Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Sagie Wagage"'
Autor:
Florian Wanke, Simon Gutbier, Anna Rümmelin, Malte Steinberg, Lindsey D. Hughes, Mascha Koenen, Juliana Komuczki, Daniel Regan-Komito, Sagie Wagage, Julia Hesselmann, Ralf Thoma, Doris Brugger, Tony Christopeit, Hayian Wang, Floriane Point, Remy Hallet, Sourav Ghosh, Carla V. Rothlin, Christoph Patsch, Barbara Geering
Publikováno v:
Cell Death and Disease, Vol 12, Iss 6, Pp 1-13 (2021)
Abstract Removal of apoptotic cells by phagocytes (also called efferocytosis) is a crucial process for tissue homeostasis. Professional phagocytes express a plethora of surface receptors enabling them to sense and engulf apoptotic cells, thus avoidin
Externí odkaz:
https://doaj.org/article/01cf059ac626494a908897f862c90ad3
Autor:
Gaia Muallem, Sagie Wagage, Yan Sun, Jonathan H DeLong, Alex Valenzuela, David A Christian, Gretchen Harms Pritchard, Qun Fang, Elizabeth L Buza, Deepika Jain, M Merle Elloso, Carolina B López, Christopher A Hunter
Publikováno v:
PLoS Pathogens, Vol 13, Iss 1, p e1006173 (2017)
Respiratory paramyxoviruses are important causes of morbidity and mortality, particularly of infants and the elderly. In humans, a T helper (Th)2-biased immune response to these infections is associated with increased disease severity; however, littl
Externí odkaz:
https://doaj.org/article/fede9b5bf3fe4e05802f0a6a11661c92
Autor:
Sagie Wagage, Gretchen Harms Pritchard, Lucas Dawson, Elizabeth L Buza, Gregory F Sonnenberg, Christopher A Hunter
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0128335 (2015)
Intestinal infection with the intracellular parasite Toxoplasma gondii results in the translocation of commensal bacteria to peripheral organs and the development of a T cell response specific to the microbiota. In naïve mice, the recently described
Externí odkaz:
https://doaj.org/article/875322e40caa418db8ff7260b8590bc3
Autor:
Christopher D Dupont, David A Christian, Elizabeth M Selleck, Marion Pepper, Michael Leney-Greene, Gretchen Harms Pritchard, Anita A Koshy, Sagie Wagage, Morgan A Reuter, L David Sibley, Michael R Betts, Christopher A Hunter
Publikováno v:
PLoS Pathogens, Vol 10, Iss 4, p e1004047 (2014)
During infection with the intracellular parasite Toxoplasma gondii, the presentation of parasite-derived antigens to CD4+ and CD8+ T cells is essential for long-term resistance to this pathogen. Fundamental questions remain regarding the roles of pha
Externí odkaz:
https://doaj.org/article/2977843c3cf144dca58b9f44dc6e611a
Autor:
Adelle P McFarland, Ram Savan, Sagie Wagage, Augustina Addison, Karthika Ramakrishnan, Megan Karwan, Tri Duong, Howard A Young
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16967 (2011)
There have been conflicting reports of the role of Type I interferons (IFN) in inflammatory bowel disease (IBD). Clinical trials have shown potent efficacy of systemic interferon-beta (IFN-β) in inducing remission of ulcerative colitis. Likewise, IF
Externí odkaz:
https://doaj.org/article/4fc25fc810124f1ea73161c019dda885
Autor:
Yemsratch T. Akalu, Maria E. Mercau, Marleen Ansems, Sagie Wagage, Lindsey D. Hughes, James Nevin, Emily Alberto, Xinran Liu, Li-Zhen He, Diego Alvarado, Tibor Keler, Yong Kong, William M. Philbrick, Silvia C. Finnemann, Antonio Iavarone, Anna Lasorella, Carla V. Rothlin, Sourav Ghosh
Knockout (KO) mouse models play critical roles in elucidating biological processes behind disease-associated or disease-resistant traits. As a consequence of gene KO, mice display certain phenotypes. Based on insight into the molecular role of said g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a53afe50c86ec7173c17637695fbf5c
https://doi.org/10.1101/2022.05.23.493101
https://doi.org/10.1101/2022.05.23.493101
Autor:
Anna Rümmelin, Malte Steinberg, Ralf Thoma, Simon Gutbier, Florian Wanke, Floriane Point, Hayian Wang, Barbara Geering, Sagie Wagage, Carla V. Rothlin, Doris Brugger, Christoph Patsch, Remy Hallet, Lindsey D. Hughes, Daniel Regan-Komito, Julia Hesselmann, Tony Christopeit, Sourav Ghosh, Mascha Koenen, Juliana Komuczki
Publikováno v:
Cell Death and Disease, Vol 12, Iss 6, Pp 1-13 (2021)
Cell Death & Disease
Cell Death & Disease
Removal of apoptotic cells by phagocytes (also called efferocytosis) is a crucial process for tissue homeostasis. Professional phagocytes express a plethora of surface receptors enabling them to sense and engulf apoptotic cells, thus avoiding persist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec23ca5716b1a1ac6ad80c51c959ccc6
https://doi.org/10.1038/s41419-021-03770-0
https://doi.org/10.1038/s41419-021-03770-0
Autor:
David A. Christian, Beena John, Christopher C. Overall, Christoph Konradt, Carleigh A. O’Brien, Tajie H. Harris, Christopher A. Hunter, Aisling O’Hara Hall, Nikolas William Hayes, Sagie Wagage
Publikováno v:
The Journal of Immunology
Regulatory T cells (Tregs) play an important role in the CNS during multiple infections, as well as autoimmune inflammation, but the behavior of this cell type in the CNS has not been explored. In mice, infection with Toxoplasma gondii leads to a Th1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14a74315f16a64d26f85534e7a3a97c2
Autor:
Sagie Wagage, Christopher A. Hunter
Publikováno v:
Current Immunology Reviews. 11:43-54
Cells of the immune system utilize multiple mechanisms to respond to environmental signals and recent studies have demonstrated roles for two closely related proteins, the aryl hydrocarbon receptor (AHR) and hypoxia inducible factor-1α (HIF1α), in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01a9ab6a6121214f8f5a281ad012cc49
https://doi.org/10.2174/1573395510666141105234917
https://doi.org/10.2174/1573395510666141105234917
Autor:
M. Celeste Simon, Beena John, Louise M. Randall, Aisling O’Hara Hall, Bryan L. Krock, Sagie Wagage, Christopher L. Karp, Christopher A. Hunter
Publikováno v:
The Journal of Immunology. 192:1661-1670
The cytokine IL-10 has an important role in limiting inflammation in many settings, including toxoplasmosis. In the present studies, an IL-10 reporter mouse was used to identify the sources of this cytokine following challenge with Toxoplasma gondii.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10f8c828e9bee3593d5fc64092300b45
https://doi.org/10.4049/jimmunol.1300497
https://doi.org/10.4049/jimmunol.1300497