Bioassay-guided isolation and in Silico characterization of cytotoxic compounds from Hemimycale sp. Sponge targeting A549 lung cancer cells.

Autor: Said, Asmaa Abo Elgoud¹ (AUTHOR), Abdel-Rahman, Islam M.² (AUTHOR), Mostafa, Yaser A.³ (AUTHOR), Attia, Eman Zekry¹ (AUTHOR), Samy, Mamdouh Nabil¹ (AUTHOR), Abdelmohsen, Usama Ramadan^1,4 (AUTHOR) usama.ramadan@mu.edu.eg, Matsunami, Katsuyoshi⁵ (AUTHOR), Fouad, Mostafa A.¹ (AUTHOR), Gouda, Yaser G.⁶ (AUTHOR)

Publikováno v: BMC Chemistry. 11/1/2024, Vol. 18 Issue 1, p1-10. 10p.

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Niosomes as promising approach for enhancing the cytotoxicity of Hemimycale sp. total crude extract supported with in-silico studies.

Autor: Said AAE; Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia, 61519, Egypt., Mahmoud BK; Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia, 61519, Egypt., Helmy AM; Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Deraya University, Minya, Egypt.; Pharmaceutical Engineering and 3D Printing (PharmE3D) Lab, Division of Molecular Pharmaceutics and Drug Delivery, College of Pharmacy, The University of Texas at Austin, Austin, TX, 78712, USA., Mohamed NM; Pharmaceutical Chemistry Department, Modern University for Technology and Information (MTI), Cairo, Egypt., Attia EZ; Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia, 61519, Egypt., Samy MN; Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia, 61519, Egypt., Abdelmohsen UR; Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia, 61519, Egypt. usama.ramadan@mu.edu.eg.; Department of Pharmacognosy, Faculty of Pharmacy, Deraya University, Universities Zone, New Minia City, 61111, Egypt. usama.ramadan@mu.edu.eg., Fouad MA; Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia, 61519, Egypt.

Publikováno v: Scientific reports [Sci Rep] 2024 Jan 31; Vol. 14 (1), pp. 2546. Date of Electronic Publication: 2024 Jan 31.