Novel hybrids of thiazolidinedione-1,3,4-oxadiazole derivatives: synthesis, molecular docking, MD simulations, ADMET study, in vitro , and in vivo anti-diabetic assessment.

Autor: Srinivasa MG; Department of Pharmaceutical Chemistry, NGSM Institute of Pharmaceutical Sciences (NGSMIPS), Nitte (Deemed to Be University) Mangalore-575018 Karnataka India revan@nitte.edu.in., Paithankar JG; Division of Environmental Health and Toxicology, Nitte University Centre for Science Education and Research (NUCSER), Nitte (Deemed to Be University) Mangalore-575018 Karnataka India., Saheb Birangal SR; Department of Pharmaceutical Chemistry, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education (MAHE) Manipal-5761042 Karnataka India., Pai A; Department of Pharmaceutical Chemistry, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education (MAHE) Manipal-5761042 Karnataka India., Pai V; Department of Pharmacognosy, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education (MAHE) Manipal-5761042 Karnataka India., Deshpande SN; Department of Pharmaceutical Chemistry, NGSM Institute of Pharmaceutical Sciences (NGSMIPS), Nitte (Deemed to Be University) Mangalore-575018 Karnataka India revan@nitte.edu.in., Revanasiddappa BC; Department of Pharmaceutical Chemistry, NGSM Institute of Pharmaceutical Sciences (NGSMIPS), Nitte (Deemed to Be University) Mangalore-575018 Karnataka India revan@nitte.edu.in.

Publikováno v: RSC advances [RSC Adv] 2023 Jan 09; Vol. 13 (3), pp. 1567-1579. Date of Electronic Publication: 2023 Jan 09 (Print Publication: 2023).