Zobrazeno 1 - 10
of 463
pro vyhledávání: '"Sahil Khanna"'
Publikováno v:
Mayo Clinic Proceedings: Digital Health, Vol 2, Iss 2, Pp 177-180 (2024)
Navigating clinical guidelines can be complex for real-time health care decision making. Our study evaluates the chat generative prerained transformer (ChatGPT)-4 in improving responses to clinical questions by integrating guidelines on Clostridioide
Externí odkaz:
https://doaj.org/article/583d1db6c7c84fc2ae34fbc3101b7904
Publikováno v:
Intestinal Research, Vol 22, Iss 2, Pp 208-212 (2024)
Externí odkaz:
https://doaj.org/article/e2dc122e7ac247ba8515edd569162e1e
Autor:
Vinod K. Gupta, Sanu Rajendraprasad, Mahmut Ozkan, Dhanya Ramachandran, Sumera Ahmad, Johan S. Bakken, Krzysztof Laudanski, Ognjen Gajic, Brent Bauer, Simon Zec, David W. Freeman, Sahil Khanna, Aditya Shah, Joseph H. Skalski, Jaeyun Sung, Lioudmila V. Karnatovskaia
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Dysbiosis of the gut microbiome is frequent in the intensive care unit (ICU), potentially leading to a heightened risk of nosocomial infections. Enhancing the gut microbiome has been proposed as a strategic approach to mitigate po
Externí odkaz:
https://doaj.org/article/8c1c549ea8624bdc9410f8084507b0a0
Autor:
Paul Feuerstadt, Jessica R. Allegretti, Erik R. Dubberke, Amy Guo, Adam Harvey, Min Yang, Viviana Garcia-Horton, Mirko Fillbrunn, Glenn Tillotson, Lindy L. Bancke, Kerry LaPlante, Kevin W. Garey, Sahil Khanna
Publikováno v:
Infectious Diseases and Therapy, Vol 13, Iss 1, Pp 221-236 (2024)
Abstract Introduction Clostridioides difficile infection (CDI) causes symptoms of varying severity and negatively impacts patients’ health-related quality of life (HRQL). Despite antibiotic treatment, recurrence of CDI (rCDI) is common and imposes
Externí odkaz:
https://doaj.org/article/60bcb17d6e844671925f5267b451bedd
Publikováno v:
Infectious Diseases and Therapy, Vol 12, Iss 2, Pp 703-709 (2022)
Abstract Introduction Effective treatments for recurrent Clostridioides difficile infection (rCDI) are urgently needed. RBX2660 is an investigational microbiota-based live biotherapeutic to reduce CDI recurrence following standard-of-care antibiotic
Externí odkaz:
https://doaj.org/article/2e7f50ec5e7e4df399a1afc1eec29479
Autor:
Christine Lee, Thomas Louie, Lindy Bancke, Beth Guthmueller, Adam Harvey, Paul Feuerstadt, Sahil Khanna, Robert Orenstein, Erik R. Dubberke
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 16 (2023)
Background: Microbiota-based treatments reduce the incidence of recurrent Clostridioides difficile infections (rCDIs), but prospectively collected safety data needed to broaden patient access and protect public health have been limited. Objectives: W
Externí odkaz:
https://doaj.org/article/8cc4ae3fc160414a878b1f6287d6adf4
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 16 (2023)
Background: Microbiota restoration is highly effective to treat recurrent Clostridioides difficile infection (CDI) in observational studies (cure rates >90%) but efficacy in controlled clinical trials appears to be lower. Objectives: To perform an up
Externí odkaz:
https://doaj.org/article/4a8aae0eaa284b70b1af3fe70a47ac5a
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 16 (2023)
Background: The incidence of Clostridioides difficile infection (CDI) in peripartum women is rising, but limited data on its effect on maternal and neonatal outcomes are available. Objective: To study the effect of peripartum CDI on pregnancy and neo
Externí odkaz:
https://doaj.org/article/d28184f361a14da9b1d099f5f46052ae
Autor:
Kanika Sehgal, June Tome, Amrit K. Kamboj, Ross A. Dierkhising, Darrell S. Pardi, Sahil Khanna
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 16 (2023)
Background: Microscopic colitis (MC) causes chronic diarrhea. It has two histologic subtypes: lymphocytic colitis (LC) and collagenous colitis (CC). Little is known about the natural progression of disease with time and with treatment. Objectives: We
Externí odkaz:
https://doaj.org/article/96645113766c40979fbbd084a9020eaa
Autor:
Robert Orenstein, Erik R. Dubberke, Sahil Khanna, Christine H. Lee, David Yoho, Stuart Johnson, Gail Hecht, Herbert L. DuPont, Dale N. Gerding, Ken F. Blount, Sarah Mische, Adam Harvey
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background Effective treatment options for recurrent Clostridioides difficile infection (rCDI) are limited, with high recurrence rates associated with the current standard of care. Herein we report results from an open-label Phase 2 trial to
Externí odkaz:
https://doaj.org/article/2b6ddb482f4647ea80752eeb69327c09