Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Sahar I. Da'as"'
Autor:
Viorica Chelban, Henriette Aksnes, Reza Maroofian, Lauren C. LaMonica, Luis Seabra, Anette Siggervåg, Perrine Devic, Hanan E. Shamseldin, Jana Vandrovcova, David Murphy, Anne-Claire Richard, Olivier Quenez, Antoine Bonnevalle, M. Natalia Zanetti, Rauan Kaiyrzhanov, Vincenzo Salpietro, Stephanie Efthymiou, Lucia V. Schottlaender, Heba Morsy, Annarita Scardamaglia, Ambreen Tariq, Alistair T. Pagnamenta, Ajia Pennavaria, Liv S. Krogstad, Åse K. Bekkelund, Alessia Caiella, Nina Glomnes, Kirsten M. Brønstad, Sandrine Tury, Andrés Moreno De Luca, Anne Boland-Auge, Robert Olaso, Jean-François Deleuze, Mathieu Anheim, Benjamin Cretin, Barbara Vona, Fahad Alajlan, Firdous Abdulwahab, Jean-Luc Battini, Rojan İpek, Peter Bauer, Giovanni Zifarelli, Serdal Gungor, Semra Hiz Kurul, Hanns Lochmuller, Sahar I. Da’as, Khalid A. Fakhro, Alicia Gómez-Pascual, Juan A. Botía, Nicholas W. Wood, Rita Horvath, Andreas M. Ernst, James E. Rothman, Meriel McEntagart, Yanick J. Crow, Fowzan S. Alkuraya, Gaël Nicolas, SYNaPS Study Group, Thomas Arnesen, Henry Houlden
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Primary familial brain calcification (PFBC) is characterized by calcium deposition in the brain, causing progressive movement disorders, psychiatric symptoms, and cognitive decline. PFBC is a heterogeneous disorder currently linked to varian
Externí odkaz:
https://doaj.org/article/1b66ac89bf354c83adcf4b0c6dc91661
Autor:
Sahar I. Da’as, Ikhlak Ahmed, Waseem H. Hasan, Doua A. Abdelrahman, Elbay Aliyev, Sabah Nisar, Ajaz Ahmad Bhat, Mugdha V. Joglekar, Anandwardhan A. Hardikar, Khalid A. Fakhro, Ammira S. Al-Shabeeb Akil
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-18 (2023)
Abstract Background Type 2 diabetes (T2D) is a critical healthcare challenge and priority in Qatar which is listed amongst the top 10 countries in the world, with its prevalence presently at 17% double the global average. MicroRNAs (miRNAs) are impli
Externí odkaz:
https://doaj.org/article/afaa747b6ead43949eadded2d739a741
Publikováno v:
MethodsX, Vol 8, Iss , Pp 101418- (2021)
Microinjection technique is one of the essential methodologies that are used widely in zebrafish research. Microinjection is utilized to perform genetic manipulations within the developing zebrafish model. Further, this technique is used to study a w
Externí odkaz:
https://doaj.org/article/deeded904e2f4a56ab92075adb91d927
Autor:
Sahar I. Da’as, Waleed Aamer, Waseem Hasan, Aljazi Al-Maraghi, Alya Al-Kurbi, Houda Kilani, Jehan AlRayahi, Khaled Zamel, Mitchell A. Stotland, Khalid A. Fakhro
Publikováno v:
Cells, Vol 9, Iss 8, p 1782 (2020)
Recessive mutations in Post-GPI attachment to proteins 3 (PGAP3) cause the rare neurological disorder hyperphosphatasia with mental retardation syndrome 4 type (HPMRS4). Here, we report a novel homozygous nonsense mutation in PGAP3 (c.265C>T-p.Gln89*
Externí odkaz:
https://doaj.org/article/2e1f0282cd124b28bbb6564353573ee6
Autor:
Muhammad Elnaggar, Anjud Al-Mohannadi, Waseem Hasan, Doua Abdelrahman, Mohammed J. Al-Kubaisi, Igor Pavlovski, Giusy Gentilcore, Abbirami Sathappan, Dhanya Kizhakayil, Aesha I. Ali, Suruchi Mohan, Damilola Olagunju, Chiara Cugno, Jean-Charles Grivel, Chiara Borsotti, Antonia Follenzi, Sahar I. Da’as, Sara Deola
Publikováno v:
Blood Advances. 7:697-711
Emerging gene therapy clinical trials test the correction of hemophilia A (HA) by replacing factor VIII (FVIII) in autologous hematopoietic stem cells (HSCs). Although it is known that platelets, monocyte/macrophages, and mesenchymal stromal cells ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a64bd749e91bd063020a8334b42ffec8
https://doi.org/10.1182/bloodadvances.2022009014
https://doi.org/10.1182/bloodadvances.2022009014
Autor:
Amal, Elfatih, Sahar I, Da'as, Doua, Abdelrahman, Hamdi, Mbarek, Idris, Mohammed, Waseem, Hasan, Khalid A, Fakhro, Xavier, Estivill, Zohreh, Tatari
Publikováno v:
Human Molecular Genetics. 31:2796-2809
In order to report clinically actionable incidental findings in genetic testing, the American College of Medical Genetics and Genomics (ACMG) recommended the evaluation of variants in 59 genes associated with highly penetrant mutations. However, ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eff74a0f681acd43f776da08ee976df1
https://doi.org/10.1093/hmg/ddac073
https://doi.org/10.1093/hmg/ddac073
Autor:
Nadin Younes, Bana S Alsahan, Asmaa J Al-Mesaifri, Sahar I Da’as, Gianfranco Pintus, Amin F Majdalawieh, Gheyath K Nasrallah
Publikováno v:
Toxicol Res (Camb)
Background A sensitive method to investigate cellular stress and cytotoxicity is based on measuring mitochondrial membrane potential. Recently, JC-10, was developed to measure mitochondrial membrane potential in vitro and used as an indicator for cyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d2865012aea6560d9fe5c33cd82bc34
https://doi.org/10.1093/toxres/tfab114
https://doi.org/10.1093/toxres/tfab114
Autor:
Khalid A. Fakhro, Doua Abdelrahman, Laila A. Jerman, Waseem Hasan, Ammira S. Akil, Sahar I. Da'as
Publikováno v:
Diabetes. 70
MicroRNAs (miRNAs/miRs) are implicated in the pathogenesis of type 2 diabetes (T2D) and its long-term complications such as retinopathy. miRNAs circulating levels have explored as possible biomarkers for the advancement of T2D. We examined the expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f92d57a0fb603be04f1f1212177307e6
https://doi.org/10.2337/db21-437-p
https://doi.org/10.2337/db21-437-p
Autor:
Luis R. Saraiva, Diogo Manoel, Richard C. Gerkin, Senthil Selvaraj, Abbirami Sathappan, Charles J. Arayata, Reem Hasnah, Sahar I. Da'as, Joel D. Mainland, Melanie Makhlouf, Doua Abdelrahman
Publikováno v:
Curr Biol
Odor perception in non-humans is poorly understood. Here, we generated the most comprehensive mouse olfactory ethological atlas to date, consisting of behavioral responses to a diverse panel of 73 odorants, including 12 at multiple concentrations. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b20a4405e858690996e435b87b005844
https://pubmed.ncbi.nlm.nih.gov/33957076
https://pubmed.ncbi.nlm.nih.gov/33957076
Autor:
Gianfranco Pintus, Gheyath K. Nasrallah, Aboubakr M. Abdullah, Houria Ech-Cherif, Amin F. Majdalawieh, Nadin Younes, Sahar I. Da'as, Maha Al-Asmakh, Mostafa H. Sliem, A. Bahgat Radwan
Publikováno v:
Environmental Sciences Europe. 32
Background Fatty alcohol polyoxyethylene ether-7 (AEO-7), a non-ionic surfactant, has recently been receiving extensive attention from the ocean pipeline industry for its ability to inhibit corrosion. However, the present lack of information concerni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0fe7774c052f620b688a366e55f759e
https://doi.org/10.1186/s12302-020-00429-z
https://doi.org/10.1186/s12302-020-00429-z