Subasumstat, a first-in-class inhibitor of SUMO-activating enzyme, demonstrates dose-dependent target engagement and SUMOylation inhibition, leading to rapid activation of innate and adaptive immune responses in the dose escalation portion of a phase 1/2 clinical study

Autor: Saggu, G., Stroopinsky, D., Arkadiusz Dudek, Olszanski, A. J., Juric, D., Dowlati, A., Vaishampayan, U., Assad, H., Rodon, J., Gibbs, J., Green, J., Du, Z., Rudicell, R., Kannan, K., Gharavi, R., Gomez-Pinillos, A., Fram, R. J., Berger, A., Sachsenmeier, K., Kasar, S.

Publikováno v: Web of Science

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08ba93032aaff6491faf5c7b9fa4c5bf
https://doi.org/10.1016/s0959-8049(22)01134-0

Chapter 22 - Fcγ receptors in autoimmunity and end-organ damage

Autor: Ernandez, T., Okubo, K., Saggu, G., Mayadas, T.N.

Publikováno v: In Systemic Lupus Erythematosus Edition: Second Edition. 2021:179-195

352 (PB132) - Subasumstat, a first-in-class inhibitor of SUMO-activating enzyme, demonstrates dose-dependent target engagement and SUMOylation inhibition, leading to rapid activation of innate and adaptive immune responses in the dose escalation portion of a phase 1/2 clinical study

Autor: Saggu, G., Stroopinsky, D., Dudek, A.Z., Olszanski, A.J., Juric, D., Dowlati, A., Vaishampayan, U., Assad, H., Rodón, J., Gibbs, J., Green, J., Du, Z., Rudicell, R., Kannan, K., Gharavi, R., Gomez-Pinillos, A., Fram, R.J., Berger, A., Sachsenmeier, K., Kasar, S.

Publikováno v: In European Journal of Cancer October 2022 174 Supplement 1:S125-S126

Contributors

Autor: Agmon-Levin, Nancy, Alarcón, Graciela S., Amengual, Olga, Ardoin, Stacy P., Arora, Swati, Atisha-Fregoso, Yemil, Atkinson, John P., Atsumi, Tatsuya, Ayoub, Isabelle, Barilla-LaBarca, Maria-Louise, Bermas, Bonnie L., Bernatsky, Sasha, Bertsias, George, Bichile, Tanmayee, Blanco, Patrick, Bohgaki, Miyuki, Bonsmann, Gisela, Borghi, Maria Orietta, Boumpas, Dimitrios T., Bourn, Rebecka, Buyon, Jill P., Caricchio, Roberto, Chan, Edward K.L., Chang, Christopher, Charrier, Manon, Chighizola, Cecilia Beatrice, Clarke, Ann E., Crispín, José C., Cuneo, Bettina, Dörner, Thomas, Damato, Erika M., Denniston, Alastair K.O., Devlin, Amy, Diamond, Betty, Ernandez, T., Falasinnu, Titilola, Fernandez-Ruiz, Ruth, Fitzpatrick, Brianna, Forbess, Lindsy, Frangou, Eleni A., Fritzler, Marvin J., Fu, Shu Man, Furie, Richard, Gaskin, Felicia, Gladman, Dafna, Gordon, Caroline, Grammer, Amrie C., Greidinger, Eric L., Greiling, Teri M., Han, Shuhong, Hansen, James E., Hasni, Sarfaraz A., Hassan, Fadi, Hedrich, Christian M., Hiromura, Keiju, Horowitz, Diane, Huang, Xin, Hunt, David, Izmirly, Peter M., James, Judith A., Jarjour, Wael N., Jefferies, Caroline A., Jefferies, Caroline, Jiang, Xiaoyue, Kaplan, Mariana J., Katsuyama, Takayuki, Khamashta, Munther, Kingsmore, Kathryn M., Koike, Takao, Kono, Dwight H., Kriegel, Martin A., Kuhn, Annegret, Kyttaris, Vasileios C, La Cava, Antonio, Ladouceur, Alexandra, Lahita, Robert G., Landmann, Aysche, Lazaro, Estibaliz, Lennard Richard, Mara L., Lino, Andreia C., Lipsky, Peter E., Liszewski, M. Kathryn, Lo, Mindy S., Lu, Qianjin, Mahieu, Mary, Malkiel, Susan, Manzi, Susan, Marder, Galina, Mayadas, T.N., Meroni, Pier Luigi, Merrill, Joan T., Mohan, Chandra, Mok, Chi Chiu, Moulton, Vaishali R., Murray, Philip I., Naffaa, Mohammad E., Nangaku, Masaomi, Niewold, Timothy, Okubo, K., Olsen, Nancy J., Pal, Trina, Paz, Ziv, Perl, Andras, Pons-Estel, Guillermo J., Qu, Bo, Rahman, Anisur, Raman, Ziaur S.M., Ramsey-Goldman, Rosalind, Reeves, Westley H., Richez, Christophe, Rosetti, Florencia, Rovin, Brad H., Rubin, Robert L., Saeli, Stephanie, Saggu, G., Sammaritano, Lisa R., Satoh, Minoru, Sawalha, Amr H., Saxena, Amit, Sciascia, Savino, Shaharir, Syahrul Sazliyana, Sharabi, Amir, Shen, Nan, Shmerling, Robert H., Simard, Julia F., Sisirak, Vanja, Slight-Webb, Samantha, Stillman, Isaac Ely, Sung, Sun-Sang J., Thakkar, Payal, Theofilopoulos, Argyrios N., Thomas, Jr, Donald E., Tissera, Hiromi, Touma, Zahi, Tsao, Betty P., Ugarte-Gil, Manuel F., Urowitz, Murray B., Vieira, Silvio Manfredo, Wainwright, Benjamin, Wallace, Daniel J., Wang, Hongyang, Wu, Haijing, Yahia, Soad Haj, Yu, C. Yung, Zhao, Zhenhuan, Zhuang, Haoyang

Publikováno v: In Systemic Lupus Erythematosus Edition: Second Edition. 2021:xxi-xxvi

Imaging In Rheumatoid Arthritis Using Liposomes Labelled With Technetium

Autor: Williams, B. D., O'sullivan, M. M., Saggu, G. S., Williams, K. E., Williams, L. A., Morgan, J. R.

Publikováno v: British Medical Journal (Clinical Research Edition), 1986 Nov 01. 293(6555), 1143-1144.

Externí odkaz: https://www.jstor.org/stable/29524994