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of 4
pro vyhledávání: '"Sage J. Allen"'
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Cells respond to DNA damage by activating signaling and DNA repair systems, described as the DNA damage response (DDR). Clarifying DDR pathways and their dysregulation in cancer are important for understanding cancer etiology, how cancer cells exploi
Externí odkaz:
https://doaj.org/article/b605f433059f48d88d8cde52045475f5
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Cells must replicate and segregate their DNA to daughter cells accurately to maintain genome stability and prevent cancer. DNA replication is usually fast and accurate, with intrinsic (proofreading) and extrinsic (mismatch repair) error-correction sy
Externí odkaz:
https://doaj.org/article/fc4c4af847e64e599107302f69a727c5
Autor:
Adi X. Mukund, Josh Tycko, Sage J. Allen, Stephanie A. Robinson, Cecelia Andrews, Connor H. Ludwig, Kaitlyn Spees, Michael C. Bassik, Lacramioara Bintu
Despite growing knowledge of the functions of individual human transcriptional effector domains, much less is understood about how multiple effector domains within the same protein combine to regulate gene expression. Here, we measure transcriptional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6caeb936c9eac3bb2ed497efb5fe771c
Publikováno v:
DNA. 2(1)
DNA replication stress is a constant threat that cells must manage to proliferate and maintain genome integrity. DNA replication stress responses, a subset of the broader DNA damage response (DDR), operate when the DNA replication machinery (replisom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db4de8cf07351d68d4aba3a1dcbc7c86
https://pubmed.ncbi.nlm.nih.gov/36203968
https://pubmed.ncbi.nlm.nih.gov/36203968