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Akademický článek

Vorolanib, sunitinib, and axitinib: A comparative study of vascular endothelial growth factor receptor inhibitors and their anti-angiogenic effects.

Autor: Sophie J Bakri, Jeff Lynch, Michelle Howard-Sparks, Stephan Saint-Juste, Said Saim

Publikováno v: PLoS ONE, Vol 19, Iss 6, p e0304782 (2024)

PurposePathological angiogenesis and vascular instability are observed in diabetic retinopathy (DR), diabetic macular edema (DME), and wet age-related macular degeneration (wAMD). Many receptor tyrosine kinases (RTKs) including vascular endothelial g

Externí odkaz: https://doaj.org/article/e5eded1288454c548d83df2d9b1a8013

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ARABE-BARBE HORSE’S SPERM MOTILITY IMPROVEMENT USING HONEY

Autor: Fatima Zohra Demni, Mohamed Amine Ayad, Sofiane Derrar, Mohamed Said Saim, Samia Meliani

Publikováno v: International Journal of Ecosystems and Ecology Science (IJEES). 9:799-802

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::209ed8c42a56d05aea4710486dcdc600
https://doi.org/10.31407/ijees9426

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In Vitro Drug Release After Crushing: Evaluation of Xtampza® ER and Other ER Opioid Formulations

Autor: Said Saim, Stephen P. Mayock, Alison B. Fleming

Publikováno v: Clinical Drug Investigation

Background and Objective Extended-release (ER) opioids are associated with high rates of abuse. Recreational opioid users often manipulate ER formulations to achieve a high plasma concentration in a short amount of time, resulting in a more rapid and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33a92b9d6fea5525c894ba3be2c16088
https://doi.org/10.1007/s40261-017-0561-9

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Impact of physical manipulation on in vitro and in vivo release profiles of oxycodone DETERx®: An extended-release, abuse-deterrent formulation

Autor: Michael Grima, Stephen P. Mayock, Said Saim, Ernest A. Kopecky, Ravi K. Varanasi, Alison B. Fleming, Patrick K. Noonan

Publikováno v: Journal of Opioid Management. 10:233-246

Objective: In vitro: To assess the effect of common crushing techniques on particle size reduction (PSR) and in vitro drug-release kinetics of oxycodone DETERx® (herein DETERx) and of a commercially available oxycodone extended-release (ER) tablet.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1fe6755daf7cad286f8079b26d8e57c
https://doi.org/10.5055/jom.2014.0211

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Response to Crudele et al. Commentary on Mayock et al. 'In Vitro Drug Release after Crushing: Evaluation of Xtampza® ER and Other ER Opioid Formulations'

Autor: Said Saim, Alison B. Fleming, Stephen P. Mayock

Publikováno v: Clinical Drug Investigation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01a508d37ddeca100acd5f6d0c0d2c7c
http://europepmc.org/articles/PMC6061363

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Akademický článek

COMPARISON BETWEEN CYTOLOGY AND HISTOPATHOLOGY TO EVALUATE ENDOMETRITIS IN DAIRY COWS.

Autor: Sofiane, Derrar, Ayad, Mohamed Amine, Samia, Meliani, Houari, Hemida, Said, Saim Mohamed, Safer, Imen

Publikováno v: International Journal of Ecosystems & Ecology Sciences; Mar-Jun2020, Vol. 10 Issue 2, p265-270, 6p

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A Practical Method for the Removal of Ruthenium Byproducts by Supercritical Fluid Extraction

Autor: Fabrice Gallou, Steve T. Horhota, Said Saim, David Joseph Bochniak, and Nathan K. Yee, Koenig Kenneth J, Chris H. Senanayake

Publikováno v: Organic Process Research & Development. 10:937-940

Supercritical CO2 was used to remove ruthenium catalyst and its derived by-products from a crude ring-closing metathesis reaction. The method was implemented in a semi-continuous fashion and allowed for efficient removal of the toxic metal impurities

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8e0c0c3f96375f4b364fa82738c0b4b5
https://doi.org/10.1021/op0601114

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Author Correction to: In Vitro Drug Release After Crushing: Evaluation of Xtampza® ER and Other ER Opioid Formulations

Autor: Stephen P. Mayock, Said Saim, Alison B. Fleming

Publikováno v: Clinical Drug Investigation. 37:1203-1203

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ca17596d95d0921ade98981f83af032
https://doi.org/10.1007/s40261-017-0599-8

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Evaluation of an Extended-Release, Abuse-Deterrent, Microsphere-in-Capsule Analgesic for the Management of Patients with Chronic Pain With Dysphagia (CPD)

Autor: Ernest A. Kopecky, Said Saim, Douglas R. Carlson, Ravi K. Varanasi, Michael Grima, Alison B. Fleming, Stephen P. Mayock

Publikováno v: Pain practice : the official journal of World Institute of Pain. 16(3)

Background Patients who have chronic pain with dysphagia (difficulty swallowing) (CPD) often have difficulty taking oral medication and, as such, alter their medications by crushing or chewing in an attempt to make it easier to swallow. Such manipula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb04d7ad17ceacfe8c9a6616b2359fd8
https://pubmed.ncbi.nlm.nih.gov/25639548

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Fullerene-linked particles as LC chromatographic media and modification of their electron donor/acceptor properties by secondary chemical reactions

Autor: Congyuan Guo, Kenneth C. Kuo, David L. Stalling, Said Saim

Publikováno v: Journal of Microcolumn Separations. 5:223-235

Fullerenes (C60 and C70) linked to small silica or polymer particles provide novel chromatographic stationary phases with electron donor/acceptor surface interactions that may parallel those of aromatic carbons. Separations of fullerenes and aromatic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9e413a85310bb17b39c86abc03921934
https://doi.org/10.1002/mcs.1220050307

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