Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Saida Aarrass"'
Autor:
Maria Ines Ramos, Samuel Garcia, Boy Helder, Saida Aarrass, Kris. A. Reedquist, Sten E. Jacobsen, Paul Peter Tak, Maria Cristina Lebre
Publikováno v:
Journal of Translational Autoimmunity, Vol 3, Iss , Pp 100066- (2020)
Rheumatoid arthritis (RA) is chronic autoimmune disease which etiology remains unknown. Several cell types have been described to potentiate/aggravate the arthritic process however the initiating event in synovial inflammation is still elusive. Dendr
Externí odkaz:
https://doaj.org/article/6cc4c355f63a4d7d982ae53a47f51eb9
Autor:
Saida Aarrass, Boy Helder, Pedro L Vieira, Paul P. Tak, M C Lebre, Thomas Newsom-Davis, Man Wai Tang, Gavin R. Screaton
Publikováno v:
Journal of leukocyte biology, 101(3), 775-783. FASEB
Bone and cartilage destruction is one of the key manifestations of rheumatoid arthritis (RA). Although the role of T helper (Th)17 cells in these processes is clear, the role of IL-21–producing cells T cells has been neglected. We sought to investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::297a49330fd0bd618d3c5afebe1b4ab4
https://pure.amc.nl/en/publications/synovial-il21tnfproducing-cd4-t-cells-induce-joint-destruction-in-rheumatoid-arthritis-by-inducing-matrix-metalloproteinase-production-by-fibroblastlike-synoviocytes(d1bd9548-8f27-498b-a444-4291f69f3b35).html
https://pure.amc.nl/en/publications/synovial-il21tnfproducing-cd4-t-cells-induce-joint-destruction-in-rheumatoid-arthritis-by-inducing-matrix-metalloproteinase-production-by-fibroblastlike-synoviocytes(d1bd9548-8f27-498b-a444-4291f69f3b35).html
Backgroundand objectives Autoimmune diseases often result from inappropriate or unregulated activation of autoreactive T cells. The induction and maintenance of T cell tolerance to tissue antigens is essential to prevent autoimmunity. Combinations of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dba15776e24652272218cfe1c4aa3c8e
https://doi.org/10.1136/annrheumdis-2011-201234.12
https://doi.org/10.1136/annrheumdis-2011-201234.12
Autor:
M C Lebre, Saida Aarrass, Olga N. Karpus, M I Ramos, Sten Eirik W. Jacobsen, Paul P. Tak, P. Broekstra
Publikováno v:
Annals of the rheumatic diseases, 74(1), 211-219. BMJ Publishing Group
ObjectiveComprehending the mechanisms that regulate activation of autoreactive T cells and B cell antibody production is fundamental for understanding the breakdown in self-tolerance and development of autoimmunity. Here we studied the role of Fms-li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ef0afd6fe3e35b2dacaf971f79e47b2
https://ora.ox.ac.uk/objects/uuid:9df6562d-11e0-4e8e-8b94-e967595046ee
https://ora.ox.ac.uk/objects/uuid:9df6562d-11e0-4e8e-8b94-e967595046ee
Autor:
Maria J. H. de Hair, Boy Helder, Arno W R van Kuijk, M I Ramos, Danielle M. Gerlag, Marcel B. M. Teunissen, M C Lebre, Saida Aarrass, Paul P. Tak
Publikováno v:
Rheumatology (Oxford, England), 55(9), 1575-1584. Oxford University Press
We aimed to investigate the early changes in expression of C-type lectin domain family 9, member A (CLEC9A), a C-type lectin that is specifically expressed by the CD141(+) dendritic cell subset that is involved in cross-presentation to CD8(+) T cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fdb6bf062314ace71e858ba129825f7
https://pubmed.ncbi.nlm.nih.gov/27179104
https://pubmed.ncbi.nlm.nih.gov/27179104
Autor:
Massimo Pinzani, Piter J. Bosma, Willem Boers, Ronald P.J. Oude Elferink, Chris Linthorst, Saida Aarrass
Publikováno v:
Journal of Biological Chemistry. 281:16289-16295
Activated hepatic stellate cells (HSC) that transdifferentiate to myofibroblasts in the injured liver are responsible for scar formation that leads to fibrosis and eventually cirrhosis. To investigate the gene expression profile during different stag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2fec0c07cb57fa7b22924c4691ef7f36
https://doi.org/10.1074/jbc.m600711200
https://doi.org/10.1074/jbc.m600711200
Autor:
Pleun Broekstra, Boy Helder, Saida Aarrass, Kris A. Reedquist, Paul P. Tak, M C Lebre, M I Ramos, Daan M Gerlag, Samuel Garcia Perez
Publikováno v:
Arthritis research & therapy, 15(6). BioMed Central
Arthritis Research & Therapy
Arthritis Research & Therapy
Introduction The FMS-related tyrosine kinase 3 ligand (Flt3L)/CD135 axis plays a fundamental role in proliferation and differentiation of dendritic cells (DCs). As DCs play an important role in rheumatoid arthritis (RA) immunopathology we studied in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a03748d098f3063813a4766746820898
https://pure.amc.nl/en/publications/fmsrelated-tyrosine-kinase-3-ligand-flt3lcd135-axis-in-rheumatoid-arthritis(3777b68b-6ef7-4db3-90fc-fb14ea45cb45).html
https://pure.amc.nl/en/publications/fmsrelated-tyrosine-kinase-3-ligand-flt3lcd135-axis-in-rheumatoid-arthritis(3777b68b-6ef7-4db3-90fc-fb14ea45cb45).html
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, Vol 9, Iss Suppl 2, p P49 (2011)
Journal of Translational Medicine, Vol 9, Iss Suppl 2, p P49 (2011)
Background Rheumatoid arthritis (RA) is characterized by inflammation and hyperplasia of the synovial membrane which ultimately results in erosion of cartilage and bone. Fibroblast-like synoviocytes (FLS) play ac ritical role in this destructive proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edb3ea49892601f925650bd23aeed532
https://doi.org/10.1186/1479-5876-9-s2-p49
https://doi.org/10.1186/1479-5876-9-s2-p49
Autor:
Ana S. F. Oliveira, Saida Aarrass, Paul P. Tak, Tim Wyant, Richard Horuk, Kris A. Reedquist, Clarissa E. Vergunst, M C Lebre, IY Choi
Publikováno v:
PLoS ONE, 6(7). Public Library of Science
PLoS ONE, Vol 6, Iss 7, p e21772 (2011)
PLoS ONE
PLoS ONE, Vol 6, Iss 7, p e21772 (2011)
PLoS ONE
BACKGROUND: The aim of this study was to provide more insight into the question as to why blockade of CCR1, CCR2, and CCR5 may have failed in clinical trials in rheumatoid arthritis (RA) patients, using an in vitro monocyte migration system model. ME
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::927019c0c3f0c30a1055bfff4fca38a0
https://pure.amc.nl/en/publications/why-ccr2-and-ccr5-blockade-failed-and-why-ccr1-blockade-might-still-be-effective-in-the-treatment-of-rheumatoid-arthritis(b3a66dcc-67d3-4e01-95e0-06d2440ca629).html
https://pure.amc.nl/en/publications/why-ccr2-and-ccr5-blockade-failed-and-why-ccr1-blockade-might-still-be-effective-in-the-treatment-of-rheumatoid-arthritis(b3a66dcc-67d3-4e01-95e0-06d2440ca629).html
Autor:
Willem, Boers, Saida, Aarrass, Chris, Linthorst, Massimo, Pinzani, Ronald Oude, Elferink, Piter, Bosma
Publikováno v:
The Journal of biological chemistry. 281(24)
Activated hepatic stellate cells (HSC) that transdifferentiate to myofibroblasts in the injured liver are responsible for scar formation that leads to fibrosis and eventually cirrhosis. To investigate the gene expression profile during different stag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::586224159ae0a6cc9206c61f703d5ee9
https://pubmed.ncbi.nlm.nih.gov/16606614
https://pubmed.ncbi.nlm.nih.gov/16606614