Zobrazeno 1 - 10
of 203
pro vyhledávání: '"Sagnik, Sen"'
Publikováno v:
Indian Journal of Ophthalmology, Vol 72, Iss Suppl 5, Pp S752-S757 (2024)
Purpose: To report real-world clinical evidence of brolucizumab in treating neovascular age-related macular degeneration (nAMD). Methods: This study included 37 eyes with nAMD treated with intravitreal injections of brolucizumab. The main outcomes we
Externí odkaz:
https://doaj.org/article/421923ed9d1d49969e49f90204c4a844
Autor:
Yee Ling Wong, Shiao Wei Wong, Darren S.J. Ting, Alankrita Muralidhar, Sagnik Sen, Olivia Schaff, Hannah Istre-Wilz, Barbara Erny
Publikováno v:
The Journal of Climate Change and Health, Vol 15, Iss , Pp 100296- (2024)
Climate change represents a significant global health crisis, characterized by a complex interplay of environmental shifts and interconnected phenomena. These alterations have given rise to a multitude of health implications, notably impacting ocular
Externí odkaz:
https://doaj.org/article/c7a47d6f1d8743ccb2277f7b00254555
Autor:
Vishnu Udayakumaran Nair Sunitha Kumary, Bryan J. Venters, Karthikeyan Raman, Sagnik Sen, Pierre-Olivier Estève, Martis W. Cowles, Michael-Christopher Keogh, Sriharsa Pradhan
Publikováno v:
Epigenomes, Vol 8, Iss 2, p 20 (2024)
Nucleosomes are non-uniformly distributed across eukaryotic genomes, with stretches of ‘open’ chromatin strongly associated with transcriptionally active promoters and enhancers. Understanding chromatin accessibility patterns in normal tissue and
Externí odkaz:
https://doaj.org/article/e53eb90ce84a4073af3fe36178d2c68d
Autor:
Sagnik Sen, Prithviraj Udaya, Jayapal Jeya Maheshwari, Piyush Kohli, Haemoglobin Parida, Naresh Babu Kannan, Kim Ramasamy, Kuppamuthu Dharmalingam
Publikováno v:
Indian Journal of Ophthalmology, Vol 71, Iss 8, Pp 3069-3079 (2023)
Purpose: To explore the vitreous humor proteome from type 2 diabetes subjects with proliferative diabetic retinopathy (PDR) in the Indian population. Methods: We performed mass spectrometry-based label-free quantitative analysis of vitreous proteome
Externí odkaz:
https://doaj.org/article/fd2e0dca6a124dd1960650f765a5c225
Autor:
Sagnik Sen, Prithviraj Udaya, Jayapal J Maheshwari, Kim Ramasamy, Naresh B Kannan, Kuppamuthu Dharmalingam
Publikováno v:
Indian Journal of Ophthalmology, Vol 71, Iss 5, Pp 2027-2040 (2023)
Purpose: To analyze and describe the proteome of the vitreous humour in eyes with idiopathic macular holes. Methods: We performed mass spectrometry (MS)-based label-free quantitative analysis of the vitreous proteome of idiopathic macular hole (IMH)
Externí odkaz:
https://doaj.org/article/3078a67f08304fa3b37762afc46d501a
Autor:
Pierre-Olivier Estève, Sagnik Sen, Udayakumar S. Vishnu, Cristian Ruse, Hang Gyeong Chin, Sriharsa Pradhan
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-18 (2022)
SET8 is post-translationally poly ADPribosylated by PARP1 on several lysine residues, leading to SET8 degradation via ubiquitylation and genome-wide aberrant H4K20 methylation.
Externí odkaz:
https://doaj.org/article/99363f409dd743ae9dcafbee136ff4b4
Autor:
Melanie Ehrlich, Kenneth C. Ehrlich, Michelle Lacey, Carl Baribault, Sagnik Sen, Pierre-Olivier Estève, Sriharsa Pradhan
Publikováno v:
Epigenomes, Vol 8, Iss 1, p 4 (2024)
While studying myoblast methylomes and transcriptomes, we found that CDH15 had a remarkable preference for expression in both myoblasts and cerebellum. To understand how widespread such a relationship was and its epigenetic and biological correlates,
Externí odkaz:
https://doaj.org/article/b2b350e91e1e4b9dae196f11679323cf
Autor:
Sagnik Sen, Sobha Sivaprasad
Publikováno v:
Kerala Journal of Ophthalmology, Vol 34, Iss 2, Pp 98-103 (2022)
The classification of diabetic retinopathy has been based on 7-field photographs. With advances in retinal imaging, there is an unmet need to reclassify this condition as new predictive factors have been identified in the peripheral retina. In additi
Externí odkaz:
https://doaj.org/article/fda64dba8b504891b288be103e464555
Autor:
Sagnik Sen, Michel Michaelides, Andrew R Webster, Konstantinos Balaskas, Kaoru Fujinami, Manuel Gomes, Nikolas Pontikos, Susan M Downes, Malena Daich Varela, Omar A Mahroo, Thales Antonio Cabral de Guimaraes, Stephen Archer, Gavin Arno, Mital Shah, Savita Madhusudhan, Quang Nguyen, William Woof, Nathaniel Kabiri, Dayyanah Sumodhee, Ismail Moghul, Saoud Al-Khuzaei, Yichen Liu, Catherine Hollyhead, Bhavna Tailor, Loy Lobo, Carl Veal, Jennifer Furman
Publikováno v:
BMJ Open, Vol 13, Iss 3 (2023)
Introduction Inherited retinal diseases (IRD) are a leading cause of visual impairment and blindness in the working age population. Mutations in over 300 genes have been found to be associated with IRDs and identifying the affected gene in patients b
Externí odkaz:
https://doaj.org/article/5945d6aef20f41bfa056c55a51aabb6a
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Parkinson’s disease is a common neurodegenerative disease. The differential expression of alpha-synuclein within Lewy Bodies leads to this disease. Some missense mutations of alpha-synuclein may resultant in functional aberrations. In this
Externí odkaz:
https://doaj.org/article/ca44653ca77f4ff5a48af0756641bcf0