Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Sahar, Razmjooei"'
Autor:
Masuyo Miyake, Kentaro Miyake, Qinghong Han, Kentaro Igarashi, Kei Kawaguchi, Maryam Barangi, Tasuku Kiyuna, Norihiko Sugisawa, Takashi Higuchi, Hiromichi Oshiro, Zhiying Zhang, Sahar Razmjooei, Michael Bouvet, Itaru Endo, Robert M. Hoffman
Publikováno v:
Biochemical and biophysical research communications. 643
Gastric cancer is highly malignant and recalcitrant to first line chemotherapies that include 5-fluorouracil (5-FU). Cancer cells are addicted to methionine for their proliferation and survival. Methionine addiction of cancer is known as the Hoffman
Autor:
Kentaro Miyake, Yasunori Tome, Jun Ho Park, Hiromichi Oshiro, Robert M. Hoffman, Sahar Razmjooei, Fuminori Kanaya, Takashi Higuchi, Kotaro Nishida, Norihiko Sugisawa, Zhiying Zhang
Publikováno v:
Anticancer Research. 41:635-640
Background A mouse model of metastatic osteosarcoma is imperative to identify effective agents for metastatic osteosarcoma, which is a recalcitrant disease. In the present study, we established osteosarcoma patient-derived cells (OS-PDCs) and transfe
Autor:
Hiroyuki Tsuchiya, Kentaro Miyake, Shinji Miwa, Sahar Razmjooei, Norihiko Sugisawa, Michael Bouvet, Katsuhiro Hayashi, Junho Park, Zhiying Zhang, Hiroaki Kimura, Shree Ram Singh, Takashi Higuchi, Robert M. Hoffman, Norio Yamamoto, Qinghong Han, Hiromichi Oshiro, Kentaro Igarashi, Yuying Tan, Sant P. Chawla
Publikováno v:
Anticancer Research. 39:4653-4657
Background/aim Osteosarcoma is a recalcitrant neoplasm which occurs predominantly in adolescents and young adults. Recently, using a patient-derived orthotopic xenograft (PDOX) model of malignant soft-tissue sarcoma (STS), we showed that oral recombi
Autor:
Qinghong Han, Kentaro Miyake, Yasunori Tome, Sang Nam Yoon, Thinzar M. Lwin, Fuminori Kanaya, Michael Bouvet, Bryan M. Clary, Robert M. Hoffman, Zhiying Zang, Yuki Katsuya, Hiromichi Oshiro, Tasuku Kiyuna, Jun Ho Park, Sahar Razmjooei, Takashi Higuchi, Kotaro Nishida, Yuying Tan, Shree Ram Singh, Norihiko Sugisawa
Publikováno v:
Anticancer Research. 39:4667-4671
BACKGROUND/AIM Liver metastasis in colorectal-cancer is a recalcitrant disease. To develop precision individualized therapy of this disease, we developed a patient-derived orthotopic xenograft (PDOX) model of colorectal-cancer liver metastasis. In th
Autor:
Kentaro Miyake, Jun Yamamoto, Jose Reynoso, Sahar Razmjooei, Zhiying Zhang, Takashi Higuchi, Shree Ram Singh, Jun Ho Park, Hiromichi Oshiro, Norihiko Sugisawa, Bryan M. Clary, Ming Zhao, Robert M. Hoffman, Michael Bouvet
Publikováno v:
Anticancer Research. 39:3463-3467
BACKGROUND/AIM Patient-derived orthotopic xenograft (PDOX) models have patient-like clinical features and may be imaged, in case of some cancers, by passaging of the tumors through transgenic nude mice expressing red-fluorescent protein (RFP) where t
Autor:
Norihiko Sugisawa, Kentaro Miyake, Katsuhiro Hayashi, Hiroaki Kimura, Norio Yamamoto, Sahar Razmjooei, Shinji Miwa, Kentaro Igarashi, Takashi Higuchi, Robert M. Hoffman, Hiroyuki Tsuchiya, Hiromichi Oshiro, Zhiying Zhang, Shree Ram Singh, Michael Bouvet
Publikováno v:
Cancer Letters. 451:122-127
Olaratumab (OLA), a monoclonal antibody against platelet-derived growth factor receptor alpha (PDGFRα), has recently been used against soft-tissue sarcoma (STS) combined with doxorubicin (DOX), with limited efficacy. The goal of the present study wa
Autor:
Masuyo Miyake, Zhiying Zang, Hiromichi Oshiro, Kentaro Miyake, Kei Kawaguchi, Shree Ram Singh, Sahar Razmjooei, Yasunori Tome, Maryam Barangi, Tasuku Kiyuna, Robert M. Hoffman, Scott D. Nelson, Yunfeng Li, Fuminori Kanaya, Michael Bouvet, Sintawat Wangsiricharoen, Takashi Higuchi
Publikováno v:
Tissue and Cell. 58:17-23
Follicular dendritic cell sarcoma (FDCS) is a very rare and highly recalcitrant disease. A patient's doxorubicin-resistant FDCS was previously established orthotopically on the right high thigh into the biceps femoris of mice to establish a patient-d
Autor:
Robert M. Hoffman, Michael Bouvet, Hiroaki Kimura, Takashi Higuchi, Shinji Miwa, Sahar Razmjooei, Hiroyuki Tsuchiya, Zhiying Zhang, Shree Ram Singh, Hiromichi Oshiro, Norio Yamamoto, Kentaro Igarashi, Norihiko Sugisawa, Kentaro Miyake, Katsuhiro Hayashi
Publikováno v:
Cancer Chemotherapy and Pharmacology. 83:1075-1082
Olaratumab (OLA) is a monoclonal antibody against platelet-derived growth factor receptor alpha. OLA has recently been used against soft-tissue sarcoma (STS) combined with doxorubicin (DOX), but with limited efficacy. The goal of present study was to
Autor:
Kei Kawaguchi, Ryusei Matsuyama, Zhiying Zhang, Kentaro Miyake, Shree Ram Singh, Robert M. Hoffman, Scott D. Nelson, Takashi Higuchi, Masuyo Miyake, Tasuku Kiyuna, Yukihiko Hiroshima, Sahar Razmjooei, Takafumi Kumamoto, Sintawat Wangsiricharoen, Hiromichi Oshiro, Michael Bouvet, Sant P. Chawla, Itaru Endo, Takashi Murakami, Yunfeng Li
Publikováno v:
Biochemical and Biophysical Research Communications. 509:1041-1046
There are no effective treatments for leiomyosarcoma (LMS) spreading intraabdominally. The aim of this study was to develop precision chemotherapy for recurrent peritoneal LMS metastases in a patient-derived orthotopic xenograft (PDOX) model. The LMS
Autor:
Robert M. Hoffman, Michael Bouvet, Tasuku Kiyuna, Hiromichi Oshiro, Scott D. Nelson, Takashi Higuchi, Yunfeng Li, Kentaro Miyake, Yasunori Tome, Sahar Razmjooei, Sintawat Wangsiricharoen, Maryam Barangi, Fuminori Kanaya, Masuyo Miyake, Zhiying Zhang, Shree Ram Singh, Kei Kawaguchi
Publikováno v:
Anticancer research. 39(1):81-85
Background/aim Undifferentiated pleomorphic sarcoma (UPS) is a common soft tissue sarcoma and highly recalcitrant. We have previously developed patient-derived orthotopic xenograft (PDOX) mouse models of UPS and other major sarcoma types. Unlike PDOX