Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sai Chaitanya Chiliveri"'
Autor:
Seung Bum Park, Mohsin Khan, Sai Chaitanya Chiliveri, Xin Hu, Parker Irvin, Madeleine Leek, Ailis Grieshaber, Zongyi Hu, Eun Sun Jang, Ad Bax, T. Jake Liang
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract Since the emergence of the Omicron variants at the end of 2021, they quickly became the dominant variants globally. The Omicron variants may be more easily transmitted compared to the earlier Wuhan and the other variants. In this study, we a
Externí odkaz:
https://doaj.org/article/91540e85d7364d0480d15dc87697cdce
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-9 (2022)
The binding of a drug targeting the active site of a predominantly monomeric SARS-CoV-2 main protease (MProM) favors an equilibrium shift to MProM dimer formation with two equivalent active sites. These results suggest targeting the monomeric active
Externí odkaz:
https://doaj.org/article/613c4d7153af4acfb58e7dadb2dc7ff4
Publikováno v:
Chemical Reviews. 122:9307-9330
The measurement and application of residual dipolar couplings (RDCs) in solution NMR studies of biological macromolecules has become well established over the past quarter of a century. Numerous methods for generating the requisite anisotropic orient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7c5e9dce7bc2cde8bd2579c221169c8
https://doi.org/10.1021/acs.chemrev.1c00730
https://doi.org/10.1021/acs.chemrev.1c00730
Interaction of the bacterial division regulator MinE with lipid bicelles studied by NMR spectroscopy
Autor:
Mengli Cai, Vitali Tugarinov, Sai Chaitanya Chiliveri, Ying Huang, Charles D. Schwieters, Kyoshi Mizuuchi, G. Marius Clore
Publikováno v:
Journal of Biological Chemistry. 299:103037
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5139b5d488d3f545419150a21245618
https://doi.org/10.1016/j.jbc.2023.103037
https://doi.org/10.1016/j.jbc.2023.103037
Publikováno v:
Journal of molecular biology. 434(16)
The envelope glycoprotein gp41 of the HIV-1 virus mediates its entry into the host cell. During this process, gp41 undergoes large conformational changes and the energy released in the remodeling events is utilized to overcome the barrier associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4422d56b44aecfbe8d2f9e35acfe1b88
https://pubmed.ncbi.nlm.nih.gov/35700771
https://pubmed.ncbi.nlm.nih.gov/35700771
Publikováno v:
Angew Chem Int Ed Engl
The membrane proximal external region (MPER) of HIV-1 gp41 contains epitopes for at least four broadly neutralizing antibodies. Depending on solution conditions and construct design, different structures have been reported for this segment. We show t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eef65133ef23ccfcf7f631edf2fef6a7
https://doi.org/10.1002/anie.202008804
https://doi.org/10.1002/anie.202008804
Publikováno v:
Science Advances
Description
Heptad repeat regions of SARS-CoV-2 spike protein transiently disrupt membrane integrity while driving cellular entry.
Entry of SARS-CoV-2 into a host cell is mediated by spike, a class I viral fusion protein responsible for mer
Heptad repeat regions of SARS-CoV-2 spike protein transiently disrupt membrane integrity while driving cellular entry.
Entry of SARS-CoV-2 into a host cell is mediated by spike, a class I viral fusion protein responsible for mer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee00f1718afd24eea2265d0dde84e2f
https://doi.org/10.1126/sciadv.abk2226
https://doi.org/10.1126/sciadv.abk2226
Publikováno v:
Chemphyschem
Double electron-electron resonance (DEER) EPR spectroscopy is a powerful method for obtaining distance distributions between pairs of engineered nitroxide spin-labels in proteins and other biological macromolecules. These measurements require the use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f8623c6ec5e497cf5858d50129f51f8
https://europepmc.org/articles/PMC8179457/
https://europepmc.org/articles/PMC8179457/
Publikováno v:
Journal of the American Chemical Society. 140:34-37
Cryo-electron microscopy and X-ray crystallography have shown that the pre- and post-fusion states of the HIV-1 gp41 viral coat protein, although very different from one another, each adopt C3 symmetric structures. A stable homotrimeric structure for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24529f4709106aa7f15a031a3802cccf
https://doi.org/10.1021/jacs.7b10245
https://doi.org/10.1021/jacs.7b10245
Publikováno v:
Biomolecular NMR Assignments. 9:253-256
RNA interference (RNAi) is a conserved biological response to dsRNA and regulates the expression of protein-coding genes to mediate resistance to both endogenous parasitic and exogenous pathogenic nucleic acids. In RNAi pathway, dsRNA binding protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5994b6e28ee36f39a539398a70d22a86
https://doi.org/10.1007/s12104-014-9585-8
https://doi.org/10.1007/s12104-014-9585-8