Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sai-Tim Ho"'
Publikováno v:
Cell & Bioscience, Vol 9, Iss 1, Pp 1-12 (2019)
Abstract Background Telomere maintenance is an important factor in tumorigenesis. PinX1 is a potent telomerase regulator which also involves in telomerase loading to telomeres. Nucleophosmin (NPM) can partially attenuate PinX1 inhibition of telomeras
Externí odkaz:
https://doaj.org/article/7ae333f27a514e75815ad0a28627270e
Autor:
Zhan-Fang Fan, Sai-Tim Ho, Rui Wen, Ya Fu, Lei Zhang, Jian Wang, Chun Hu, Pang-Chui Shaw, Yang Liu, Mao-Sheng Cheng
Publikováno v:
Molecules, Vol 24, Iss 17, p 3180 (2019)
Based on the structural scaffolds of natural products, two series of flavonoid derivatives, for a total of twelve compounds, were designed and synthesized as potential human telomerase inhibitors. Using a modified TRAP-PCR assay, compound 5c exhibite
Externí odkaz:
https://doaj.org/article/80fe24d922bf402fb352b6d091e38b55
Autor:
Chun Hu, Jian Wang, Rui Wen, Zhan-Fang Fan, Yang Liu, Lei Zhang, Ya Fu, Pang-Chui Shaw, Maosheng Cheng, Sai-Tim Ho
Publikováno v:
Molecules, Vol 24, Iss 17, p 3180 (2019)
Molecules
Volume 24
Issue 17
Molecules
Volume 24
Issue 17
Based on the structural scaffolds of natural products, two series of flavonoid derivatives, for a total of twelve compounds, were designed and synthesized as potential human telomerase inhibitors. Using a modified TRAP-PCR assay, compound 5c exhibite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48f4f8cd417a7b6b03534c305cf65290
https://www.mdpi.com/1420-3049/24/17/3180
https://www.mdpi.com/1420-3049/24/17/3180
Publikováno v:
Cell & Bioscience
Cell & Bioscience, Vol 9, Iss 1, Pp 1-12 (2019)
Cell & Bioscience, Vol 9, Iss 1, Pp 1-12 (2019)
Background Telomere maintenance is an important factor in tumorigenesis. PinX1 is a potent telomerase regulator which also involves in telomerase loading to telomeres. Nucleophosmin (NPM) can partially attenuate PinX1 inhibition of telomerase activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9617ec1015790b3498f3ed35fb44f22d
http://europepmc.org/articles/PMC6567508
http://europepmc.org/articles/PMC6567508
Additional file 1. Correlation Analysis for Immunofluorescence Images. Degree of colocalization between proteins expressed as Pearsonâ s correlation coefficient of the two immunofluorescence signals.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c041cf7010f7d11a3b8b0191acd9643
