Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Safwaan Adam"'
Publikováno v:
Endocrine Connections, Vol 12, Iss 5, Pp 1-13 (2023)
Checkpoint inhibitors are now widely used in the management of many cancers. Endocrine toxicity is amongst the most common side effects. These endocrinopathies differ from most other immune-related toxicities in frequently being irreversible and rare
Externí odkaz:
https://doaj.org/article/4cd5b8b278ce47c8b11dc5765e692690
Autor:
Adrian H. Heald, Helene A. Fachim, Bilal Bashir, Bethanie Garside, Safwaan Adam, Zohaib Iqbal, Akheel A. Syed, Rachelle Donn, Carel W. Le Roux, Mahmoud Abdelaal, James White, Handrean Soran
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 16978 (2023)
Bariatric surgery improves dyslipidaemia and reduces body weight, but it remains unclear how bariatric surgery modulates gene expression in fat cells to influence the proprotein convertase subtilisin/kexin type 9 (PCSK-9) and low-density lipoprotein
Externí odkaz:
https://doaj.org/article/cd22fd9cec5b43a0b0921ff4090f3b0b
Publikováno v:
Endocrine Oncology, Vol 2, Iss 1, Pp K5-K9 (2023)
Short synacthen tests (SST) are frequently used for assessing adrenocorticotropin hormone (ACTH) deficiency. In this study, we present the case of a 53-year-old man receiving immunotherapy for metastatic melanoma, who subsequently developed immune ch
Externí odkaz:
https://doaj.org/article/1b3c4fcb0c174b04ba6a75cc915f79f5
Autor:
Shazli Azmi, Maryam Ferdousi, Yifen Liu, Safwaan Adam, Tarza Siahmansur, Georgios Ponirakis, Andrew Marshall, Ioannis N. Petropoulos, Jan Hoong Ho, Akheel A. Syed, John M. Gibson, Basil J. Ammori, Paul N. Durrington, Rayaz A. Malik, Handrean Soran
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Obesity and associated dyslipidemia may contribute to increased cardiovascular disease. Obesity has also been associated with neuropathy. We have investigated presence of peripheral nerve damage in patients with severe obesity without type 2
Externí odkaz:
https://doaj.org/article/ce6f7d4ff81f434ea4ea3b62b86da46e
Publikováno v:
BMJ Open, Vol 12, Iss 5 (2022)
Externí odkaz:
https://doaj.org/article/c867c9022a7d4a7bb1c01b9822453aa3
Autor:
Shaishav Dhage, Maryam Ferdousi, Safwaan Adam, Jan Hoong Ho, Alise Kalteniece, Shazli Azmi, Uazman Alam, Georgios Ponirakis, Ioannis Petropoulos, Andrew J. Atkinson, Andrew Marshall, Maria Jeziorska, Handrean Soran, Rayaz A. Malik
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Accurately quantifying the progression of diabetic peripheral neuropathy is key to identify individuals who will progress to foot ulceration and to power clinical intervention trials. We have undertaken detailed neuropathy phenotyping to ass
Externí odkaz:
https://doaj.org/article/6e4fe82f035548e3b5afb9e01bf828a9
Autor:
Helene A. Fachim, Kirk Siddals, Nagaraj Malipatil, Rachelle P Donn, Gabriela YC Moreno, Caroline F Dalton, Safwaan Adam, Handrean Soran, J Martin Gibson, Adrian H Heald
Publikováno v:
Adipocyte, Vol 9, Iss 1, Pp 96-107 (2020)
Aims: We investigated whether a lifestyle intervention could influence expression and DNA methylation of diabetes-related genes in patients with impaired glucose regulation (IGR), the results were compared to bariatric surgery, considering it an inte
Externí odkaz:
https://doaj.org/article/49a560e0bdf742dda62322bf8a172f6c
Autor:
Jan Hoong Ho, Kwok Leung Ong, Luisa F. Cuesta Torres, Yifen Liu, Safwaan Adam, Zohaib Iqbal, Shaishav Dhage, Basil J. Ammori, Akheel A. Syed, Kerry-Anne Rye, Fatiha Tabet, Handrean Soran
Publikováno v:
Journal of Lipid Research, Vol 62, Iss , Pp 100043- (2021)
Roux-en-Y gastric bypass (RYGB) is one of the most commonly performed weight-loss procedures, but how severe obesity and RYGB affect circulating HDL-associated microRNAs (miRNAs) remains unclear. Here, we aim to investigate how HDL-associated miRNAs
Externí odkaz:
https://doaj.org/article/a66adb2a592b4cd09d4d075da4578600
Autor:
Jan Hoong Ho, Safwaan Adam, Shazli Azmi, Maryam Ferdousi, Yifen Liu, Alise Kalteniece, Shaishav S Dhage, Brian G Keevil, Akheel A Syed, Basil J Ammori, Tomás Ahern, Rachelle Donn, Rayaz A Malik, Handrean Soran
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0221992 (2019)
ContextMultiple factors contribute to sexual dysfunction in men with obesity. Sex hormone levels are commonly abnormal in men with obesity and this abnormality is often the focus of management in clinical practice. The role of small fibre neuropathy
Externí odkaz:
https://doaj.org/article/bf9bca4eeb26426d96d99774fc180fb9
Autor:
Rahul Yadav, Salam Hama, Yifen Liu, Tarza Siahmansur, Jonathan Schofield, Akheel A. Syed, Michael France, Philip Pemberton, Safwaan Adam, Jan Hoong Ho, Reza Aghamohammadzadeh, Shaishav Dhage, Rachelle Donn, Rayaz A. Malik, John P. New, Maria Jeziorska, Paul Durrington, Basil A. Ammori, Handrean Soran
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
PurposeObesity is a major modifiable risk factor for cardiovascular disease. Bariatric surgery is considered to be the most effective treatment option for weight reduction in obese patients with and without type 2 diabetes (T2DM).ObjectiveTo evaluate
Externí odkaz:
https://doaj.org/article/072fb210cd494a048a892c11a31070c4