Biomedical aspects of pyridoxal 5 -phosphate availability

Autor: Martino Luigi di Salvo, Safo, M. K., Contestabile, R.

Publikováno v: Scopus-Elsevier

The biologically active form of vitamin B6, pyridoxal 5'-phosphate (PLP), is a cofactor in over 160 enzyme activities involved in a number of metabolic pathways, including neurotransmitter synthesis and degradation. In humans, PLP is recycled from fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1741a120b56e796d4ac598bf65431b9
https://doi.org/10.2741/e428

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Structural Basis for the Potent Antisickling Effect of a Novel Class of Five-Membered Heterocyclic Aldehydic Compounds

Autor: Safo, M. K., Abdulmalik, O., Danso-Danquah, R., Burnett, J. C., Nokuri, S., Joshi, G. S., Musayev, F. N., Asakura, T., Abraham, D. J.

Publikováno v: Journal of Medicinal Chemistry; September 2004, Vol. 47 Issue: 19 p4665-4676, 12p

Synthesis and Structure−Activity Relationships of Chiral Allosteric Modifiers of Hemoglobin

Autor: Grella, M. Phelps, Danso-Danquah, R., Safo, M. K., Joshi, G. S., Kister, J., Marden, M., Hoffman, S. J., Abraham, D. J.

Publikováno v: Journal of Medicinal Chemistry; December 14, 2000, Vol. 43 Issue: 25 p4726-4737, 12p

X-ray structure of Escherichia coli pyridoxine 5'-phosphate oxidase complexed with pyridoxal 5'-phosphate at 2.0 A resolution.

Autor: Safo MK; Institute for Structural Biology and Drug Discovery, and Department of Biochemistry, Virginia Commonwealth University, Richmond, VA 23219, USA. msafo@hsc.vcu.edu, Musayev FN, di Salvo ML, Schirch V

Publikováno v: Journal of molecular biology [J Mol Biol] 2001 Jul 20; Vol. 310 (4), pp. 817-26.