Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sahil Chandhok"'
Autor:
Dane Marijan, Evgenia A. Momchilova, Daniel Burns, Sahil Chandhok, Richard Zapf, Holger Wille, Davit A. Potoyan, Timothy E. Audas
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract To survive, cells must respond to changing environmental conditions. One way that eukaryotic cells react to harsh stimuli is by forming physiological, RNA-seeded subnuclear condensates, termed amyloid bodies (A-bodies). The molecular constit
Externí odkaz:
https://doaj.org/article/54c347ea78224ba19f53776fd365c006
Autor:
Sahil Chandhok, Lionel Pereira, Evgenia A. Momchilova, Dane Marijan, Richard Zapf, Emma Lacroix, Avneet Kaur, Shayan Keymanesh, Charles Krieger, Timothy E. Audas
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The formation of protein aggregates is a hallmark of many neurodegenerative diseases and systemic amyloidoses. These disorders are associated with the fibrillation of a variety of proteins/peptides, which ultimately leads to cell toxicity an
Externí odkaz:
https://doaj.org/article/b97ace8c3fae406b87b7291192604c1f
Autor:
Stephanie Vlachos, Byoungjoo Yoo, Ryan D. Morin, Lionel Pereira, Krysta M. Coyle, Richard Zapf, Timothy E. Audas, Nicholas Harden, Emma Lacroix, Sahil Chandhok, Dane Marijan
Publikováno v:
Journal of Cell Science. 134
In response to environmental stress, human cells have been shown to form reversible amyloid aggregates within the nucleus, termed amyloid bodies (A-bodies). These protective physiological structures share many of the biophysical characteristics assoc
Autor:
Monica Luo, Ronnie Tse, Dane Marijan, Sahil Chandhok, Emma Lacroix, Timothy E. Audas, Keenan Elliott
Publikováno v:
FEBS Letters. 593:3162-3172
Physiological amyloid aggregation occurs within the nuclei of stress-treated cells. These structures, termed Amyloid bodies (A-bodies), assemble through the rapid accumulation of proteins into dense membrane-less organelles, which possess the same bi