Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Sai Saroja Kolluru"'
Autor:
Felicia Reinitz, Elizabeth Y Chen, Benedetta Nicolis di Robilant, Bayarsaikhan Chuluun, Jane Antony, Robert C Jones, Neha Gubbi, Karen Lee, William Hai Dang Ho, Sai Saroja Kolluru, Dalong Qian, Maddalena Adorno, Katja Piltti, Aileen Anderson, Michelle Monje, H Craig Heller, Stephen R Quake, Michael F Clarke
Publikováno v:
eLife, Vol 11 (2022)
Alzheimer’s disease (AD) is a progressive neurodegenerative disease observed with aging that represents the most common form of dementia. To date, therapies targeting end-stage disease plaques, tangles, or inflammation have limited efficacy. Theref
Externí odkaz:
https://doaj.org/article/92c5abc287934048bbc8abb6eae7052f
Autor:
Ragini Phansalkar, Josephine Krieger, Mingming Zhao, Sai Saroja Kolluru, Robert C Jones, Stephen R Quake, Irving Weissman, Daniel Bernstein, Virginia D Winn, Gaetano D'Amato, Kristy Red-Horse
Publikováno v:
eLife, Vol 10 (2021)
Most cell fate trajectories during development follow a diverging, tree-like branching pattern, but the opposite can occur when distinct progenitors contribute to the same cell type. During this convergent differentiation, it is unknown if cells ‘r
Externí odkaz:
https://doaj.org/article/5b819ee9344840cb83dabc0bd4069398
Autor:
Colleen N McLaughlin, Maria Brbić, Qijing Xie, Tongchao Li, Felix Horns, Sai Saroja Kolluru, Justus M Kebschull, David Vacek, Anthony Xie, Jiefu Li, Robert C Jones, Jure Leskovec, Stephen R Quake, Liqun Luo, Hongjie Li
Publikováno v:
eLife, Vol 10 (2021)
Recognition of environmental cues is essential for the survival of all organisms. Transcriptional changes occur to enable the generation and function of the neural circuits underlying sensory perception. To gain insight into these changes, we generat
Externí odkaz:
https://doaj.org/article/74b6629249ee4630bde8783922a0e4bc
Autor:
Qijing Xie, Maria Brbic, Felix Horns, Sai Saroja Kolluru, Robert C Jones, Jiefu Li, Anay R Reddy, Anthony Xie, Sayeh Kohani, Zhuoran Li, Colleen N McLaughlin, Tongchao Li, Chuanyun Xu, David Vacek, David J Luginbuhl, Jure Leskovec, Stephen R Quake, Liqun Luo, Hongjie Li
Publikováno v:
eLife, Vol 10 (2021)
Neurons undergo substantial morphological and functional changes during development to form precise synaptic connections and acquire specific physiological properties. What are the underlying transcriptomic bases? Here, we obtained the single-cell tr
Externí odkaz:
https://doaj.org/article/52b08758320341fd9a60d8b91ca94a08
Autor:
Jing Ren, Alina Isakova, Drew Friedmann, Jiawei Zeng, Sophie M Grutzner, Albert Pun, Grace Q Zhao, Sai Saroja Kolluru, Ruiyu Wang, Rui Lin, Pengcheng Li, Anan Li, Jennifer L Raymond, Qingming Luo, Minmin Luo, Stephen R Quake, Liqun Luo
Publikováno v:
eLife, Vol 8 (2019)
Serotonin neurons of the dorsal and median raphe nuclei (DR, MR) collectively innervate the entire forebrain and midbrain, modulating diverse physiology and behavior. To gain a fundamental understanding of their molecular heterogeneity, we used plate
Externí odkaz:
https://doaj.org/article/eb730726e1314fd5a7371c54603afbe4
Autor:
Tzu-Chiao Lu, Maria Brbić, Ye-Jin Park, Tyler Jackson, Jiaye Chen, Sai Saroja Kolluru, Yanyan Qi, Nadja Sandra Katheder, Xiaoyu Tracy Cai, Seungjae Lee, Yen- Chung Chen, Niccole Auld, Chung-Yi Liang, Sophia H. Ding, Doug Welsch, Samuel D’Souza, Angela Oliveira Pisco, Robert C. Jones, Jure Leskovec, Eric C. Lai, Hugo J. Bellen, Liqun Luo, Heinrich Jasper, Stephen R. Quake, Hongjie Li
Aging is characterized by a decline in tissue function, but the underlying changes at cellular resolution across the organism remain unclear. Here, we present the Aging Fly Cell Atlas, a single-nucleus transcriptomic map of the whole agingDrosophila.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af71a9446b3c4735eeefa4f24a01855d
https://doi.org/10.1101/2022.12.06.519355
https://doi.org/10.1101/2022.12.06.519355
Autor:
Jun Xu, Yifang Liu, Hongjie Li, Alexander J. Tarashansky, Colin H. Kalicki, Ruei-Jiun Hung, Yanhui Hu, Aram Comjean, Sai Saroja Kolluru, Bo Wang, Stephen R. Quake, Liqun Luo, Andrew P. McMahon, Julian A. T. Dow, Norbert Perrimon
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Recent advances in single-cell sequencing provide a unique opportunity to gain novel insights into the diversity, lineage, and functions of cell types constituting a tissue/organ. Here, we performed a single-nucleus study of the adult Drosophila rena
Autor:
Benedetta Nicolis di Robilant, Elizabeth Y Chen, Felicia Reinitz, Bayarsaikhan Chuluun, Jane Antony, Robert C Jones, Neha Gubbi, Karen Lee, William Hai Dang Ho, Sai Saroja Kolluru, Dalong Qian, Maddalena Adorno, Katja Piltti, Aileen Anderson, Michelle Monje, H Craig Heller, Stephen R Quake, Michael F Clarke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c06b69fb3ac0c75f6f4029ed4b8b982
https://doi.org/10.7554/elife.66037.sa2
https://doi.org/10.7554/elife.66037.sa2
Autor:
Stephen F. Goodwin, Wouter Saelens, Zita Carvalho-Santos, Helen White-Cooper, K Rust, Norbert Perrimon, Cameron Wynn Berry, Brian Oliver, Stephen DiNardo, Carlos Ribeiro, Soumitra Pal, Hongjie Li, Julian A. T. Dow, Maria Brbic, Qijing Xie, Aaron M. Allen, K Brueckner, A Galenza, Quake S, Jure Leskovec, Frank Schnorrer, Todd G. Nystul, M. De Waegeneer, Margaret T. Fuller, Colleen N McLaughlin, Lucy Erin O'Brien, Stein Aerts, Sai Saroja Kolluru, Robert C. Jones, Kristofer Davie, Liqun Luo, Bart Deplancke, Sudhir Gopal Tattikota, Heinrich Jasper, Gardeux, Fabrice P. A. David, Teresa M. Przytycka, Janssens J, Erika Matunis, Jiwon Shim
The ability to obtain single cell transcriptomes for stable cell types and dynamic cell states is ushering in a new era for biology. We created the Tabula Drosophilae, a single cell atlas of the adult fruit fly which includes 580k cells from 15 indiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa87a3b68d07f8e95515861aa38827a5
https://hal.science/hal-03445082/document
https://hal.science/hal-03445082/document
Autor:
Ragini Phansalkar, Josephine Krieger, Mingming Zhao, Sai Saroja Kolluru, Robert C Jones, Stephen R Quake, Irving Weissman, Daniel Bernstein, Virginia D Winn, Gaetano D'Amato, Kristy Red-Horse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c27e322bce00696ef4379d3607a13d17
https://doi.org/10.7554/elife.70246.sa2
https://doi.org/10.7554/elife.70246.sa2