Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Sai Parng S Fung"'
Autor:
Sai Parng S Fung, Sofian M. Tijono, Jack U. Flanagan, Joanne F. Jamie, Brian D. Palmer, Lai-Ming Ching, Christopher J. Squire, Haiyan Wang, Petr Tomek, David J. A. Bridewell
Publikováno v:
Bioorganic & Medicinal Chemistry. 21:7595-7603
Screening of a fragment library identified 2-hydrazinobenzothiazole as a potent inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), an enzyme expressed by tumours that suppresses the immune system. Spectroscopic studies indicated that 2-hydrazinobenzo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2065a06b0acbc8f2edfeab7365d6c2e1
https://doi.org/10.1016/j.bmc.2013.10.037
https://doi.org/10.1016/j.bmc.2013.10.037
Autor:
Sai Parng S Fung, Joanne F. Jamie, Lai-Ming Ching, Brian D. Palmer, David J. A. Bridewell, Jack U. Flanagan, Petr Tomek
Publikováno v:
Analytical and Bioanalytical Chemistry. 405:2515-2524
Indoleamine 2,3-dioxygenase 1 (IDO1) is a tryptophan-catabolizing enzyme whose expression by a broad range of clinical tumors is associated with immunosuppression and poor patient outcome. Here we describe a new fluorescence assay for measuring IDO1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::983d51ca1cf00f1d185df18f117ea536
https://doi.org/10.1007/s00216-012-6650-y
https://doi.org/10.1007/s00216-012-6650-y