Zobrazeno 1 - 10
of 1 762
pro vyhledávání: '"Sage E"'
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Background Large-scale cohort and epidemiological studies suggest that PTSD confers risk for dementia in later life but the biological mechanisms underlying this association remain unknown. This study examined this question by assessing the
Externí odkaz:
https://doaj.org/article/9151a3a18aa041a7a311fdf3ba5f8463
Autor:
Kaitlin E. Bountress, Shannon E. Cusack, Sage E. Hawn, Andrew Grotzinger, Daniel Bustamante, Robert M. Kirkpatrick, Howard J. Edenberg, Ananda B. Amstadter
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Alcohol use (i.e., quantity, frequency) and alcohol use disorder (AUD) are common, associated with adverse outcomes, and genetically-influenced. Genome-wide association studies (GWAS) identified genetic loci associated with both. AUD is posi
Externí odkaz:
https://doaj.org/article/35657d9ed7924f69b8d432f0ce6e8795
Goal-Dependent Use of Temporal Regularities to Orient Attention under Spatial and Action Uncertainty
Publikováno v:
Journal of Cognition, Vol 7, Iss 1, Pp 37-37 (2024)
The temporal regularities in our environments support the proactive dynamic anticipation of relevant events. In visual attention, one important outstanding question is whether temporal predictions must be linked to predictions about spatial locations
Externí odkaz:
https://doaj.org/article/058f54d17b54444aa28401864fb96936
Autor:
Sage E. Hawn, Xiang Zhao, Danielle R. Sullivan, Mark Logue, Dana Fein-Schaffer, William Milberg, Regina McGlinchey, Mark W. Miller, Erika J. Wolf
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-5 (2023)
Externí odkaz:
https://doaj.org/article/79d1febdc5a6468f8345752a6af5d5d8
Autor:
Sage E. Hawn, Xiang Zhao, Danielle R. Sullivan, Mark Logue, Dana Fein-Schaffer, William Milberg, Regina McGlinchey, Mark W. Miller, Erika J. Wolf
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Psychopathology is a risk factor for accelerated biological aging and early mortality. We examined associations between broad underlying dimensions of psychopathology (reflecting internalizing and externalizing psychiatric symptoms), PTSD, a
Externí odkaz:
https://doaj.org/article/8ab126b097834057bca5eaf448d2e695
Autor:
Sage E. Foley, Christine Tuohy, Merran Dunford, Michael J. Grey, Heidi De Luca, Caitlin Cawley, Rose L. Szabady, Ana Maldonado-Contreras, Jean Marie Houghton, Doyle V. Ward, Randall J. Mrsny, Beth A. McCormick
Publikováno v:
Microbiome, Vol 9, Iss 1, Pp 1-17 (2021)
Abstract Background P-glycoprotein (P-gp) plays a critical role in protection of the intestinal epithelia by mediating efflux of drugs/xenobiotics from the intestinal mucosa into the gut lumen. Recent studies bring to light that P-gp also confers a c
Externí odkaz:
https://doaj.org/article/91d5522180234af2941f779d05d4a612
Autor:
Michael J. Grey, Heidi De Luca, Doyle V. Ward, Irini A.M. Kreulen, Katlynn Bugda Gwilt, Sage E. Foley, Jay R. Thiagarajah, Beth A. McCormick, Jerrold R. Turner, Wayne I. Lencer
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 17 (2022)
Epithelial cells lining mucosal surfaces of the gastrointestinal and respiratory tracts uniquely express ERN2/IRE1β, a paralogue of the most evolutionarily conserved endoplasmic reticulum stress sensor, ERN1/IRE1α. How ERN2 functions at the host-en
Externí odkaz:
https://doaj.org/article/b6a3451037ac41be97dfd02c6d12fa5c
Autor:
Sage E. Foley, Michael J. Dente, Xuqiu Lei, Benjamin F. Sallis, Ethan B. Loew, Mario Meza-Segura, Katherine A. Fitzgerald, Beth A. McCormick
Publikováno v:
mBio, Vol 13, Iss 4 (2022)
ABSTRACT P-glycoprotein (P-gp) is a key component of the intestinal epithelium playing a pivotal role in removal of toxins and efflux of endocannabinoids to prevent excessive inflammation and sustain homeostasis. Recent studies revealed butyrate and
Externí odkaz:
https://doaj.org/article/6f9a0174e68b46aab65cc51c0cd152b5
Autor:
Erika J. Wolf, Xiang Zhao, Sage E. Hawn, Filomene G. Morrison, Zhenwei Zhou, Dana Fein-Schaffer, Bertrand Huber, Mark W. Miller, Mark W. Logue
Publikováno v:
Neurobiology of Stress, Vol 15, Iss , Pp 100371- (2021)
Psychiatric stress has been associated with accelerated epigenetic aging (i.e., when estimates of cellular age based on DNA methylation exceed chronological age) in both blood and brain tissue. Little is known about the downstream biological effects
Externí odkaz:
https://doaj.org/article/93f590a9f0a142399f36ca6afd036009
Autor:
John P. Haran, Shakti K. Bhattarai, Sage E. Foley, Protiva Dutta, Doyle V. Ward, Vanni Bucci, Beth A. McCormick
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
ABSTRACT The microbiota-gut-brain axis is a bidirectional communication system that is poorly understood. Alzheimer’s disease (AD), the most common cause of dementia, has long been associated with bacterial infections and inflammation-causing immun
Externí odkaz:
https://doaj.org/article/2aebc885e90a4bd7bd0d7aef98886dd4