Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Saharinen Juha"'
Autor:
Saharinen Juha, Knuutila Sakari, Hollmén Jaakko, Sarhadi Virinder K, Puustinen Anne, Hienonen-Kempas Tuija, Ruosaari Salla, Wikman Harriet, Anttila Sisko
Publikováno v:
BMC Medical Genomics, Vol 1, Iss 1, p 55 (2008)
Abstract Background Studies on asbestos-induced tumourigenesis have indicated the role of, e.g., reactive oxygen/nitrogen species, mitochondria, as well as NF-κB and MAPK signalling pathways. The exact molecular mechanisms contributing to asbestos-m
Externí odkaz:
https://doaj.org/article/88364fffdaf84d8ab12f516bef09e9d4
Autor:
Gentile Massimiliano, Cooper Jonathan D, Kopra Outi, Saharinen Juha, von Schantz Carina, Hovatta Iiris, Peltonen Leena, Jalanko Anu
Publikováno v:
BMC Genomics, Vol 9, Iss 1, p 146 (2008)
Abstract Background The neuronal ceroid lipofuscinoses (NCL) are a group of children's inherited neurodegenerative disorders, characterized by blindness, early dementia and pronounced cortical atrophy. The similar pathological and clinical profiles o
Externí odkaz:
https://doaj.org/article/f198ca15b2e44459b98b20936cd0e94f
Autor:
Alhopuro, Pia, Phichith, Denis, Tuupanen, Sari, Sammalkorpi, Heli, Nybondas, Miranda, Saharinen, Juha, Robinson, James P., Yang, Zhaohui, Chen, Li-Qiong, Orntoft, Torben, Mecklin, Jukka-Pekka, Järvinen, Heikki, Eng, Charis, Moeslein, Gabriela, Shibata, Darryl, Houlston, Richard S., Lucassen, Anneke, Tomlinson, Ian P. M., Launonen, Virpi, Ristimäki, Ari, Arango, Diego, Karhu, Auli, Sweeney, H. Lee, Aaltonen, Lauri A.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2008 Apr 01. 105(14), 5513-5518.
Externí odkaz:
https://www.jstor.org/stable/25461635
Autor:
Petrova, Tatiana V., Nykänen, Antti, Norrmén, Camilla, Ivanov, Konstantin I., Andersson, Leif C., Haglund, Caj, Puolakkainen, Pauli, Wempe, Frank, von Melchner, Harald, Gradwohl, Gérard, Vanharanta, Sakari, Aaltonen, Lauri A., Saharinen, Juha, Gentile, Massimiliano, Clarke, Alan, Taipale, Jussi, Oliver, Guillermo, Alitalo, Kari
Publikováno v:
In Cancer Cell 6 May 2008 13(5):407-419
Autor:
Ilmarinen, Tanja, Kangas, Hannele, Kytömaa, Taina, Eskelin, Petra, Saharinen, Juha, Seeler, Jacob-S., Tanhuanpää, Kimmo, Chan, Fiona Yih-Ling, Slattery, Robyn Maree, Alakurtti, Kirsi, Palvimo, Jorma J., Ulmanen, Ismo
Publikováno v:
In Molecular Immunology 2008 45(7):1847-1862
Autor:
von Schantz, Carina1 carina.von.schantz@ktl.fi, Saharinen, Juha1,2 juha.saharinen@ktl.fi, Kopra, Outi1,3,4 outi.kopra@helsinki.fi, Cooper, Jonathan D.5 j.cooper@iop.kcl.ac.uk, Gentile, Massimiliano2 massimiliano.gentile@helsinki.fi, Hovatta, Iiris1,6 iiris.hovatta@ktl.fi, Peltonen, Leena1,7,8 leena.peltonen@ktl.fi, Jalanko, Anu1 anu.jalanko@ktl.fi
Publikováno v:
BMC Genomics. 2008, Vol. 9, Special section p1-14. 14p. 1 Color Photograph, 2 Diagrams, 2 Charts, 1 Graph.
Publikováno v:
In Journal of Biological Chemistry 12 November 1999 274(46):32619-32630
Autor:
Aulchenko, Yurii S, Ripatti, Samuli, Lindqvist, Ida, Boomsma, Dorret, Heid, Iris M, Pramstaller, Peter P, Penninx, Brenda W J H, Janssens, A Cecile J W, Wilson, James F, Spector, Tim, Martin, Nicholas G, Pedersen, Nancy L, Kyvik, Kirsten Ohm, Kaprio, Jaakko, Hofman, Albert, Freimer, Nelson B, Jarvelin, Marjo-Riitta, Gyllensten, Ulf, Campbell, Harry, Rudan, Igor, Johansson, Asa, Marroni, Fabio, Hayward, Caroline, Vitart, Veronique, Jonasson, Inger, Pattaro, Cristian, Wright, Alan, Hastie, Nick, Pichler, Irene, Hicks, Andrew A, Falchi, Mario, Willemsen, Gonneke, Hottenga, Jouke-Jan, de Geus, Eco J C, Montgomery, Grant W, Whitfield, John, Magnusson, Patrik, Saharinen, Juha, Perola, Markus, Silander, Kaisa, Isaacs, Aaron, Sijbrands, Eric J G, Uitterlinden, Andre G, Witteman, Jacqueline C M, Oostra, Ben A, Elliott, Paul, Ruokonen, Aimo, Sabatti, Chiara, Gieger, Christian, Meitinger, Thomas, Kronenberg, Florian, Döring, Angela, Wichmann, H-Erich, Smit, Johannes H, McCarthy, Mark I, van Duijn, Cornelia M, Peltonen, Leena, Consortium, ENGAGE
Publikováno v:
Nature Genetics; Vol 41
Nature Genetics, 41(1), 47-55. Nature Publishing Group
Aulchenko, Y S, Ripatti, S, Lindqvist, I, Boomsma, D, Heid, I M, Pramstaller, P P, Penninx, B W J H, Janssens, A C J W, Wilson, J F, Spector, T, Martin, N G, Pedersen, N L, Kyvik, K O, Kaprio, J, Hofman, A, Freimer, N B, Jarvelin, M-R, Gyllensten, U, Campbell, H, Rudan, I, Johansson, A, Marroni, F, Hayward, C, Vitart, V, Jonasson, I, Pattaro, C, Wright, A, Hastie, N, Pichler, I, Hicks, A A, Falchi, M, Willemsen, G, Hottenga, J-J, de Geus, E J C, Montgomery, G W, Whitfield, J, Magnusson, P, Saharinen, J, Perola, M, Silander, K, Isaacs, A, Sijbrands, E J G, Uitterlinden, A G, Witteman, J C M, Oostra, B A, Elliott, P, Ruokonen, A, Sabatti, C & Gieger, C & Meitinger, T 2009, ' Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts ', Nature Genetics, vol. 41, no. 1, pp. 47-55 . https://doi.org/10.1038/ng.269
Aulchenko, Y S, Ripatti, S, Lindqvist, I, Boomsma, D, Heid, I M, Pramstaller, P P, Penninx, B W J H, Janssens, A C J W, Wilson, J F, Spector, T, Martin, N G, Pedersen, N L, Kyvik, K O, Kaprio, J, Hofman, A, Freimer, N B, Jarvelin, M-R, Gyllensten, U, Campbell, H, Rudan, I, Johansson, A, Marroni, F, Hayward, C, Vitart, V, Jonasson, I, Pattaro, C, Wright, A, Hastie, N, Pichler, I, Hicks, A A, Falchi, M, Willemsen, G, Hottenga, J-J, de Geus, E J C, Montgomery, G W, Whitfield, J, Magnusson, P, Saharinen, J, Perola, M, Silander, K, Isaacs, A, Sijbrands, E J G, Uitterlinden, A G, Witteman, J C M, Oostra, B A, Elliott, P, Ruokonen, A, Sabatti, C, Gieger, C, Meitinger, T, Kronenberg, F, Döring, A, Wichmann, H-E, Smit, J H, McCarthy, M I, van Duijn, C M, Peltonen, L & Consortium, ENGAGE 2008, ' Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts ', Nature Genetics, vol. 41, no. 1, pp. 47-55 . https://doi.org/10.1038/ng.269
Aulchenko, Y S, Ripatti, S, Lindqvist, I, Boomsma, D I, Heid, I M, Pramstaller, P P, Penninx, B W J H, Janssen, A C J W, Wilson, J F, Spector, T, Martin, N G, Pedersen, N L, Kyvik, K O, Kaprio, J, Hofman, A, Freimer, N B, Jarvelin, M-R, Gyllensten, U, Campbell, H, Rudan, I, Johansson, A, Marroni, F, Hayward, C, Vitart, V, Jonasson, I, Pattar, C, Wright, A, Hastie, N, Pichler, I, Hicks, A A, Falchi, M, Willemsen, G, Hottenga, J J, de Geus, E J C, Montgomery, GW, Whitfield, J, Magnusson, P, Saharinen, J, Perola, M, Silander, K, Isaacs, A, Sijbrands, E J G, Uitterlinden, A G, Witteman, J C M, Oostra, B A, Elliott, P, Ruokonen, A, Sabatti, C, Gieger, C, Meitinger, T, Kronenberg, F, Döring, A, Wichmann, H-E, Smit, J H, McCarthy, M I, van Duijn, C M & Peltonen, L 2009, ' Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts ', Nature Genetics, vol. 41, no. 1, pp. 47-55 . https://doi.org/10.1038/ng.269
Nature Genetics
Nature Genetics, 41(1), 47-55. Nature Publishing Group
Aulchenko, Y S, Ripatti, S, Lindqvist, I, Boomsma, D, Heid, I M, Pramstaller, P P, Penninx, B W J H, Janssens, A C J W, Wilson, J F, Spector, T, Martin, N G, Pedersen, N L, Kyvik, K O, Kaprio, J, Hofman, A, Freimer, N B, Jarvelin, M-R, Gyllensten, U, Campbell, H, Rudan, I, Johansson, A, Marroni, F, Hayward, C, Vitart, V, Jonasson, I, Pattaro, C, Wright, A, Hastie, N, Pichler, I, Hicks, A A, Falchi, M, Willemsen, G, Hottenga, J-J, de Geus, E J C, Montgomery, G W, Whitfield, J, Magnusson, P, Saharinen, J, Perola, M, Silander, K, Isaacs, A, Sijbrands, E J G, Uitterlinden, A G, Witteman, J C M, Oostra, B A, Elliott, P, Ruokonen, A, Sabatti, C & Gieger, C & Meitinger, T 2009, ' Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts ', Nature Genetics, vol. 41, no. 1, pp. 47-55 . https://doi.org/10.1038/ng.269
Aulchenko, Y S, Ripatti, S, Lindqvist, I, Boomsma, D, Heid, I M, Pramstaller, P P, Penninx, B W J H, Janssens, A C J W, Wilson, J F, Spector, T, Martin, N G, Pedersen, N L, Kyvik, K O, Kaprio, J, Hofman, A, Freimer, N B, Jarvelin, M-R, Gyllensten, U, Campbell, H, Rudan, I, Johansson, A, Marroni, F, Hayward, C, Vitart, V, Jonasson, I, Pattaro, C, Wright, A, Hastie, N, Pichler, I, Hicks, A A, Falchi, M, Willemsen, G, Hottenga, J-J, de Geus, E J C, Montgomery, G W, Whitfield, J, Magnusson, P, Saharinen, J, Perola, M, Silander, K, Isaacs, A, Sijbrands, E J G, Uitterlinden, A G, Witteman, J C M, Oostra, B A, Elliott, P, Ruokonen, A, Sabatti, C, Gieger, C, Meitinger, T, Kronenberg, F, Döring, A, Wichmann, H-E, Smit, J H, McCarthy, M I, van Duijn, C M, Peltonen, L & Consortium, ENGAGE 2008, ' Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts ', Nature Genetics, vol. 41, no. 1, pp. 47-55 . https://doi.org/10.1038/ng.269
Aulchenko, Y S, Ripatti, S, Lindqvist, I, Boomsma, D I, Heid, I M, Pramstaller, P P, Penninx, B W J H, Janssen, A C J W, Wilson, J F, Spector, T, Martin, N G, Pedersen, N L, Kyvik, K O, Kaprio, J, Hofman, A, Freimer, N B, Jarvelin, M-R, Gyllensten, U, Campbell, H, Rudan, I, Johansson, A, Marroni, F, Hayward, C, Vitart, V, Jonasson, I, Pattar, C, Wright, A, Hastie, N, Pichler, I, Hicks, A A, Falchi, M, Willemsen, G, Hottenga, J J, de Geus, E J C, Montgomery, GW, Whitfield, J, Magnusson, P, Saharinen, J, Perola, M, Silander, K, Isaacs, A, Sijbrands, E J G, Uitterlinden, A G, Witteman, J C M, Oostra, B A, Elliott, P, Ruokonen, A, Sabatti, C, Gieger, C, Meitinger, T, Kronenberg, F, Döring, A, Wichmann, H-E, Smit, J H, McCarthy, M I, van Duijn, C M & Peltonen, L 2009, ' Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts ', Nature Genetics, vol. 41, no. 1, pp. 47-55 . https://doi.org/10.1038/ng.269
Nature Genetics
Recent genome-wide association (GWA) studies of lipids have been conducted in samples ascertained for other phenotypes, particularly diabetes. Here we report the first GWA analysis of loci affecting total cholesterol (TC), low-density lipoprotein (LD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab99e1c8be55715b0cafd37917c701d1
https://doi.org/10.1038/ng.269
https://doi.org/10.1038/ng.269
Autor:
Teslovich, Tanya M, Musunuru, Kiran, Smith, Albert V, Edmondson, Andrew C, Stylianou, Ioannis M, Koseki, Masahiro, Pirruccello, James P, Ripatti, Samuli, Chasman, Daniel I, Willer, Cristen J, Johansen, Christopher T, Fouchier, Sigrid W, Isaacs, Aaron, Peloso, Gina M, Barbalic, Maja, Ricketts, Sally L, Bis, Joshua C, Aulchenko, Yurii S, Thorleifsson, Gudmar, Feitosa, Mary F, Chambers, John, Orho-Melander, Marju, Melander, Olle, Johnson, Toby, Li, Xiaohui, Guo, Xiuqing, Li, Mingyao, Shin Cho, Yoon, Jin Go, Min, Jin Kim, Young, Lee, Jong-Young, Park, Taesung, Kim, Kyunga, Sim, Xueling, Twee-Hee Ong, Rick, Croteau-Chonka, Damien C, Lange, Leslie A, Smith, Joshua D, Song, Kijoung, Hua Zhao, Jing, Yuan, Xin, Luan, Jian'an, Lamina, Claudia, Ziegler, Andreas, Zhang, Weihua, Zee, Robert YL, Wright, Alan F, Witteman, Jacqueline CM, Wilson, James F, Willemsen, Gonneke, Wichmann, H-Erich, Whitfield, John B, Waterworth, Dawn M, Wareham, Nicholas J, Waeber, Gérard, Vollenweider, Peter, Voight, Benjamin F, Vitart, Veronique, Uitterlinden, Andre G, Uda, Manuela, Tuomilehto, Jaakko, Thompson, John R, Tanaka, Toshiko, Surakka, Ida, Stringham, Heather M, Spector, Tim D, Soranzo, Nicole, Smit, Johannes H, Sinisalo, Juha, Silander, Kaisa, Sijbrands, Eric JG, Scuteri, Angelo, Scott, James, Schlessinger, David, Sanna, Serena, Salomaa, Veikko, Saharinen, Juha, Sabatti, Chiara, Ruokonen, Aimo, Rudan, Igor, Rose, Lynda M, Roberts, Robert, Rieder, Mark, Psaty, Bruce M, Pramstaller, Peter P, Pichler, Irene, Perola, Markus, Penninx, Brenda WJH, Pedersen, Nancy L, Pattaro, Cristian, Parker, Alex N, Pare, Guillaume, Oostra, Ben A, O'Donnell, Christopher J, Nieminen, Markku S, Nickerson, Deborah A, Montgomery, Grant W, Meitinger, Thomas, McPherson, Ruth, McCarthy, Mark I
Publikováno v:
Nature, vol 466, iss 7307
Plasma concentrations of total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and triglycerides are among the most important risk factors for coronary artery disease (CAD) and are targets for therapeutic interv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3483cdda0a8154cf3f4f34c028b6f3e0
https://escholarship.org/uc/item/61w7w636
https://escholarship.org/uc/item/61w7w636
Autor:
Aulchenko, Yurii S., Ripatti, Samuli, Lindqvist, Ida, Boomsma, Dorret, Heid, Iris M., Pramstaller, Peter P., Penninx, Brenda W. J. H., Janssens, A., Cecile, J. W., Wilson, James F., Spector, Tim, Martin, Nicholas G., Pedersen, Nancy L., Kyvik, Kirsten Ohm, Kaprio, Jaakko, Hofman, Albert, Freimer, Nelson B., Jarvelin, Marjo-Riitta, Gyllensten, Ulf, Campbell, Harry, Rudan, Igor, Johansson, Å, Marroni, Fabio, Hayward, Caroline, Vitart, Veronique, Jonasson, Inger, Pattaro, Cristian, Wright, Alan, Hastie, Nick, Pichler, Irene, Hicks, Andrew A., Falchi, Mario, Willemsen, Gonneke, Hottenga, Jouke-Jan, de Geus, Eco J. C., Montgomery, Grant W., Whitfield, John, Magnusson, Patrik, Saharinen, Juha, Perola, Markus, Silander, Kaisa, Isaacs, Aaron, Sijbrands, Eric J. G., Uitterlinden, Andre G., Witteman, Jacqueline C. M., Oostra, Ben A., Elliott, Paul, Ruokonen, Aimo, Sabatti, Chiara, Gieger, Christian, Meitinger, Thomas, Kronenberg, Florian, Döring, Angela, Wichmann, H-Erich, Smit, Johannes H., McCarthy, Mark I., van Duijn, Cornelia M., Peltonen, Leena
Recent genome-wide association (GWA) studies of lipids have been conducted in samples ascertained for other phenotypes, particularly diabetes. Here we report the first GWA analysis of loci affecting total cholesterol (TC), low-density lipoprotein (LD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::d3114b92d1106b91e5c309e4465f2668
https://www.bib.irb.hr/377149
https://www.bib.irb.hr/377149