Theoretical studies of the excited electronic states of the molecule ScLi and its ions ScLi± with a feasibility study of laser cooling

Autor: Sahar Kassem, Israa Zeid, Mahmoud Korek

Publikováno v: Canadian Journal of Chemistry. 101:33-42

For the transition metal lithides ScLi and ScLi±, the adiabatic potential energy and the static and transition dipole moment curves of the low-lying electronic states in the representation 2 s+1Λ(+/−) have been investigated. The spectroscopic con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::01ab4f23214aba97befc8691ad556458
https://doi.org/10.1139/cjc-2022-0134

SAR442085, a novel anti-CD38 antibody with enhanced antitumor activity against multiple myeloma

Autor: Alain Fournier, Marielle Chiron, Nadège Carrié, Sukhvinder Sidhu, Marine Cuisinier, Sahar Kassem, Dmitri Wiederschain, Hélène Bonnevaux, Jean-Luc Teillaud, Ludovic Martinet, Helgi van de Velde, Jill Corre, Isabelle Arnould, Béré K. Diallo, Nizar El-Murr, Céline Nicolazzi, Angela Virone-Oddos, Hervé Avet-Loiseau, Alexandre Tang

Publikováno v: Blood. 139:1160-1176

Anti-CD38 monoclonal antibodies (mAbs) represent a breakthrough in the treatment of multiple myeloma (MM), yet some patients fail to respond or progress quickly with this therapy, highlighting the need for novel approaches. In this study we compared

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed0517bb90aadd5eef0a42bc69ee4141
https://doi.org/10.1182/blood.2021012448

Oral Administration of the Probiotic Strain Escherichia coli Nissle 1917 Reduces Susceptibility to Neuroinflammation and Repairs Experimental Autoimmune Encephalomyelitis-Induced Intestinal Barrier Dysfunction

Autor: Thomas Secher, Sahar Kassem, Mehdi Benamar, Isabelle Bernard, Michele Boury, Frederick Barreau, Eric Oswald, Abdelhadi Saoudi

Publikováno v: Frontiers in Immunology, Vol 8 (2017)

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) with an increasing incidence in developed countries. Recent reports suggest that modulation of the gut microbiota might be one promising therapy for MS. Her

Externí odkaz: https://doaj.org/article/c50d6dc3f9944a44aa1ec1825e488114

A Natural Variant of the T Cell Receptor-Signaling Molecule Vav1 Reduces Both Effector T Cell Functions and Susceptibility to Neuroinflammation.

Autor: Sahar Kassem, Guillaume Gaud, Isabelle Bernard, Mehdi Benamar, Anne S Dejean, Roland Liblau, Gilbert J Fournié, Céline Colacios, Bernard Malissen, Abdelhadi Saoudi

Publikováno v: PLoS Genetics, Vol 12, Iss 7, p e1006185 (2016)

The guanine nucleotide exchange factor Vav1 is essential for transducing T cell antigen receptor signals and therefore plays an important role in T cell development and activation. Our previous genetic studies identified a locus on rat chromosome 9 t

Externí odkaz: https://doaj.org/article/d8479a9b003e41b78eb0bbad0088f8e1

Tissue-restricted control of established central nervous system autoimmunity by TNF receptor 2–expressing Treg cells

Autor: Cédric Auffray, Guilhem Lalle, Charlotte Pouchy, Yenkel Grinberg-Bleyer, David Sleurs, Harald Wajant, Gilles Marodon, Sylvie Grégoire, Yannis Lombardi, Bruno Lucas, Maryam Khosravi, Emilie Ronin, Gaëlle H. Martin, Noémie Chanson, Sahar Kassem, Benoît L. Salomon, Morgane Hilaire, Armanda Casrouge

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (13), pp.e2014043118. ⟨10.1073/pnas.2014043118⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2021, 118 (13), pp.e2014043118. ⟨10.1073/pnas.2014043118⟩
Proc Natl Acad Sci U S A

International audience; CD4+Foxp3+ regulatory T (Treg) cells are central modulators of autoimmune diseases. However, the timing and location of Treg cell-mediated suppression of tissue-specific autoimmunity remain undefined. Here, we addressed these

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad8cd5b547be9be536e393ec27453a4f
https://hal.sorbonne-universite.fr/hal-03185017