Zobrazeno 1 - 10
of 894
pro vyhledávání: '"Sahakian, BJ"'
Autor:
Lim, TV, Cardinal, RN, Meng, C, Murray, GK, Craig, KJ, Abbott, S, Shabbir, SS, Suckling, J, Sahakian, BJ, Bullmore, ET, Robbins, TW, Ersche, KD
Background: Chronic stimulant use has been associated with disruptions in fronto-striatal systems implicated in as- sociative learning [1]. Experimental studies have also shown that individuals with stimulant drug addiction experience difficulties in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3ee7ea28176ad9110b126ad88012c3b
Publikováno v:
Cerebrospinal Fluid Research, Vol 3, Iss Suppl 1, p S30 (2006)
Externí odkaz:
https://doaj.org/article/b49e12417ed7489682ece64acea97544
Autor:
Nestor, LJ, Paterson, LM, Murphy, A, McGonigle, J, Orban, C, Reed, L, Taylor, E, Flechais, R, Smith, D, Bullmore, ET, Ersche, KD, Suckling, J, Elliott, R, Deakin, B, Rabiner, I, Lingford Hughes, A, Sahakian, BJ, Robbins, TW, Nutt, DJ
Identifying key neural substrates in addiction disorders for targeted drug development remains a major challenge for clinical neuroscience. One emerging target is the opioid system, where substance‐dependent populations demonstrate prefrontal opioi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1032::158369db08dd1882018856bc20795f17
http://hdl.handle.net/10044/1/64321
http://hdl.handle.net/10044/1/64321
Autor:
Morris, LS, Baek, K, Tait, R, Elliott, R, Ersche, KD, Flechais, R, McGonigle, J, Murphy, A, Nestor, LJ, Orban, C, Passetti, F, Paterson, LM, Rabiner, I, Reed, L, Smith, D, Suckling, J, Taylor, EM, Bullmore, ET, Lingford-Hughes, AR, Deakin, B, Nutt, DJ, Sahakian, BJ, Robbins, TW, Voon, V, ICCAM Consortium
Naltrexone, an opioid receptor antagonist, is commonly used as a relapse prevention medication in alcohol and opiate addiction, but its efficacy and the mechanisms underpinning its clinical usefulness are not well characterized. In the current study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::dcc04f40c9606cb13446a01bf0b2316e
https://www.repository.cam.ac.uk/handle/1810/263857
https://www.repository.cam.ac.uk/handle/1810/263857
Autor:
Rae, CL, Rodríguez, PV, Ye, Z, Hughes, LE, Jones, PS, Ham, T, Rittman, T, Coyle-Gilchrist, I, Regenthal, R, Sahakian, BJ, Barker, RA, Robbins, TW, Rowe, JB
Parkinson's disease impairs the inhibition of responses, and whilst impulsivity is mild for some patients, severe impulse control disorders affect ∼10% of cases. Based on preclinical models we proposed that noradrenergic denervation contributes to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6cdbb5f06b3a0082ff2f5f57eea884c
Autor:
Chuang, J-Y, Hagan, CC, Murray, GK, Graham, JME, Ooi, C, Tait, R, Holt, RJ, Elliott, R, van Nieuwenhuizen, AO, Bullmore, ET, Lennox, BR, Sahakian, BJ, Goodyer, IM, Suckling, J
Publikováno v:
Frontiers in Psychiatry
Chuang, J-Y, Hagan, C C, Murray, G K, Graham, J M E, Ooi, C, Tait, R, Holt, R J, Elliott, R, van Nieuwenhuizen, A O, Bullmore, E T, Lennox, B R, Sahakian, B J, Goodyer, I M & Suckling, J 2017, ' Adolescent major depressive disorder : Neuroimaging evidence of sex difference during an affective Go/No-Go task ', Frontiers in Psychiatry, vol. 8, no. JUL, 119 . https://doi.org/10.3389/fpsyt.2017.00119
Chuang, J-Y, Hagan, C C, Murray, G K, Graham, J M E, Ooi, C, Tait, R, Holt, R J, Elliott, R, van Nieuwenhuizen, A O, Bullmore, E T, Lennox, B R, Sahakian, B J, Goodyer, I M & Suckling, J 2017, ' Adolescent major depressive disorder : Neuroimaging evidence of sex difference during an affective Go/No-Go task ', Frontiers in Psychiatry, vol. 8, no. JUL, 119 . https://doi.org/10.3389/fpsyt.2017.00119
Compared to female major depressive disorder (MDD), male MDD often receives less attention. However, research is warranted since there are significant sex differences in the clinical presentation of MDD and a higher rate of suicide in depressed men.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e0537f6ac05dbcee6f56a593e1dbbc5b
http://europepmc.org/articles/PMC5504124
http://europepmc.org/articles/PMC5504124
Autor:
Savulich, G, Riccelli, R, Passamonti, L, Correia, M, Deakin, JFW, Elliott, R, Flechais, RSA, Lingford-Hughes, AR, McGonigle, J, Murphy, A, Nutt, DJ, Orban, C, Paterson, LM, Reed, LJ, Smith, DG, Suckling, J, Tait, R, Taylor, EM, Sahakian, BJ, Robbins, TW, Ersche, KD, ICCAM Platform
Naltrexone is an opioid receptor antagonist used in the management of alcohol dependence. Although the endogenous opioid system has been implicated in emotion regulation, the effects of mu-opioid receptor blockade on brain systems underlying negative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfb3a3ea2555af9c59e2aa9bd1659599
https://www.repository.cam.ac.uk/handle/1810/263548
https://www.repository.cam.ac.uk/handle/1810/263548
Background:\ud There is evidence of executive function impairment in obsessive compulsive disorder (OCD) that potentially contributes to symptom development and maintenance. Nevertheless, the precise nature of these executive impairments and their ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::45fa51a0317132f6a08d11414d66b2d6
Publikováno v:
Clinical Pharmacology & Therapeutics; Feb2017, Vol. 101 Issue 2, p170-172, 3p
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