Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Safiah Mohamed Ali"'
Autor:
Jianliang Xu, P. Jaya Kausalya, Alicia Ghia Min Ong, Christine Meng Fan Goh, Safiah Mohamed Ali, Walter Hunziker
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-13 (2022)
Abstract TJP2/ZO-2-inactivating mutations in humans cause progressive cholestatic liver disease. Liver-specific deletion of Tjp2 in the mouse (Tjp2 cKO mice) leads to mild progressive cholestasis without an overt degradation of the bile-blood barrier
Externí odkaz:
https://doaj.org/article/b4277ca64cfe4e9a9e8fd858109a861d
Autor:
Dominic C Y Phua, Jianliang Xu, Safiah Mohamed Ali, Adrian Boey, Natalia V Gounko, Walter Hunziker
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99532 (2014)
The Zonula Occludens proteins ZO-1 and ZO-2 are cell-cell junction-associated adaptor proteins that are essential for the structural and regulatory functions of tight junctions in epithelial cells and their absence leads to early embryonic lethality
Externí odkaz:
https://doaj.org/article/3c0a5c2a7c5243bb807f7d7c00393cfc
Autor:
Jianliang Xu, Safiah Mohamed Ali, Wan Lu Woo, P. Jaya Kausalya, Noémi Van Hul, Philipp Kaldis, Walter Hunziker, Matias J. Caldez, Alicia Ghia Min Ong, Shiyi Xu
BACKGROUND & AIMSTight junctions (TJs) establish tissue barriers that maintain osmotic homeostasis and, in the liver, isolate bile flow from the blood circulation. ZO-2/Tjp2 is a scaffold protein that tethers TJ transmembrane proteins to the actin cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba09ad8335d27441657891aa653bad4f
Autor:
Sophia Beng Hui Lim, Safiah Mohamed Ali, Jaya P. Kausalya, Sebastian Maurer-Stroh, Vachiranee Limviphuvadh, Walter Hunziker, Jianliang Xu, Mei Yong Ng
Publikováno v:
Stem Cells. 30:1885-1900
ZO-1/Tjp1 is a cytosolic adaptor that links tight junction (TJ) transmembrane proteins to the actin cytoskeleton and has also been implicated in regulating cell proliferation and differentiation by interacting with transcriptional regulators and sign
Autor:
Safiah Mohamed Ali, Zakir Hossain, P. Jaya Kausalya, Jianliang Xu, Walter Hunziker, Dominic C.Y. Phua
ZO-1, ZO-2, and ZO-3 are closely related scaffolding proteins that link tight junction (TJ) transmembrane proteins such as claudins, junctional adhesion molecules, and occludin to the actin cytoskeleton. Even though the zonula occludens (ZO) proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4780b31d685f0be63cb9c171d35206c
https://europepmc.org/articles/PMC2258782/
https://europepmc.org/articles/PMC2258782/
Autor:
Zeng Qi, Zakir Hossain, Jianliang Xu, Safiah Mohamed Ali, Chee Peng Ng, Wanjin Hong, Hui Ling Ko, Walter Hunziker, Ke Guo, Sathivel Ponniah
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 104(5)
Wwtr1 is a widely expressed 14-3-3-binding protein that regulates the activity of several transcription factors involved in development and disease. To elucidate the physiological role of Wwtr1, we generated Wwtr1 −/− mice by homologous recombina
Autor:
Natalia V. Gounko, Walter Hunziker, Safiah Mohamed Ali, Jianliang Xu, Dominic C.Y. Phua, Adrian Boey
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99532 (2014)
PLoS ONE
PLoS ONE
The Zonula Occludens proteins ZO-1 and ZO-2 are cell-cell junction-associated adaptor proteins that are essential for the structural and regulatory functions of tight junctions in epithelial cells and their absence leads to early embryonic lethality