Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sagi Gudes"'
Publikováno v:
Nature Methods. 12:547-552
We describe a method to map the location of axonal arbors of many individual neurons simultaneously via the spectral properties of retrogradely transported dye-labeled vesicles. We inject overlapping regions of an axon target area with three or more
Publikováno v:
Journal of Neurophysiology. 113:601-619
Tetrodotoxin-resistant (TTX-r) sodium channels are key players in determining the input-output properties of peripheral nociceptive neurons. Changes in gating kinetics or in expression levels of these channels by proinflammatory mediators are likely
Autor:
Clifford J. Woolf, Felix Blasl, Jared M Sprague, Bo Duan, Haley A W Patoski, David Roberson, Sagi Gudes, Bruce P. Bean, Seog Bae Oh, Alexander M. Binshtok, Qiufu Ma, Victoria K. Robson
Publikováno v:
Nature Neuroscience. 16:910-918
The peripheral terminals of primary sensory neurons detect histamine and non-histamine itch-provoking ligands through molecularly distinct transduction mechanisms. It remains unclear, however, whether these distinct pruritogens activate the same or d
Autor:
Dimitri Fishman, Michal Hersfinkel, Yaki Caspi, Shaya Lev, Alexander M. Binshtok, Iulia I. Nita, Israel Sekler, Sagi Gudes
Publikováno v:
Biochimica et biophysica acta. 1863(12)
The nociceptive noxious heat-activated receptor - TRPV1, conducts calcium and sodium, thus producing a depolarizing receptor potential, leading to activation of nociceptive neurons. TRPV1-mediated calcium and sodium influx is negatively modulated by