Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Sahar Awwad"'
Autor:
Thomas D. Pollard, Iria Seoane-Viaño, Jun Jie Ong, Patricija Januskaite, Sahar Awwad, Mine Orlu, Manuel F. Bande, Abdul W. Basit, Alvaro Goyanes
Publikováno v:
International Journal of Pharmaceutics: X, Vol 5, Iss , Pp 100150- (2023)
Inkjet printing has the potential to advance the treatment of eye diseases by printing drugs on demand onto contact lenses for localised delivery and personalised dosing, while near-infrared (NIR) spectroscopy can further be used as a quality control
Externí odkaz:
https://doaj.org/article/a911663bc8dc4ae3ac3e8de22cee9e92
Autor:
Sahar Awwad, Nkiruka Ibeanu, Tianyang Liu, Angeliki Velentza-Almpani, Nerisha Chouhan, Stavros Vlatakis, Peng Tee Khaw, Steve Brocchini, Yann Bouremel
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1444 (2023)
Real-time measurement is important in modern dissolution testing to aid in parallel drug characterisation and quality control (QC). The development of a real-time monitoring platform (microfluidic system, a novel eye movement platform with temperatur
Externí odkaz:
https://doaj.org/article/5cda3c065e3241bdb3d5bbe7224b32bc
Autor:
Angeliki Velentza-Almpani, Nkiruka Ibeanu, Tianyang Liu, Christopher Redhead, Peng Tee Khaw, Steve Brocchini, Sahar Awwad, Yann Bouremel
Publikováno v:
Pharmaceutics, Vol 14, Iss 6, p 1267 (2022)
New in vitro prototypes (PK-Eye™) were tested with and without eye movement to understand diffusion and convection effects on intraocular clearance. Port placement in front ((i) ciliary inflow model) and behind the model lens ((ii) posterior inflow
Externí odkaz:
https://doaj.org/article/5784d17649fd4197b1262c8e4f4b4bcf
Autor:
Xiaoyan Xu, Sahar Awwad, Luis Diaz-Gomez, Carmen Alvarez-Lorenzo, Steve Brocchini, Simon Gaisford, Alvaro Goyanes, Abdul W. Basit
Publikováno v:
Pharmaceutics, Vol 13, Iss 9, p 1421 (2021)
Dry eye disease is a common ocular disorder that is characterised by tear deficiency or excessive tear evaporation. Current treatment involves the use of eye drops; however, therapeutic efficacy is limited because of poor ocular bioavailability of to
Externí odkaz:
https://doaj.org/article/37afcfac38aa4eb780f4a57aad3c42aa
Autor:
Nkiruka Ibeanu, Raphael Egbu, Lesley Onyekuru, Hoda Javaheri, Peng Tee Khaw, Gareth R. Williams, Steve Brocchini, Sahar Awwad
Publikováno v:
Pharmaceutics, Vol 12, Iss 10, p 999 (2020)
Proteins and peptides have emerged in recent years to treat a wide range of multifaceted diseases such as cancer, diabetes and inflammation. The emergence of polypeptides has yielded advancements in the fields of biopharmaceutical production and form
Externí odkaz:
https://doaj.org/article/fcfff3951e084046acbebc214f2df601
Publikováno v:
British Journal of Pharmacy, Vol 2, Iss 1 (2017)
There is a need to prolong drug residence time using a biocompatible formulation in the subconjunctival space after surgery to treat glaucoma. Drug releasing discs were prepared with 2-(hydroxyethyl)methacrylate (HEMA) and 2-methacryloyl-oxyethyl pho
Externí odkaz:
https://doaj.org/article/d4db7dfd99db4c09803d17f5efed13c2
Autor:
Christin Henein, Sahar Awwad, Nkiruka Ibeanu, Stavros Vlatakis, Steve Brocchini, Peng Tee Khaw, Yann Bouremel
Publikováno v:
Pharmaceutics, Vol 11, Iss 8, p 371 (2019)
Intravitreal injections have become the cornerstone of retinal care and one of the most commonly performed procedures across all medical specialties. The impact of hydrodynamic forces of intravitreal solutions when injected into vitreous or vitreous
Externí odkaz:
https://doaj.org/article/d9a2e32606334085aed07e65067000be
Autor:
Sahar Awwad, Ukrit Angkawinitwong
Publikováno v:
Pharmaceutics, Vol 10, Iss 3, p 83 (2018)
Monoclonal antibodies (mAbs) are one of the most important classes of therapeutic proteins, which are used to treat a wide number of diseases (e.g., oncology, inflammation and autoimmune diseases). Monoclonal antibody technologies are continuing to e
Externí odkaz:
https://doaj.org/article/b2b33de119054a6e9d457092a26ca38d
Publikováno v:
Frontiers in Drug Delivery. 2
Knowledge of drug mass transfer from the anterior chamber via the iris-lens barrier has important implications for the development of front of the eye medicines that can also deliver drugs to the vitreous cavity. Here, the design and evaluation of a
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 153:130-149
The majority of blinding conditions arise due to chronic pathologies in the retina. During the last two decades, antibody-based medicines administered by intravitreal injection directly into the back of the eye have revolutionised the treatment of ch