Zobrazeno 1 - 10
of 533
pro vyhledávání: '"Sai Wah, Tsao"'
Autor:
Lanqi Gong, Jie Luo, Yu Zhang, Yuma Yang, Shanshan Li, Xiaona Fang, Baifeng Zhang, Jiao Huang, Larry Ka-Yue Chow, Dittman Chung, Jinlin Huang, Cuicui Huang, Qin Liu, Lu Bai, Yuen Chak Tiu, Pingan Wu, Yan Wang, George Sai-Wah Tsao, Dora Lai-wan Kwong, Anne Wing-Mui Lee, Wei Dai, Xin-Yuan Guan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-24 (2023)
Response rates to immunotherapies in patients with nasopharyngeal carcinoma (NPC) are still limited. Here the authors show that tumor-restricted CD70 correlates with regulatory T cell abundance and suppressive activity in NPC and that CD70 blockade i
Externí odkaz:
https://doaj.org/article/b6da0bb5eab74ad7aa459a56759ab2ba
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 7, Pp 718-730 (2021)
EGFR signaling promotes ovarian cancer tumorigenesis, and high EGFR expression correlates with poor prognosis. However, EGFR inhibitors alone have demonstrated limited clinical benefit for ovarian cancer patients, owing partly to tumor resistance and
Externí odkaz:
https://doaj.org/article/62e3575faa854441946ab8b31767042e
Autor:
Jeff P. Bruce, Ka-Fai To, Vivian W. Y. Lui, Grace T. Y. Chung, Yuk-Yu Chan, Chi Man Tsang, Kevin Y. Yip, Brigette B. Y. Ma, John K. S. Woo, Edwin P. Hui, Michael K. F. Mak, Sau-Dan Lee, Chit Chow, Sharmila Velapasamy, Yvonne Y. Y. Or, Pui Kei Siu, Samah El Ghamrasni, Stephenie Prokopec, Man Wu, Johnny S. H. Kwan, Yuchen Liu, Jason Y. K. Chan, C. Andrew van Hasselt, Lawrence S. Young, Christopher W. Dawson, Ian C. Paterson, Lee-Fah Yap, Sai-Wah Tsao, Fei-Fei Liu, Anthony T. C. Chan, Trevor J. Pugh, Kwok-Wai Lo
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The genomic characterisation of nasopharyngeal carcinoma (NPC) remains crucial. Here, the authors perform whole-genome sequencing for 70 NPCs with EBV gene expression, report the somatic alterations and EBV-mediated effects converging on NF-κB activ
Externí odkaz:
https://doaj.org/article/84b65b92c11446b886dec64811b68199
Autor:
Dongdong Yan, Di Cui, Yun Zhu, Cecilia Ka Wing Chan, Chung Hang Jonathan Choi, Tengfei Liu, Sai Wah Tsao, Stephanie Ma, Annie Lai Man Cheung
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 8, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/83c8d19e1a26413481cd6accad462cc0
Autor:
Matt Lechner, Volker H. Schartinger, Christopher D. Steele, Wen Long Nei, Marc Lucas Ooft, Liesa-Marie Schreiber, Christodoulos P. Pipinikas, Grace Tin-Yun Chung, Yuk Yu Chan, Feng Wu, Ka-Fai To, Chi Man Tsang, Wayne Pearce, Daniele Morelli, Martin Philpott, Liam Masterson, Reshma Nibhani, Graham Wells, Christopher G. Bell, Julia Koller, Susanne Delecluse, Yim Ling Yip, Jacklyn Liu, Cillian T. Forde, Martin D. Forster, Amrita Jay, József Dudás, Annika Krapp, Simon Wan, Christian Uprimny, Susanne Sprung, Johannes Haybaeck, Tim R. Fenton, Kerry Chester, Christina Thirlwell, Gary Royle, Teresa Marafioti, Rajeev Gupta, Sagung Rai Indrasari, Camelia Herdini, Mohd Afiq Mohd Slim, I. Indrawati, Liam Sutton, Renske Fles, Bing Tan, Joe Yeong, Amit Jain, Shuting Han, Haitao Wang, Kelvin S. H. Loke, Wan He, Ruilian Xu, Hongtao Jin, Zhiqiang Cheng, David Howard, Peter H. Hwang, Quynh-Thu Le, Joshua K. Tay, Robert B. West, Sai Wah Tsao, Tim Meyer, Herbert Riechelmann, Udo Oppermann, Henri-Jacques Delecluse, Stefan M. Willems, Melvin L. K. Chua, Pierre Busson, Kwok Wai Lo, Guido Wollmann, Nischalan Pillay, Bart Vanhaesebroeck, Valerie J. Lund
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nasopharyngeal carcinoma (NPC) lacks effective diagnostic and therapeutic strategies, in particular at advanced stages. Here, the authors show that expression of the somatostatin receptor 2 is induced by Epstein-Barr virus in NPC and has a key role i
Externí odkaz:
https://doaj.org/article/ff5d4bfec0f74e349a04c2a36d9baae8
Autor:
Jianguo Wang, Qiang Jiang, Oluwasijibomi Damola Faleti, Chi-Man Tsang, Min Zhao, Gongfa Wu, Sai-Wah Tsao, Minyi Fu, Yuxiang Chen, Tengteng Ding, Tuotuo Chong, Yufei Long, Xu Yang, Yuanbin Zhang, Yunxi Cai, Hanzhao Li, Manli Peng, Xiaoming Lyu, Xin Li
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 22, Iss , Pp 153-165 (2020)
Nasopharyngeal carcinoma (NPC) is an Epstein-Barr virus (EBV)-associated cancer characterized by a high degree of recurrence, angiogenesis, and metastasis. The importance of alternative pro-angiogenesis pathways including viral factors has emerged af
Externí odkaz:
https://doaj.org/article/2219685c8b1e4c45a0bc201d78d950fc
Autor:
Godfrey Chi-fung Chan, Xiwei Wang, Yanmei Zhang, Xiaofeng Mu, Chloe Ran Tu, Yuet Chung, Sai Wah Tsao, Wing-Hang Leung, Yu-lung Lau, Yinping Liu, Wenwei Tu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 2 (2022)
Background Radiotherapy is the first-line treatment for patients nasopharyngeal carcinoma (NPC), but its therapeutic efficacy is poor in some patients due to radioresistance. Adoptive T cell-based immunotherapy has also shown promise to control NPC;
Externí odkaz:
https://doaj.org/article/2e78c1e3c0504f5581549d4cd78713c9
Autor:
Nicholas Van Sciver, Makoto Ohashi, Dhananjay M. Nawandar, Nicholas P. Pauly, Denis Lee, Kathleen R. Makielski, Jillian A. Bristol, Sai Wah Tsao, Paul F. Lambert, Eric C. Johannsen, Shannon C. Kenney
Publikováno v:
PLoS Pathogens, Vol 17, Iss 11 (2021)
Epstein-Barr virus (EBV) is a human herpesvirus that causes infectious mononucleosis and contributes to both B-cell and epithelial-cell malignancies. EBV-infected epithelial cell tumors, including nasopharyngeal carcinoma (NPC), are largely composed
Externí odkaz:
https://doaj.org/article/cf1e2f37626547988264e0a8c5e31e20
Autor:
Jeff P. Bruce, Ka-Fai To, Vivian W. Y. Lui, Grace T. Y. Chung, Yuk-Yu Chan, Chi Man Tsang, Kevin Y. Yip, Brigette B. Y. Ma, John K. S. Woo, Edwin P. Hui, Michael K. F. Mak, Sau-Dan Lee, Chit Chow, Sharmila Velapasamy, Yvonne Y. Y. Or, Pui Kei Siu, Samah El Ghamrasni, Stephenie Prokopec, Man Wu, Johnny S. H. Kwan, Yuchen Liu, Jason Y. K. Chan, C. Andrew van Hasselt, Lawrence S. Young, Christopher W. Dawson, Ian C. Paterson, Lee-Fah Yap, Sai-Wah Tsao, Fei-Fei Liu, Anthony T. C. Chan, Trevor J. Pugh, Kwok-Wai Lo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/f4c5624de0d740c496d631d66856f4cf
Autor:
Shuai Zha, Ho‐Fai Chau, Wai Yin Chau, Lai Sheung Chan, Jun Lin, Kwok Wai Lo, William Chi‐Shing Cho, Yim Ling Yip, Sai Wah Tsao, Paul J. Farrell, Liang Feng, Jin Ming Di, Ga‐Lai Law, Hong Lok Lung, Ka‐Leung Wong
Publikováno v:
Advanced Science, Vol 8, Iss 5, Pp n/a-n/a (2021)
Abstract Using Epstein‐Barr virus (EBV)‐induced cancer cells and HeLa cells as a comparative study model, a novel and safe dual‐EBV‐oncoproteins‐targeting pH‐responsive peptide engineering, coating, and guiding approach to achieve precisi
Externí odkaz:
https://doaj.org/article/163854e960e4409ca34694a32d5c7cf9