Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Safdar All Khan"'
Autor:
Safdar All Khan, Mark Wickstrom, Val R. Beasley, Wanda M. Haschek, David J. Schaeffer, John F. Wyman, John E. Eriksson
Publikováno v:
Toxicologic Pathology. 23:326-337
Microcystin-LR (MCLR) is a cyanobacterial hepatotoxin that inhibits intracellular serine/threonine protein phosphatases causing disruption of actin microfilaments (MFs) and intermediate filaments (IFs) in hepatocytes. This study compared the effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5686d97079671e926e27b09d664eda93
https://doi.org/10.1177/019262339502300309
https://doi.org/10.1177/019262339502300309
Autor:
Mark Wickstrom, Val R. Beasley, Shushmita Ghosh, Safdar All Khan, Rex A. Hess, Lou Ann Miller, Wanda M. Haschek
Publikováno v:
Natural Toxins. 3:119-128
The cyanobacterial toxin microcystin-LR (MCLR) is a potent inhibitor of protein phosphatases 1 and 2A, and is selectively toxic to the liver in vivo and to isolated hepatocytes in vitro. This selectivity is believed to be due to toxin uptake via bile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::939ca70bd58fc6b5ea0a9b80e7045e70
https://doi.org/10.1002/nt.2620030302
https://doi.org/10.1002/nt.2620030302
Publikováno v:
Natural toxins. 3(6)
Microcystin-LR (MCLR) is a commonly encountered blue-green algal hepatotoxin and a known inhibitor of cellular protein phosphatase types 1 and 2A. The toxin causes alterations in, and redistribution of, intermediate filaments, microtubules, and actin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31ce275214415f6a1a2c6b7fa988fe0e
https://pubmed.ncbi.nlm.nih.gov/8612002
https://pubmed.ncbi.nlm.nih.gov/8612002