Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sahadia Koop"'
Autor:
Rama Khokha, Marsha Grattan, Ann F. Chambers, Vincent L. Morris, James Leone, Ian C. MacDonald, E. E. Schmidt, Sahadia Koop, Alan C. Groom
Publikováno v:
Proceedings of the National Academy of Sciences. 93:11080-11084
Escape of cancer cells from the circulation (extravasation) is thought to be a major rate-limiting step in metastasis, with few cells being able to extravasate. Furthermore, highly metastatic cells are believed to extravasate more readily than poorly
Autor:
Alan C. Groom, E. E. Schmidt, Vincent L. Morris, Ian C. MacDonald, Rama Khokha, Ann F. Chambers, Sahadia Koop
Publikováno v:
Cancer and Metastasis Reviews. 14:279-301
Metastases are responsible for the majority of failures in cancer treatment. Clarifying steps in metastasis and their molecular mechanisms will be important for the development of anti-metastasis therapeutic strategies. Considerable progress has been
Autor:
Alan C. Groom, Sahadia Koop, Ian C. MacDonald, E. E. Schmidt, Ann F. Chambers, Vincent L. Morris, Marsha Grattan, Dean H. Percy
Publikováno v:
Clinical & Experimental Metastasis. 12:357-367
We examined the extravasation and subsequent migration and growth of murine mammary tumor cell lines (D2A1 and D2.OR) which differ in their metastatic ability in lung and liver, invasiveness in vitro and expression of the cysteine proteinase cathepsi
Autor:
Alan C. Groom, E. E. Schmidt, Ian C. MacDonald, Ann F. Chambers, Vincent L. Morris, Sahadia Koop
Publikováno v:
Clinical & Experimental Metastasis. 11:377-390
Biomechanical interactions of cancer cells with the microvasculature were studied using high resolution intravital videomicroscopy. We compared initial arrest of murine B16F10 melanoma and D2A1 mammary carcinoma cells fluorescently labelled with calc
Autor:
Vincent L. Morris, Ian C. MacDonald, Sahadia Koop, Eric E. Schmidt, Ann F. Chambers, Alan C. Groom
Publikováno v:
Clinical & Experimental Metastasis. 11:433-436
Autor:
Sahadia Koop, Marsha Grattan, Mary Ann McLane, Vincent L. Morris, Stefan Niewiarowski, E. E. Schmidt, Rama Khokha, Alan C. Groom, Ian C. MacDonald, Ann F. Chambers
Publikováno v:
Experimental cell research. 219(2)
Adhesion molecules, including integrins, are important for interactions of cancer cells with vessel walls, a step leading to cancer metastasis. Disintegrins block the action of integrins by binding to them. We tested the hypothesis that the disintegr