Zobrazeno 1 - 10
of 1 029
pro vyhledávání: '"Saghatelian, A."'
Autor:
Eduardo Vieira de Souza, Angie L. Bookout, Christopher A. Barnes, Brendan Miller, Pablo Machado, Luiz A. Basso, Cristiano V. Bizarro, Alan Saghatelian
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract There has been a dramatic increase in the identification of non-canonical translation and a significant expansion of the protein-coding genome. Among the strategies used to identify unannotated small Open Reading Frames (smORFs) that encode
Externí odkaz:
https://doaj.org/article/13e4b549acb34d0093dff42c94e191d2
Autor:
Shuai Yan, Anna Santoro, Micah J. Niphakis, Antonio M. Pinto, Christopher L. Jacobs, Rasheed Ahmad, Radu M. Suciu, Bryan R. Fonslow, Rachel A. Herbst-Graham, Nhi Ngo, Cassandra L. Henry, Dylan M. Herbst, Alan Saghatelian, Barbara B. Kahn, Evan D. Rosen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Obesity-induced inflammation causes metabolic dysfunction, but the mechanisms remain elusive. Here we show that the innate immune transcription factor interferon regulatory factor (IRF3) adversely affects glucose homeostasis through inductio
Externí odkaz:
https://doaj.org/article/85b643d7bcf449cfb95b22f8c588eacb
Autor:
Marielle S. Köberlin, Yilin Fan, Chad Liu, Mingyu Chung, Antonio F. M. Pinto, Peter K. Jackson, Alan Saghatelian, Tobias Meyer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Lipid synthesis increases during the cell cycle to ensure sufficient membrane mass, but how insufficient synthesis restricts cell-cycle entry is not understood. Here, we identify a lipid checkpoint in G1 phase of the mammalian cell cycle by
Externí odkaz:
https://doaj.org/article/46284f4c6c074cc8a607922f662f2987
Autor:
Kim, Dong-Il, Park, Sekun, Park, Seahyung, Ye, Mao, Chen, Jane Y., Kang, Sukjae J., Jhang, Jinho, Hunker, Avery C., Zweifel, Larry S., Caron, Kathleen M., Vaughan, Joan M., Saghatelian, Alan, Palmiter, Richard D., Han, Sung
Publikováno v:
In Cell 5 September 2024 187(18):5102-5117
Autor:
Riecan, Martin, Domanska, Veronika, Lupu, Cristina, Patel, Maulin, Vondrackova, Michaela, Rossmeisl, Martin, Saghatelian, Alan, Lupu, Florea, Kuda, Ondrej
Publikováno v:
In BBA - Molecular and Cell Biology of Lipids December 2024 1869(8)
Autor:
Rocha, Andréa L., Pai, Victor, Perkins, Guy, Chang, Tina, Ma, Jiao, De Souza, Eduardo V, Chu, Qian, Vaughan, Joan M., Diedrich, Jolene K., Ellisman, Mark H., Saghatelian, Alan
Publikováno v:
In Journal of Molecular Biology 15 May 2024 436(10)
Akademický článek
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Akademický článek
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Autor:
Lucia Morgado-Palacin, Jessie A. Brown, Thomas F. Martinez, Juana M. Garcia-Pedrero, Farhad Forouhar, S. Aidan Quinn, Clara Reglero, Joan Vaughan, Yasamin Hajy Heydary, Cynthia Donaldson, Sandra Rodriguez-Perales, Eva Allonca, Rocio Granda-Diaz, Agustin F. Fernandez, Mario F. Fraga, Arianna L. Kim, Jorge Santos-Juanes, David M. Owens, Juan P. Rodrigo, Alan Saghatelian, Adolfo A. Ferrando
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
TINCR encodes a p53-regulated ubiquitin-like microprotein expressed in stratified epithelia. Tincr loss promotes UVB-induced skin carcinogenesis in mice and deletions and mutations in human squamous cell carcinoma support a tumor suppressor role.
Externí odkaz:
https://doaj.org/article/99397db4eb4344f19ba418b654b42f08
Autor:
Martinez, Thomas F., Lyons-Abbott, Sally, Bookout, Angie L., De Souza, Eduardo V., Donaldson, Cynthia, Vaughan, Joan M., Lau, Calvin, Abramov, Ariel, Baquero, Arian F., Baquero, Karalee, Friedrich, Dave, Huard, Justin, Davis, Ray, Kim, Bong, Koch, Ty, Mercer, Aaron J., Misquith, Ayesha, Murray, Sara A., Perry, Sakara, Pino, Lindsay K., Sanford, Christina, Simon, Alex, Zhang, Yu, Zipp, Garrett, Bizarro, Cristiano V., Shokhirev, Maxim N., Whittle, Andrew J., Searle, Brian C., MacCoss, Michael J., Saghatelian, Alan, Barnes, Christopher A.
Publikováno v:
In Cell Metabolism 3 January 2023 35(1):166-183