Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Safa Kinaneh"'
Publikováno v:
Physiological Reports, Vol 12, Iss 13, Pp n/a-n/a (2024)
Abstract The central role of natriuretic peptides (NPs) in the complex cardio‐renal integrated physiology and organ failure has been revealed over the last four decades. Atrial natriuretic peptide (ANP), the oldest representative of the NPs family,
Externí odkaz:
https://doaj.org/article/ac9064be8d194832a32ee0d126a248f8
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Congestive heart failure (CHF) often leads to progressive cardiac hypertrophy and salt/water retention. However, its pathogenesis remains largely unclarified. Corin, a cardiac serine protease, is responsible for converting proANP and proBNP to biolog
Externí odkaz:
https://doaj.org/article/139dec32c0734de0bf606c2cf85559b5
Autor:
Zaher Armaly, Suheil Artol, Adel R. Jabbour, Amer Saffouri, Nayef Habashi, Amir Abd Elkadir, Naser Ghattas, Raymond Farah, Safa Kinaneh, William Nseir
Publikováno v:
Renal Failure, Vol 41, Iss 1, Pp 976-986 (2019)
Objective: The present study assesses whether phosphodiesterase type 5 (PDE-5) inhibitor or carnitine exert nephroprotective effects against clinical contrast-induced nephropathy (CIN). Materials and Methods: The present study consisted of three grou
Externí odkaz:
https://doaj.org/article/a55724173a584f3bbf47a866b663b002
Publikováno v:
EBioMedicine, Vol 67, Iss , Pp 103356- (2021)
Externí odkaz:
https://doaj.org/article/6b37d22e1bda4bfa9c034f4cb96aa8b6
Autor:
Safa Kinaneh, Yara Knany, Emad E Khoury, Reem Ismael-Badarneh, Shadi Hamoud, Gidon Berger, Zaid Abassi, Zaher S Azzam
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0239240 (2021)
Na+/H+ exchangers (NHEs), encoded by Solute Carrier 9A (SLC9A) genes in human, are ubiquitous integral membrane ion transporters that mediate the electroneutral exchange of H+ with Na+ or K+. NHEs, found in the kidney and intestine, play a major role
Externí odkaz:
https://doaj.org/article/a350c9d7cba74e868192a9b535ad4bcf
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Engulfed by the grave consequences of the coronavirus disease 2019 (COVID-19) pandemic, a better understanding of the unique pattern of viral invasion and virulence is of utmost importance. Angiotensin (Ang)-converting enzyme (ACE) 2 is a key compone
Externí odkaz:
https://doaj.org/article/5df172886bd344bb8095797d37f116b8
Publikováno v:
Data in Brief, Vol 20, Iss , Pp 1305-1308 (2018)
This data article contains analysis of data observed in E0 mice placed on high fat diet, and treated by intraperitoneal injections of either normal saline (control) or the heparanase inhibitor PG545, in two different doses. Mice body weights and food
Externí odkaz:
https://doaj.org/article/14a9b32277ba4677aa5a20a3e4adbdf4
Involvement of Cytokines in the Pathogenesis of Salt and Water Imbalance in Congestive Heart Failure
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Congestive heart failure (CHF) has become a major medical problem in the western world with high morbidity and mortality rates. CHF adversely affects several systems, mainly the kidneys and the lungs. While the involvement of the renin–angiotensin
Externí odkaz:
https://doaj.org/article/a119f33fe66f40fbbc148f47659bbb84
Autor:
Safa Kinaneh, Emad E. Khoury, Samuel N. Heyman, Zaher S. Azzam, Yara Knaney, Ahmad Fokra, Zaid Abassi
Publikováno v:
Journal of Cellular and Molecular Medicine
Congestive heart failure (CHF) is often associated with kidney and pulmonary dysfunction. Activation of the renin‐angiotensin‐aldosterone system (RAAS) contributes to avid sodium retention, cardiac hypertrophy and oedema formation, including lung
Publikováno v:
Journal of Cellular and Molecular Medicine
Endothelial dysfunction (ED) is a key feature of diabetes and is a major cause of diabetic vasculopathy. Diabetic patients who also exhibit hyperlipidaemia suffer from accelerated vascular complications. While the deleterious effects of high glucose