Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Sahithi J, Kuravi"'
Autor:
Sahithi J. Kuravi, Niaz S. Ahmed, Kirk A. Taylor, Emily M. Capes, Alex Bye, Amanda J. Unsworth, Jonathan M. Gibbins, Nicholas Pugh
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11689 (2023)
Zinc (Zn2+) is released by platelets during a hemostatic response to injury. Extracellular zinc ([Zn2+]o) initiates platelet activation following influx into the platelet cytosol. However, the mechanisms that permit Zn2+ influx are unknown. Fluctuati
Externí odkaz:
https://doaj.org/article/d04651147f4546c5b5a1b43159500bfc
Autor:
Myriam Chimen, Aigli Evryviadou, Clare L. Box, Matthew J. Harrison, Jon Hazeldine, Lea H. Dib, Sahithi J. Kuravi, Holly Payne, Joshua M.J. Price, Dean Kavanagh, Asif J. Iqbal, Sian Lax, Neena Kalia, Alex Brill, Steve G. Thomas, Antonio Belli, Nicholas Crombie, Rachel A. Adams, Shelley-Ann Evans, Hans Deckmyn, Janet M. Lord, Paul Harrison, Steve P. Watson, Gerard B. Nash, G. Ed Rainger
Publikováno v:
Haematologica, Vol 105, Iss 5 (2020)
Interactions between platelets, leukocytes and the vessel wall provide alternative pathological routes of thrombo-inflammatory leukocyte recruitment. We found that when platelets were activated by a range of agonists in whole blood, they shed platele
Externí odkaz:
https://doaj.org/article/148d3754311e4a4b82c8c3464dde2293
Autor:
Sahithi J Kuravi, Clara M Yates, Mark Foster, Paul Harrison, Jon Hazeldine, Peter Hampson, Chris Watson, Antonio Belli, Mark Midwinter, Gerard B Nash
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183640 (2017)
Extracellular vesicles (EV) released into the circulation after traumatic injury may influence complications. We thus evaluated the numbers of EV in plasma over 28 days after trauma and evaluated their pro-coagulant and inflammatory effects.37 patien
Externí odkaz:
https://doaj.org/article/6e7b03f6bf084ca5a97dbaf897cf9b7d
Autor:
Alexander Brill, Neena Kalia, Sahithi J. Kuravi, Gerard B. Nash, Janet M. Lord, G. Ed Rainger, Dean Kavanagh, Hans Deckmyn, Clare L. Box, Rachel A. Adams, Sian Lax, Nicholas Crombie, Lea H. Dib, Holly Payne, Steven G. Thomas, Asif J. Iqbal, Shelley-Ann Evans, Joshua Price, Steve P. Watson, Antonio Belli, Jon Hazeldine, Aigli Evryviadou, Paul Harrison, Myriam Chimen, Matthew J. Harrison
Publikováno v:
Haematologica
Interactions between platelets, leukocytes and the vessel wall provide alternative pathological routes of thrombo-inflammatory leukocyte recruitment. We found that when platelets were activated by a range of agonists in whole blood, they shed platele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf64b69323ee0f6da7da570d4ceb48bc
https://lirias.kuleuven.be/handle/123456789/654884
https://lirias.kuleuven.be/handle/123456789/654884
Publikováno v:
Inflammation
We tested the ability of platelet-derived extracellular vesicles (PEV) to promote adhesion of flowing neutrophils to endothelial cells (EC). PEV were collected from platelets stimulated with collagen-related peptide, and differential centrifugation w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3844c0c5db280ae86f6a4564cd9520a
https://doi.org/10.1007/s10753-018-0893-5
https://doi.org/10.1007/s10753-018-0893-5
Autor:
G. Ed Rainger, Andrew W. Bradbury, Rajiv K. Vohra, Gerard B. Nash, James Hodson, Mehtab Ahmad, Sahithi J. Kuravi
Publikováno v:
European Journal of Vascular and Endovascular Surgery. 56:130-135
OBJECTIVE/BACKGROUND In a pilot study, a relationship between abdominal aortic aneurysm (AAA) diameter and serum interleukin (IL)-1α levels was reported, and that endothelial cell (EC) activation in vitro in response to serum from patients with AAA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24e291ccb727a531eda10baba494fa52
https://doi.org/10.1016/j.ejvs.2018.01.015
https://doi.org/10.1016/j.ejvs.2018.01.015
Autor:
Mark J. Midwinter, Chris Watson, Peter Hampson, Sahithi J. Kuravi, Paul Harrison, Gerard B. Nash, Antonio Belli, Mark A. Foster, Jon Hazeldine, Clara M. Yates
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 8, p e0183640 (2017)
PLoS ONE, Vol 12, Iss 8, p e0183640 (2017)
Background Extracellular vesicles (EV) released into the circulation after traumatic injury may influence complications. We thus evaluated the numbers of EV in plasma over 28 days after trauma and evaluated their pro-coagulant and inflammatory effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74939c4ed7221b334549aeab8183230e
http://europepmc.org/articles/PMC5570308
http://europepmc.org/articles/PMC5570308
Autor:
Sahithi J. Kuravi, Mohammed Alassiri, Francesca Barone, Saba Nayar, Joseph Robinson, Christopher D. Buckley, Parth Narendran, Helen M. McGettrick, Lucy S. K. Walker, David A. Copland, Jessica Hitchcock, Karim Raza, Bonita H. R. Apta, Arjun Odedra, Andrew Filer, Amy Kennedy, Clara M. Yates, Andrew D. Dick, Myriam Chimen, Ashley Martin, Gerard B. Nash, G. Ed Rainger, Neena Kalia, Matthew J. Harrison, Adam F. Cunningham
Publikováno v:
Nature medicine. 21(5)
During an inflammatory response, lymphocyte recruitment into tissue must be tightly controlled because dysregulated trafficking contributes to the pathogenesis of chronic disease. Here we show that during inflammation and in response to adiponectin,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e0ec178fc23015ca848e0eab291eeb8
https://pubmed.ncbi.nlm.nih.gov/26367028
https://pubmed.ncbi.nlm.nih.gov/26367028
Autor:
Sahithi J, Kuravi, Helen M, McGettrick, Simon C, Satchell, Moin A, Saleem, Lorraine, Harper, Julie M, Williams, George Ed, Rainger, Caroline O S, Savage
Publikováno v:
The Journal of Immunology Author Choice
Stromal cells actively modulate the inflammatory process, in part by influencing the ability of neighboring endothelial cells to support the recruitment of circulating leukocytes. We hypothesized that podocytes influence the ability of glomerular end
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7853ec017d1ce76df0d2a00dfcb9ef5d
https://pubmed.ncbi.nlm.nih.gov/24872191
https://pubmed.ncbi.nlm.nih.gov/24872191
Autor:
Julie M. Williams, G. Ed Rainger, Lorraine Harper, Simon C. Satchell, Caroline O. S. Savage, Samantha Tull, Anne Bevins, Sahithi J. Kuravi
Publikováno v:
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 27(12)
Background. Neutrophil recruitment into glomerular tissues and reduced capillary wall integrity has been implicated in the development of vasculitic glomerulonephritis (VGN). This study investigated the stages and mechanisms through which neutrophil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b33514ca53d91b04a25f915755e3fee6
https://pubmed.ncbi.nlm.nih.gov/22785107
https://pubmed.ncbi.nlm.nih.gov/22785107