Resistance of Omicron subvariants BA.2.75.2, BA.4.6, and BQ.1.1 to neutralizing antibodies

Autor: Delphine Planas, Timothée Bruel, Isabelle Staropoli, Florence Guivel-Benhassine, Françoise Porrot, Piet Maes, Ludivine Grzelak, Matthieu Prot, Said Mougari, Cyril Planchais, Julien Puech, Madelina Saliba, Riwan Sahraoui, Florent Fémy, Nathalie Morel, Jérémy Dufloo, Rafael Sanjuán, Hugo Mouquet, Emmanuel André, Laurent Hocqueloux, Etienne Simon-Loriere, David Veyer, Thierry Prazuck, Hélène Péré, Olivier Schwartz

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)

In this work, Planas et al. report that Omicron subvariants BA.2.75.2, BA.4.6, and BQ.1.1 escape neutralization from monoclonal antibodies, and sera from vaccinated individuals with or without Omicron BA.1/2 or BA.5 breakthrough infection.

Externí odkaz: https://doaj.org/article/9c8be56ed653485d87b24ff59791518f

Role of the R349 Gene and Its Repeats in the MIMIVIRE Defense System

Autor: Said Mougari, Jonatas Abrahao, Graziele P. Oliveira, Jacques Y. Bou Khalil, Bernard La Scola

Publikováno v: Frontiers in Microbiology, Vol 10 (2019)

MIMIVIRE is a defense system described in lineage A Mimivirus (Mimiviridae family) that mediates resistance against Zamilon virophage. It is composed of putative helicase and nuclease associated with a gene of unknown function called R349, which cont

Externí odkaz: https://doaj.org/article/ef3478dff91f4c9a8825cb890442bec2

Resistance of Omicron subvariants BA.2.75.2, BA.4.6 and BQ.1.1 to neutralizing antibodies

Autor: Delphine Planas, Timothée Bruel, Isabelle Staropoli, Florence Guivel-Benhassine, Françoise Porrot, Piet Maes, Ludivine Grzelak, Matthieu Prot, Said Mougari, Cyril Planchais, Julien Puech, Madelina Saliba, Riwan Sahraoui, Florent Fémy, Nathalie Morel, Jérémy Dufloo, Rafael Sanjuán, Hugo Mouquet, Emmanuel André, Laurent Hocqueloux, Etienne Simon-Loriere, David Veyer, Thierry Prazuck, Hélène Péré, Olivier Schwartz

Publikováno v: bioRxiv : the preprint server for biology
bioRxiv : the preprint server for biology, 2022, ⟨10.1101/2022.11.17.516888⟩
Nature Communications
Nature Communications, 2023, 14 (1), pp.824. ⟨10.1038/s41467-023-36561-6⟩

Convergent evolution of SARS-CoV-2 Omicron BA.2, BA.4 and BA.5 lineages has led to the emergence of several new subvariants, including BA.2.75.2, BA.4.6. and BQ.1.1. The subvariants BA.2.75.2 and BQ.1.1 are expected to become predominant in many coun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56b236de1cc39227143ac90e110183ff
https://hal-pasteur.archives-ouvertes.fr/pasteur-04082579

Discovery and Further Studies on Giant Viruses at the IHU Mediterranee Infection That Modified the Perception of the Virosphere

Autor: Clara Rolland, Julien Andreani, Amina Cherif Louazani, Sarah Aherfi, Rania Francis, Rodrigo Rodrigues, Ludmila Santos Silva, Dehia Sahmi, Said Mougari, Nisrine Chelkha, Meriem Bekliz, Lorena Silva, Felipe Assis, Fábio Dornas, Jacques Yaacoub Bou Khalil, Isabelle Pagnier, Christelle Desnues, Anthony Levasseur, Philippe Colson, Jônatas Abrahão, Bernard La Scola

Publikováno v: Viruses, Vol 11, Iss 4, p 312 (2019)

The history of giant viruses began in 2003 with the identification of Acanthamoeba polyphaga mimivirus. Since then, giant viruses of amoeba enlightened an unknown part of the viral world, and every discovery and characterization of a new giant virus

Externí odkaz: https://doaj.org/article/fb5f176695614356a78823525497b1d1

A virophage cross-species infection through mutant selection represses giant virus propagation, promoting host cell survival

Autor: Fabrizio Di Pinto, Philippe Colson, Bernard La Scola, Said Mougari, Jônatas Santos Abrahão, Dehia Sahmi-Bounsiar, Nisrine Chelkha

Publikováno v: Communications Biology
Communications Biology, Nature Publishing Group, 2020, 3 (1), ⟨10.1038/s42003-020-0970-9⟩
Communications Biology, 2020, 3 (1), ⟨10.1038/s42003-020-0970-9⟩
Communications Biology, Vol 3, Iss 1, Pp 1-13 (2020)

Virus adaptation to new hosts is a major cause of infectious disease emergence. This mechanism has been intensively studied in the context of zoonotic virus spillover, due to its impact on global health. However, it remains unclear for virophages, pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02b5ddff2ea11608688cfd68f0120add