Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Said Lyoumi"'
Autor:
Emmanuel Richard, Pierre Costet, Said Lyoumi, Cécile Ged, Thibaud Lefebvre, Magalie Lalanne, Hervé Puy, Zoubida Karim, Hubert de Verneuil, François Moreau-Gaudry, Isabelle Lamrissi-Garcia, Jean-Marc Blouin, Sarah Millot, Laurent Gouya
Publikováno v:
Biochemical and Biophysical Research Communications
Biochemical and Biophysical Research Communications, Elsevier, 2019, 520 (2), pp.297-303. ⟨10.1016/j.bbrc.2019.09.141⟩
Biochemical and Biophysical Research Communications, Elsevier, 2019, 520 (2), pp.297-303. ⟨10.1016/j.bbrc.2019.09.141⟩
Clinical severity is heterogeneous among patients suffering from congenital erythropoietic porphyria (CEP) suggesting a modulation of the disease (UROS deficiency) by environmental factors and modifier genes. A KI model of CEP due to a missense mutat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010dc36afaeb6d36505f7554a92cdc2c
https://pubmed.ncbi.nlm.nih.gov/31601421
https://pubmed.ncbi.nlm.nih.gov/31601421
Autor:
Dimitri Tchernitchko, Laurent Gouya, Said Lyoumi, Nicolas Pallet, Jérôme Lamoril, Caroline Schmitt, Quentin Tavernier, Hervé Puy, Eric Thervet, Alexandre Karras, Neila Talbi, Zoubida Karim, A. M. Robreau
Publikováno v:
Journal of the American Society of Nephrology. 28:1924-1932
CKD occurs in most patients with acute intermittent porphyria (AIP). During AIP, δ-aminolevulinic acid (ALA) accumulates and promotes tubular cell death and tubulointerstitial damage. The human peptide transporter 2 (PEPT2) expressed by proximal tub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34d91536bdba01aa1c6949b440da7a66
https://doi.org/10.1681/asn.2016080918
https://doi.org/10.1681/asn.2016080918
Publikováno v:
Clinics and Research in Hepatology and Gastroenterology. 39:412-425
The hereditary porphyrias comprise a group of eight metabolic disorders of the heme biosynthesis pathway. Each porphyria is caused by abnormal function at a separate enzymatic step resulting in a specific accumulation of heme precursors. Porphyrias a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58fb66e618125aeaa2961efa5da6c5f6
https://doi.org/10.1016/j.clinre.2015.05.009
https://doi.org/10.1016/j.clinre.2015.05.009
Autor:
Katell Peoc'h, Joëlle Marie, Carole Beaumont, Bernard Grandchamp, Hervé Puy, Zoubida Karim, Caroline Schmitt, Jean-Charles Deybach, Laurent Gouya, Hubert de Verneuil, François Moreau-Gaudry, Arienne Mirmiran, Said Lyoumi, Rima Soaid, Véronique Guyonnet-Dupérat, Vincent Oustric, Sarah Ducamp, Hana Manceau
Publikováno v:
The American Journal of Human Genetics. 94:611-617
In 90% of people with erythropoietic protoporphyria (EPP), the disease results from the inheritance of a common hypomorphic FECH allele, encoding ferrochelatase, in trans to a private deleterious FECH mutation. The activity of the resulting FECH enzy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a41ebf4b53c3f5c1c1bc94b847871b0
https://doi.org/10.1016/j.ajhg.2014.02.010
https://doi.org/10.1016/j.ajhg.2014.02.010
Autor:
Gloria C. Ferreira, Said Lyoumi, Carmen Herrero, Hervé Puy, Laurent Gouya, Cécile Ged, Celia Badenas, Carole Beaumont, Constance Delaby, Hubert de Verneuil, Jordi To-Figueras, Jean-Charles Deybach, Jerome Clayton, Sarah Ducamp
Publikováno v:
Blood. 118:1443-1451
Mutations in the uroporphyrinogen III synthase (UROS) gene cause congenital erythropoietic porphyria (CEP), an autosomal-recessive inborn error of erythroid heme biosynthesis. Clinical features of CEP include dermatologic and hematologic abnormalitie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b529d263db12073888592620d582991
https://doi.org/10.1182/blood-2011-03-342873
https://doi.org/10.1182/blood-2011-03-342873
Autor:
Valérie Andrieu, Sarah Millot, Carole Beaumont, Zoubida Karim, Margarita Hurtado-Nedelec, Said Lyoumi, Philippe Lettéron, Sigismond Lasocki, Samira Bennada, J L Charrier, Olivier Thibaudeau
Publikováno v:
Blood. 116:6072-6081
Mouse bone marrow erythropoiesis is homeostatic, whereas after acute anemia, bone morphogenetic protein 4 (BMP4)–dependent stress erythropoiesis develops in the spleen. The aim of this work was to compare spleen stress erythropoiesis and bone marro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fcc44c052038ce574e4d7c7bf10ef7f
https://doi.org/10.1182/blood-2010-04-281840
https://doi.org/10.1182/blood-2010-04-281840
Autor:
Bruno Galy, Matthias W. Hentze, Sylvia Kaden, Hervé Puy, Hermann Josef Gröne, Sven W. Sauer, Said Lyoumi, Dunja Ferring-Appel, Stefan Kölker
Publikováno v:
Cell Metabolism. 12:194-201
SummaryMitochondria supply cells with ATP, heme, and iron sulfur clusters (ISC), and mitochondrial energy metabolism involves both heme- and ISC-dependent enzymes. Here, we show that mitochondrial iron supply and function require iron regulatory prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9ff170bcb52b2c30b82bd267ed66662
https://doi.org/10.1016/j.cmet.2010.06.007
https://doi.org/10.1016/j.cmet.2010.06.007
Publikováno v:
Chronobiology International. 25:851-867
The main porphyrin in rodent Harderian glands (HGs) is the heme precursor protoporphyrin IX (PPIX). Rhythmic variations in PPIX levels have yet to be studied in rodent HGs. Moreover, the mode of regulation of heme biosynthesis in this organ is poorly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93ce0940efde5eb79da8c17bdaea929d
https://doi.org/10.1080/07420520802548242
https://doi.org/10.1080/07420520802548242
Hepcidin as a Major Component of Renal Antibacterial Defenses against Uropathogenic Escherichia coli
Autor:
Dounia Houamel, Philippe Lettéron, Hervé Puy, Alain Vandewalle, Sarah Millot, Marie-Agnès Sari, Erick Denamur, Sophie Vaulont, Said Lyoumi, Carole Beaumont, Thibaud Lefebvre, Zoubida Karim, Boualem Moulouel, Nicolas Ducrot, Raed Daher, Odile Bouvet, Jerome Tourret, Laurent Gouya
The iron-regulatory peptide hepcidin exhibits antimicrobial activity. Having previously shown hepcidin expression in the kidney, we addressed its role in urinary tract infection (UTI), which remains largely unknown. Experimental UTI was induced in wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2896c96d2a20a9ecec20eb24cce3d9db
https://europepmc.org/articles/PMC4769187/
https://europepmc.org/articles/PMC4769187/
Autor:
Jean-Charles Deybach, Laurent Gouya, Jérôme Lamoril, Jean-Michel Camadro, Christian Rose, Said Lyoumi, Vasco Da Silva, E. Malonova, Catherine Boileau, Hervé Puy, Carole Beaumont, Bernard Grandchamp, Caroline Schmitt, Magali Flamme
Publikováno v:
Human Molecular Genetics
Human Molecular Genetics, Oxford University Press (OUP), 2005, 14, pp.3089-3098. ⟨10.1093/hmg/ddi342⟩
Human Molecular Genetics, Oxford University Press (OUP), 2005, 14, pp.3089-3098. ⟨10.1093/hmg/ddi342⟩
Hereditary coproporphyria (HCP), an autosomal dominant acute hepatic porphyria, results from mutations in the gene that encodes coproporphyrinogen III oxidase (CPO). HCP (heterozygous or rarely homozygous) patients present with an acute neurovisceral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca603e3c90a5a9b94114eaa18db6cbaf
https://doi.org/10.1093/hmg/ddi342
https://doi.org/10.1093/hmg/ddi342