Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sahil Pontula"'
Publikováno v:
Chemical Reviews. 121:13797-13868
Researchers have worked for many decades to master the rules of biomolecular design that would allow artificial biopolymer complexes to self-assemble and function similarly to the diverse biochemical constructs displayed in natural biological systems
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::899c63130f42834ee027aed636304ab4
https://doi.org/10.1021/acs.chemrev.0c01332
https://doi.org/10.1021/acs.chemrev.0c01332
Although micro-lensing of macro-lensed quasars and supernovae provides unique opportunities for several kinds of investigations, it can add unwanted and sometimes substantial noise. While micro-lensing flux anomalies may be safely ignored for some ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::273a9513681702698ac6a9c6edc09e0a
Autor:
Jørgen Kjems, Kristen Froehlich, Emily Mihalko, Ashley C. Brown, Abhichart Krissanaprasit, Ebbe Sloth Andersen, Daniel M. Dupont, Thomas H. LaBean, Carson M Key, Sahil Pontula
Anticoagulants are commonly utilized during surgeries and to treat thrombotic diseases like stroke and deep vein thrombosis. However, conventional anticoagulants have serious side-effects, narrow therapeutic windows, and lack safe reversal agents (an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1052d64db368d624bf22005cf5ed6da
https://doi.org/10.1101/2020.09.29.319590
https://doi.org/10.1101/2020.09.29.319590
Autor:
Carson M Key, Sahil Pontula, Matthew Hart, Ebbe Sloth Andersen, Abhichart Krissanaprasit, Pedro Carriel, Michael Fergione, Thomas H. LaBean, Jørgen Kjems, Kristen Froehlich
Publikováno v:
Advanced Materials
Krissanaprasit, A, Key, C, Fergione, M, Froehlich, K, Pontula, S, Hart, M, Carriel, P, Kjems, J, Andersen, E S & LaBean, T H 2019, ' Genetically Encoded, Functional Single-Strand RNA Origami : Anticoagulant ', Advanced Materials, vol. 31, no. 21, 1808262 . https://doi.org/10.1002/adma.201808262
Krissanaprasit, A, Key, C, Fergione, M, Froehlich, K, Pontula, S, Hart, M, Carriel, P, Kjems, J, Andersen, E S & LaBean, T H 2019, ' Genetically Encoded, Functional Single-Strand RNA Origami : Anticoagulant ', Advanced Materials, vol. 31, no. 21, 1808262 . https://doi.org/10.1002/adma.201808262
Nucleic acid aptamers selected for thrombin binding have been previously shown to possess anticoagulant activity; however, problems with rapid renal clearance and short circulation half-life have prevented translation to clinical usefulness. Here, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c7611fcf72eda2e0524412d8a8f9af7
Autor:
Abhichart Krissanaprasit, Daniel M. Dupont, Carson M Key, Emily Mihalko, Sahil Pontula, Ebbe Sloth Andersen, Kristen Froehlich, Ashley C. Brown, Jørgen Kjems, Thomas H. LaBean
Publikováno v:
Advanced Healthcare Materials
Krissanaprasit, A, Key, C M, Froehlich, K, Pontula, S, Mihalko, E, Dupont, D M, Andersen, E S, Kjems, J, Brown, A C & LaBean, T H 2021, ' Multivalent Aptamer-Functionalized Single-Strand RNA Origami as Effective, Target-Specific Anticoagulants with Corresponding Reversal Agents ', Advanced Healthcare Materials, vol. 10, no. 11, 2001826 . https://doi.org/10.1002/adhm.202001826
Krissanaprasit, A, Key, C M, Froehlich, K, Pontula, S, Mihalko, E, Dupont, D M, Andersen, E S, Kjems, J, Brown, A C & LaBean, T H 2021, ' Multivalent Aptamer-Functionalized Single-Strand RNA Origami as Effective, Target-Specific Anticoagulants with Corresponding Reversal Agents ', Advanced Healthcare Materials, vol. 10, no. 11, 2001826 . https://doi.org/10.1002/adhm.202001826
Anticoagulants are commonly utilized during surgeries and to treat thrombotic diseases like stroke and deep vein thrombosis. However, conventional anticoagulants have serious side-effects, narrow therapeutic windows, and lack safe reversal agents (an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2ad2e4a2c6026eaeac84b1605a61699
https://doi.org/10.1002/adhm.202001826
https://doi.org/10.1002/adhm.202001826