Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Said Oumouch"'
Autor:
Marie-Pierre de Béthune, Said Oumouch, Patrice Palandjian, Jerome Emile Georges Guillemont, Daniel Vernier, Kurt Hertogs, Koen Andries, Chi Hung Nguyen, Laurence Queguiner, David S. Grierson, Abdellah Benjahad, Laurence F B Decrane
Publikováno v:
Journal of medicinal chemistry
A series of C-5 methyl substituted 4-arylthio- and 4-aryloxy-3-iodopyridin-2(1H)-ones has been synthesized as new pyridinone analogues for their evaluation as anti-HIV inhibitors. The optimization at the 5-position was developed through an efficient
Publikováno v:
Molecular Diversity. 10:429-434
An efficient method for preparation of 4,6 or 5,6 disubstituted 3-aminopyridazines was easily carried out starting from easily available 4-bromo-pyridazine-3,6-dione, and using combination of both amination and Pd(0) cross-coupling reactions under mi
Publikováno v:
Current Organic reactions
Current Organic reactions, 2006, 10, pp.277-295
Current Organic reactions, 2006, 10, pp.277-295
Autor:
Chi Hung Nguyen, Edward Arnold, Alain Philippe Poncelet, David Grierson, Stephen H. Hughes, Daniel M. Himmel, Said Oumouch, Christophe Meyer, Sophie Coupa, Jerome Guillemont, Abdellah Benjahad, Koen Andries, Kalyan Das, Arthur D. Clark, Csoka Imre Christian Francis
Publikováno v:
Journal of medicinal chemistry
In the treatment of AIDS, the efficacy of all drugs, including non-nucleoside inhibitors (NNRTIs) of HIV-1 reverse transcriptase (RT), has been limited by the rapid appearance of drug-resistant viruses. Lys103Asn, Tyr181Cys, and Tyr188Leu are some of
Autor:
Chi Hung Nguyen, Elisabeth Thérèse Jeanne Pasquier, Dominique Jean-Pierre Mabire, Koen Andries, Jerome Emile Georges Guillemont, Abdellah Benjahad, David S. Grierson, Said Oumouch
Publikováno v:
Bioorganic and medicinal chemistry letters
Bioorganic and Medicinal Chemistry Letters
Bioorganic and Medicinal Chemistry Letters, Elsevier, 2007, 17 (3), pp.712-6. ⟨10.1016/j.bmcl.2006.10.082⟩
Bioorganic and Medicinal Chemistry Letters
Bioorganic and Medicinal Chemistry Letters, Elsevier, 2007, 17 (3), pp.712-6. ⟨10.1016/j.bmcl.2006.10.082⟩
As part of a systematic SAR study on the 3-iodo-4-phenoxypyridinone 3 (IOPY) type non-nucleoside reverse transcriptase inhibitors, the analogues 4a-4z bearing different C-3 substituents were synthesized and evaluated for their anti-HIV activity again
Publikováno v:
SYNTHESIS
SYNTHESIS, Georg Thieme Verlag, 2005, pp.25-27
SYNTHESIS, Georg Thieme Verlag, 2005, pp.25-27
2-Thiomethylimidazolin-5-one undergoes efficient palladium-catalyzed cross-coupling with boronic acids and organostannanes mediated by copper(I) thiophene-2-carboxylate.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32b6e0f96e6fbc2342d255c1ac15e994
https://hal.archives-ouvertes.fr/hal-00129953
https://hal.archives-ouvertes.fr/hal-00129953
Autor:
Jérôme Guillemont, Abdellah Benjahad, Said Oumouch, Laurence Decrane, Patrice Palandjian, Daniel Vernier, Laurence Queguiner, Koen Andries, Marie-Pierre de Béthune, Kurt Hertogs, David S. Grierson, Chi Hung Nguyen
Publikováno v:
Journal of Medicinal Chemistry; Dec2009, Vol. 52 Issue 23, p7473-7487, 15p