Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sai Shyam Narayanan"'
Autor:
E K Radhakrishnan, Smitha V Bava, Sai Shyam Narayanan, Lekshmi R Nath, Arun Kumar T Thulasidasan, Eppurathu Vasudevan Soniya, Ruby John Anto
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104401 (2014)
We report mechanism-based evidence for the anticancer and chemopreventive efficacy of [6]-gingerol, the major active principle of the medicinal plant, Ginger (Zingiber officinale), in colon cancer cells. The compound was evaluated in two human colon
Externí odkaz:
https://doaj.org/article/126475e1abfa43b3b7014bc081fd6832
Rap1 and Cdc13 have complementary roles in preventing exonucleolytic degradation of telomere 5′ ends
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Scientific Reports
Scientific Reports
Telomere DNA ends with a single-stranded 3′ overhang. Long 3′ overhangs may cause aberrant DNA damage responses and accelerate telomere attrition, which is associated with cancer and aging, respectively. Genetic studies have indicated several imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0602e6c487ac647ac97ce978fb6c7206
https://doaj.org/article/ea94b149eb7b4623a8c3eeb2d766981c
https://doaj.org/article/ea94b149eb7b4623a8c3eeb2d766981c
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Telomeres, the DNA-protein structures capping the ends of linear chromosomes, are important for regulating replicative senescence and maintaining genome stability. Telomeres consist of G-rich repetitive sequences that end in a G-rich single-stranded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5482876ea7ef4d7ea21357ea6eea600a
http://europepmc.org/articles/PMC6915718
http://europepmc.org/articles/PMC6915718
Autor:
Dileep Kommula, M. S. R. Murty, Mohana Rao Katiki, Sai Shyam Narayanan, Ruby John Anto, B. Ramalingeswara Rao
Publikováno v:
Croatica Chemica Acta
Volume 92
Issue 3
Volume 92
Issue 3
The synthesis of a series of substituted hippuric acid (2-benzamidoacetic acid) derivatives containing arylsulfonylpiperazine nucleus (3a–j, 4a–j) is described. The compounds were synthesized by coupling hippuric/4-fluorohippuric acid with variou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::475aaa82dca53de03faab940efe6fd08
https://hrcak.srce.hr/226910
https://hrcak.srce.hr/226910
Publikováno v:
Molecular and Cellular Biochemistry. 365:191-202
Methionine aminopeptidase (MAP) performs the essential post-translational N-terminal methionine excision (NME) of nascent polypeptides during protein synthesis. To characterize MAP from Mycobacterium tuberculosis, two homolgues, mapA (Rv0734) and map
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7787d646c4ab61c888dfa619a9f7cb7e
https://doi.org/10.1007/s11010-012-1260-8
https://doi.org/10.1007/s11010-012-1260-8
Publikováno v:
FEMS Microbiology Letters. 320:40-47
Peptide deformylase (PDF) catalyses the removal of the N-formyl group from the nascent polypeptide during protein maturation. The PDF of Mycobacterium tuberculosis H37Rv (MtbPDF), overexpressed and purified from Escherichia coli, was characterized as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9abb7c3b1d4615b15a0352b23d7c496d
https://doi.org/10.1111/j.1574-6968.2011.02289.x
https://doi.org/10.1111/j.1574-6968.2011.02289.x
Autor:
Anil Kumar Patel, S.M. Das, Sai Shyam Narayanan, R. Rubex, Ashok Pandey, Kesavan Madhavan Nampoothiri, S. Krishna
Publikováno v:
Journal of Applied Microbiology. 105:59-67
Aim: Molecular cloning, overexpression and biochemical characterization of the genes from the Mycobacterium tuberculosis H37Rv genome having hypothetical β-lactamases activity. Methods and Results: Analysis of the M. tuberculosis H37Rv genome reveal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0780e4968152231bc5f142141c75f8c
https://doi.org/10.1111/j.1365-2672.2007.03721.x
https://doi.org/10.1111/j.1365-2672.2007.03721.x
Autor:
Kesavan Madhavan Nampoothiri, Sai Shyam Narayanan, Sumi J Menachery, Sita Ravikumar, Hemaraj Nandanwar, Sowmya P. Mohandas, Gayathri Suseelan
Publikováno v:
Applied biochemistry and biotechnology. 167(6)
The present study describes the exploitation of microbial biodiversity from Western Ghats of Kerala for screening of bioactives having β-lactamase inhibitory activities. A total of 700 pure cultures were isolated and were screened for antibacterial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::582935f13aca51fb836debed8faa8c08
https://pubmed.ncbi.nlm.nih.gov/22350938
https://pubmed.ncbi.nlm.nih.gov/22350938
Publikováno v:
Applied biochemistry and biotechnology. 151(2-3)
The methionine aminopeptidase (MetAP) catalyzes the removal of amino terminal methionine from newly synthesized polypeptide. MetAP from Mycobacterium smegmatis mc(2) 155 was purified from the culture lysate in four sequential steps to obtain a final
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::674b0167b4baa68eee7b830455da85eb
https://pubmed.ncbi.nlm.nih.gov/18594775
https://pubmed.ncbi.nlm.nih.gov/18594775
Autor:
Arun Kumar T. Thulasidasan, EK Radhakrishnan, Ruby John Anto, Lekshmi R Nath, Smitha V. Bava, Sai Shyam Narayanan, E. V. Soniya
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104401 (2014)
PLoS ONE
PLoS ONE
We report mechanism-based evidence for the anticancer and chemopreventive efficacy of [6]-gingerol, the major active principle of the medicinal plant, Ginger (Zingiber officinale), in colon cancer cells. The compound was evaluated in two human colon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c60b967072a537de67ade7802292f238
https://doi.org/10.1371/journal.pone.0104401
https://doi.org/10.1371/journal.pone.0104401