghe Wang, Peng Zhang, Joseph Willis, Yujun Hao, Yiqing Zhao
Publikováno v:
Oncotarget
Protein tyrosine phosphatase receptor T (PTPRT) is frequently mutated in a variety of human cancers including colorectal cancer. Here we report that PTPRT knockout increases the size of mouse colon tumors in the Apcmin+/- genetic background, suggesti
Autor:
Christine Breindel, Dana M. Valerio, Craig A. Hodges, Lauren Wichman, Saigopal Somasundaram, Ahmad M. Khalil, John R. McCarrey
Publikováno v:
Biology of reproduction. 97(2)
Mammalian reproduction requires that males and females produce functional haploid germ cells through complex cellular differentiation processes known as spermatogenesis and oogenesis, respectively. While numerous studies have functionally characteriz