Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Sahar Melamed"'
Autor:
Sahar Melamed, Aixia Zhang, Michal Jarnik, Joshua Mills, Aviezer Silverman, Hongen Zhang, Gisela Storz
Publikováno v:
eLife, Vol 12 (2023)
Flagella are important for bacterial motility as well as for pathogenesis. Synthesis of these structures is energy intensive and, while extensive transcriptional regulation has been described, little is known about the posttranscriptional regulation.
Externí odkaz:
https://doaj.org/article/7d6a3952342c403b8ebaf40b1a269605
Autor:
Michaela Huber, Anne Lippegaus, Sahar Melamed, Malte Siemers, Benjamin R. Wucher, Mona Hoyos, Carey Nadell, Gisela Storz, Kai Papenfort
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Small regulatory RNAs (sRNAs) often act in concert with the RNA-chaperone Hfq to regulate the expression of multiple target transcripts in bacteria. Here, the authors identify Hfq-interacting sRNAs and their targets in the pathogen Vibrio cholerae, i
Externí odkaz:
https://doaj.org/article/f507f04b470841c69f90b04b2bd9656c
Small regulatory RNAs (sRNAs) acting in concert with the RNA chaperone Hfq are prevalent in many bacteria and typically act by base-pairing with multiple target transcripts. In the human pathogen Vibrio cholerae, sRNAs play roles in various processes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76d076ac085a8646e2f597a4bcb5cca9
Autor:
Michael J. Gebhardt, Elizabeth A. Farland, Pallabi Basu, Keven Macareno, Sahar Melamed, Simon L. Dove
Publikováno v:
Proceedings of the National Academy of Sciences. 120
The RNA chaperone Hfq plays important regulatory roles in many bacteria by facilitating the base pairing between small RNAs (sRNAs) and their cognate mRNA targets. In the gram-negative opportunistic pathogen Pseudomonas aeruginosa , over a hundred pu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a468f99ced2d322055953fcb9e0b04b
https://doi.org/10.1073/pnas.2218407120
https://doi.org/10.1073/pnas.2218407120
Autor:
Kai Papenfort, Sahar Melamed
Publikováno v:
Annual Review of Microbiology. 77
Small regulatory RNA (sRNAs) are key mediators of posttranscriptional gene control in bacteria. Assisted by RNA-binding proteins, a single sRNA often modulates the expression of dozens of genes, and thus sRNAs frequently adopt central roles in regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef25a467638bc85d4e1a20cdf4feeac1
https://doi.org/10.1146/annurev-micro-041320-025836
https://doi.org/10.1146/annurev-micro-041320-025836
Autor:
Sahar Melamed
Publikováno v:
Peer Community In Genomics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18a76411621870dba051332a422bb73b
https://doi.org/10.24072/pci.genomics.100157
https://doi.org/10.24072/pci.genomics.100157
Autor:
Sahar Melamed
Publikováno v:
Curr Genet
It is now established that base-pairing regulatory RNAs are key players in post-transcriptional regulatory networks where they affect the translation and/or stability of their target RNAs. In many cases, the base-pairing between two RNAs is facilitat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9db6dcf8f54c0a7a589bb37b70a7ac98
https://doi.org/10.1007/s00294-020-01066-y
https://doi.org/10.1007/s00294-020-01066-y
Flagella are important for bacterial motility as well as for pathogenesis. Synthesis of these structures is energy intensive and, while extensive transcriptional regulation has been described, little is known about the posttranscriptional regulation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55c8b64cd65dadfd077a6f73bef94334
https://doi.org/10.1101/2021.08.05.455139
https://doi.org/10.1101/2021.08.05.455139
Publikováno v:
Mol Cell
Base pairing RNAs modulate gene expression in all studied organisms. In many bacteria, the base pairing between most small regulatory RNAs (sRNAs) and their targets is mediated by the Hfq RNA chaperone. However, recent studies have shown FinO-domain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aaf3a98cd1088527a7a82231a12131b
https://pubmed.ncbi.nlm.nih.gov/31761494
https://pubmed.ncbi.nlm.nih.gov/31761494
Autor:
Yair E. Gatt, Niv Reiss, Yael Altuvia, Asaf Peer, Liron Argaman, Sahar Melamed, Amir Bar, Raya Faigenbaum-Romm, Hanah Margalit
Publikováno v:
Molecular Cell
Summary Small RNAs (sRNAs) associated with the RNA chaperon protein Hfq are key posttranscriptional regulators of gene expression in bacteria. Deciphering the sRNA-target interactome is an essential step toward understanding the roles of sRNAs in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfdbc185844c3209e7d2d9cea1637a86
http://europepmc.org/articles/PMC5145812
http://europepmc.org/articles/PMC5145812