Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sai Harsha Krovi"'
Autor:
Scott B. Thompson, Eric J. Wigton, Sai Harsha Krovi, Jeffrey W. Chung, Robert A. Long, Jordan Jacobelli
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
Leukemias typically arise in the bone marrow and then spread to the blood and into other tissues. To disseminate into tissues, leukemia cells migrate into the blood stream and then exit the circulation by migrating across vascular endothelial barrier
Externí odkaz:
https://doaj.org/article/afc9c01cb6db49a2b593407fb3cd88a6
Autor:
Philippa Marrack, Sai Harsha Krovi, Daniel Silberman, Janice White, Eleanor Kushnir, Maki Nakayama, James Crooks, Thomas Danhorn, Sonia Leach, Randy Anselment, James Scott-Browne, Laurent Gapin, John Kappler
Publikováno v:
eLife, Vol 6 (2017)
Mature T cells bearing αβ T cell receptors react with foreign antigens bound to alleles of major histocompatibility complex proteins (MHC) that they were exposed to during their development in the thymus, a phenomenon known as positive selection. T
Externí odkaz:
https://doaj.org/article/79601c2f9b334c868bec5c43366ddd8c
Autor:
Sai Harsha Krovi, Vijay K. Kuchroo
Publikováno v:
Immunol Rev
Autoimmune diseases are characterized by dysfunctional immune systems that misrecognize self as non-self and cause tissue destruction. Several cell types have been implicated in triggering and sustaining disease. Due to a strong association of major
Autor:
Laurent Gapin, Mary Jessamine Michaels-Foster, Jingjing Zhang, Sai Harsha Krovi, Liyen Loh, James Scott-Browne, Tonya Brunetti
SummaryMost T lymphocytes leave the thymus as naïve cells with limited functionality. However, unique populations of T cells, commonly known as innate-like T cells, differentiate into functionally distinct effector subsets during thymic development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bf9c6b5ebabb54b1243f4a501d11371
https://doi.org/10.1101/2020.06.08.135129
https://doi.org/10.1101/2020.06.08.135129
Autor:
Laurent Gapin, Sai Harsha Krovi
Publikováno v:
European Journal of Immunology. 46:56-59
Conventional T cells have historically been linked to exacerbating allergy. By efficiently generating primarily TH 2 cells, allergens skew the immune response to produce IL-4, IL-13, and IgE. Previously, CD1a-responsive T cells were shown to function
Autor:
Brendan Kearney Reed, Frances Crawford, Ryan Hill, Niyun Jin, Sai Harsha Krovi, Janice White, Philippa Marrack, Kirk Hansen, John Kappler
Publikováno v:
The Journal of Immunology. 204:217.11-217.11
The identification of the peptide epitopes presented by major histocompatibility complex class II molecules (MHCII) that drive the CD4 T cell component of autoimmune diseases has presented a formidable challenge over several decades. In type-1 diabet
Autor:
Maki Nakayama, James P. Scott-Browne, Sai Harsha Krovi, Randy Anselment, Sonia M. Leach, James Crooks, Laurent Gapin, Eleanor Kushnir, John W. Kappler, Janice White, Thomas Danhorn, Philippa Marrack, Daniel Silberman
Publikováno v:
eLife, Vol 6 (2017)
eLife
eLife
Mature T cells bearing αβ T cell receptors react with foreign antigens bound to alleles of major histocompatibility complex proteins (MHC) that they were exposed to during their development in the thymus, a phenomenon known as positive selection. T
Autor:
Maki Nakayama, Janice White, James P. Scott-Browne, Daniel Silberman, James L. Crooks, Sai Harsha Krovi, Thomas Danhorn, Laurent Gapin, Sonia M. Leach, Philippa Marrack, Eleanor Kushnir, Randy Anselment, John W. Kappler
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a45b0e940f937232dc8977f58d5083af
https://doi.org/10.7554/elife.30918.028
https://doi.org/10.7554/elife.30918.028
Autor:
Eleanor Kushnir, Maki Nakayama, James P. Scott-Browne, Daniel Silberman, Randy Anselment, Laurent Gapin, John W. Kappler, James Crooks, Janice White, Sonia M. Leach, Thomas Danhorn, Philippa Marrack, Sai Harsha Krovi
Mature T cells bearing αβ T cell receptors react with foreign antigens bound to alleles of major histocompatibility complex proteins (MHC) that they were exposed to during their development in the thymus, a phenomenon known as positive selection. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6eeade98ff772f4c6fdad8c482bf869
https://doi.org/10.1101/176388
https://doi.org/10.1101/176388
Autor:
Laurent Gapin, Janice White, Philippa Marrack, Jennifer L. Matsuda, Sai Harsha Krovi, Kathryn D. Tuttle, James J. Gross, James L. Crooks, John W. Kappler, Daniel Silberman, Richard Reisdorph
The interaction of αβ T-cell antigen receptors (TCRs) with peptides bound to MHC molecules lies at the center of adaptive immunity. Whether TCRs have evolved to react with MHC or, instead, processes in the thymus involving coreceptors and other mol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039657ecdaa77e92cb3e2cce4040ba00
https://europepmc.org/articles/PMC5035841/
https://europepmc.org/articles/PMC5035841/